Methyl (S) -2- (Boc-amino) -3- [(S) -2-oxo-3-pyrrolidinyl] propanoate CAS 328086-60-8 PF-07321332 Boceprevir Intermediate

Apejuwe kukuru:

Orukọ Kemikali: Methyl (S)-2- (Boc-amino) -3-[(S)-2-oxo-3-pyrrolidinyl] propanoate

CAS: 328086-60-8

Irisi: Funfun si Paa-White Powder

Agbedemeji ti PF-07321332 Paxlovid (CAS 2628280-40-8) ati Boceprevir (CAS 394730-60-0)

Didara to gaju, iṣelọpọ Iṣowo

Inquiry: alvin@ruifuchem.com

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Jẹmọ Products

ọja Tags

Apejuwe:

Ipese Iṣowo PF-07321332 Awọn agbedemeji ti o jọmọ Paxlovid pẹlu Didara Giga
L-tert-Leucine (H-Tle-OH) CAS 20859-02-3
Caronic Anhydride CAS 67911-21-1
(1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-Carboxylic Acid Methyl Ester Hydrochloride 565456-77-1
Methyl (S) -2- (Boc-amino) -3- [(S) -2-oxo-3-pyrrolidinyl] propanoate CAS 328086-60-8
6,6-Dimethyl-3-azabicyclo[3.1.0] hexane CAS 943516-54-9

Kemikali Properties:

Orukọ Kemikali	Methyl (S)-2- (Boc-amino) -3- [(S) -2-oxo-3-pyrrolidinyl] propanoate
Awọn itumọ ọrọ sisọ	Methyl (S) -2- ((tert-butoxycarbonyl) amino) -3- ((S) -2-oxopyrrolidin-3-yl) propanoate;(αS,3S) -α- [(tert-Butyloxycarbonyl) aMino] -2-oxo-3-pyrrolidinepropanoic acid Methyl Ester;(S) -Methyl 2- ((tert-butoxycarbonyl) amino) -3- ((S) -2-oxopyrrolidin-3-yl) propanoate.
Nọmba CAS	328086-60-8
NỌMBA CAT	RF-PI317
Iṣura Ipo	Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn ọgọọgọrun Kilogram
Fọọmu Molecular	C13H22N2O5
Òṣuwọn Molikula	286.33
Brand	Ruifu Kemikali

Awọn pato:

Nkan	Awọn pato
Ifarahan	Funfun to Pa-White Powder
Idanimọ A	IR: Iru si nkan Itọkasi
Idanimọ B	Akoko Idaduro: Iru si nkan Itọkasi
Pipadanu lori Gbigbe	≤1.0%
Aloku lori Iginisonu	≤0.20%
Aimọ Kanṣoṣo	≤0.50%
Lapapọ Awọn Aimọ	≤2.0%
Awọn Irin Eru (Pb)	≤20ppm
Mimo	≥98.0%
Igbeyewo Standard	Standard Enterprise
Lilo	Agbedemeji ti PF-07321332 Paxlovid (CAS 2628280-40-8) ati Boceprevir (CAS 394730-60-0)

Package & Ibi ipamọ:

Package: Igo, apo apamọwọ Aluminiomu, ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.

Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.

Awọn anfani:

FAQ:

Ohun elo:

Methyl (S) -2- (Boc-amino) -3- [(S) -2-oxo-3-pyrrolidinyl] propanoate (CAS 328086-60-8) jẹ agbedemeji ti PF-07321332 Paxlovid (CAS 2628280-40). -8) ati Boceprevir (CAS 394730-60-0).PF-07321332, paati bọtini ti Paxlovid (PF-07321332 ati Ritonavir) eyiti o jẹ iwadii COVID-19 ti o jẹ oludije antiviral oral, jẹ inhibitor 3C-like protease (3CLPRO) ti ẹnu pẹlu awọn ipa antiviral ti o lagbara lodi si ọlọjẹ SARS-CoV-2 ati COVID-19.Ni Oṣu kọkanla ọjọ 6th, ọdun 2021, Pfizer kede pe Paxlovid dinku ni pataki ile-iwosan ati iku, da lori itupalẹ igba diẹ ti Alakoso 2/3 EPIC-HR (Iyẹwo ti Inhibition Protease fun COVID-19 ni Awọn Alaisan Ewu Giga) laileto, iwadii afọju meji ti awọn alaisan agbalagba ti kii ṣe ile-iwosan pẹlu COVID-19, ti o wa ninu eewu giga ti lilọsiwaju si aisan nla.Boceprevir (EBP-520) jẹ inhibitor protease HCV (Ki=14 nM) fun itọju ikolu arun jedojedo C.Boceprevir pẹlu pegylated interferon ati ribavirin (PegIFN/RBV) jẹ ki ilọsiwaju ni awọn oṣuwọn esi ti ọlọjẹ ti o tẹsiwaju ti awọn alaisan pẹlu genotype 1 HCV.Boceprevir ṣe ajọṣepọ pẹlu itọju ajẹsara ajẹsara (IT) nipa didi cytochrome P450 3A enzymu.