Molnupiravir N-1 CAS 2346620-55-9 COVID-19 Didara Giga
Ipese Iṣowo Molnupiravir ati Awọn agbedemeji ibatan pẹlu Didara Giga
Uridine CAS 58-96-8
Cytidine CAS 65-46-3
Molnupiravir N-1 CAS 2346620-55-9
Molnupiravir (EIDD-2801) CAS 2349386-89-4
| Orukọ Kemikali | Molnupiravir N-1 |
| Awọn itumọ ọrọ sisọ | ((3aR,4R,6R,6aR) -6-((E) -4- (hydroxyimino) -2-oxo-3,4-dihydropyrimidin-1 (2H) -yl) -2,2-dimethyltetrahydrofuro[3, 4-d [1,3] dioxol-4-yl) methyl isobutyrate;Molnupiravir Intermediate;Molnupiravir Dimethyl Dioxol Aimọ;Molnupiravir Aimọ 11 |
| Nọmba CAS | 2346620-55-9 |
| NỌMBA CAT | RF-PI310 |
| Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn ọgọọgọrun Kilogram |
| Fọọmu Molecular | C16H23N3O7 |
| Òṣuwọn Molikula | 369.37 |
| Solubility | Tiotuka ni DMSO |
| iwuwo | 1,51 ± 0,1 g / cm3 |
| Sowo otutu | Ibaramu |
| Brand | Ruifu Kemikali |
| Nkan | Awọn pato |
| Ifarahan | Funfun to Pa-White Powder |
| Pipadanu lori Gbigbe | ≤1.0% |
| Aloku lori Iginisonu | ≤0.20% |
| Aimọ Kanṣoṣo | ≤0.50% |
| Lapapọ Awọn Aimọ | ≤2.0% |
| Awọn irin Heavy | ≤20ppm |
| Mimo | ≥98.0% |
| Igbeyewo Standard | Standard Enterprise |
| Lilo | Agbedemeji ti Molnupiravir (CAS 2349386-89-4) COVID-19 |
Package: Igo, apo apamọwọ Aluminiomu, ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.
Molnupiravir N-1 (CAS 2346620-55-9), jẹ agbedemeji ti Molnupiravir (CAS 2349386-89-4) ni itọju COVID-19.Molnupiravir (EIDD-2801) jẹ fọọmu bioavailable ẹnu ti afọwọṣe ribonucleoside ti o lagbara pupọ ti o ṣe idiwọ ẹda ti ọpọlọpọ awọn ọlọjẹ RNA pẹlu SARS-CoV-2, aṣoju okunfa ti COVID-19.EIDD-2801 (7 mg/kg; po; lẹmeji ojoojumo fun awọn ọjọ 3.5) dinku iwuwo ọlọjẹ ti o ta silẹ ati iye akoko iba.Molnupiravir (EIDD-2801) jẹ hydrolyzed daradara ni vivo lẹhin gbigba, ti o yorisi wiwa ti NHC ọfẹ nikan ni pilasima.EIDD-2801 logan dinku awọn titers àkóràn MERS-CoV, gbogun ti RNA, ati pathogenesis labẹ mejeeji prophylactic ati awọn ipo itọju ailera ni kutukutu.Molnupiravir (EIDD-2801, MK-4482) jẹ arosọ bioavailable ẹnu ti ribonucleoside afọwọṣe β-d-N4-hydroxycytidine (NHC; EIDD-1931) pẹlu iṣẹ ṣiṣe antiviral ti o gbooro si SARS-CoV-2, MERS-CoV, SARS-CoV, ati aṣoju okunfa ti COVID-19.
