Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4 Mimọ>98.0% (HPLC) Ile-iṣẹ Alagbedemeji Lenvatinib Mesylate
Ipese Kemikali Ruifu Lenvatinib Mesylate Intermediates Pẹlu Iwa mimọ to gaju
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1- (2-Chloro-4-Hydroxyphenyl) -3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5- (Methoxymethylene) -2,2-Dimethyl-1,3-Dioxane-4,6-Dion CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4
Orukọ Kemikali | Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate |
Awọn itumọ ọrọ sisọ | Lenvatinib Aimọ 47;4-Chloro-7-Methoxyquinoline-6-Carboxylic Acid Methyl Ester;4-Chloro-7-Methoxy-6-Quinolinecarboxylic Acid Methyl Ester;Lenvaint-D |
Nọmba CAS | 205448-66-4 |
NỌMBA CAT | RF-PI1970 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
Ilana molikula | C12H10ClNO3 |
Òṣuwọn Molikula | 251.67 |
Ojuami farabale | 377,4 ± 37,0 ℃ |
iwuwo | 1.320 ± 0,06 g / cm3 |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Pa-White to Yellow ri to Powder |
1 H NMR julọ.Oniranran | Ni ibamu Pẹlu Be |
Mimọ / Analysis Ọna | > 98.0% (HPLC) |
Pipadanu lori Gbigbe | <1.00% |
Lapapọ Awọn Aimọ | <2.00% |
Igbeyewo Standard | Standard Enterprise |
Lilo | Agbedemeji/Aimọ ti Lenvatinib Mesylate (CAS: 857890-39-2) |
Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate (CAS: 205448-66-4) jẹ agbedemeji ti Lenvatinib Mesylate (CAS: 857890-39-2).Lenvatinib jẹ oogun akàn tairodu ti o ni idagbasoke nipasẹ Eisai Corporation of Japan (koodu: E7080), ti o jẹ ti oludena ti oral multi-receptor tyrosine kinase (RTK) ati pe o le dẹkun iṣẹ kinase ti iṣan endothelial idagbasoke ifosiwewe Awọn olugba R1 (FLT1), VEG-FR2 (KDR), R3 (FLT4).Lenvatinib tun le dẹkun ilowosi ti awọn RTK miiran ni angiogenesis pathological, idagbasoke tumo, ati ilọsiwaju akàn ayafi fun awọn iṣẹ cellular deede wọn pẹlu fibroblast growth factor (FGF) awọn olugba FGFR1, 2, 3, ati 4;Olugba ifosiwewe idagbasoke ti platelet (PDGFR [alpha]), KIT, ati RET.[Awọn itọkasi]: Lenvatinib jẹ o dara fun itọju awọn alaisan ti akàn tairodu ti iṣipopada agbegbe tabi iru metastasis, iru ilọsiwaju ati ipanilara iodine-refractory differentiated type.