N-Acetyl-L-Tyrosine CAS 537-55-3 (Ac-Tyr-OH; NALT) Assay 99.0 ~ 101.0 Factory
Shanghai Ruifu Chemical Co., Ltd jẹ olupilẹṣẹ asiwaju ati olupese ti N-Acetyl-L-Tyrosine (Ac-Tyr-OH; NALT) (CAS: 537-55-3) pẹlu didara to gaju.Kemikali Ruifu n pese lẹsẹsẹ awọn amino acids ati awọn itọsẹ.Ọja didara to gaju, idiyele ti o tọ, o tayọ ati iyara lẹhin iṣẹ-tita jẹ awọn adehun ti Kemikali Ruifu si awọn alabara.A le pese COA, ifijiṣẹ agbaye, kekere ati titobi pupọ ti o wa.Ti o ba nifẹ si N-Acetyl-L-Tyrosine,Please contact: alvin@ruifuchem.com
Orukọ Kemikali | N-Acetyl-L-Tyrosine |
Awọn itumọ ọrọ sisọ | AC-Tyr-OH;AC-L-Tyr-OH;N-Ac-L-Tyr;NALT;Ac-Tirosini;Acetyltyrosine;N-Acetyltyrosine;Acetyl-Laevo-Tyrosine;LN-Acetyltyrosine;(2S) -2- (Acetylamino) -3- (4-Hydroxyphenyl) Propanoate;(S) -2-Acetamido-3- (4-Hydroxyphenyl) Acid propanoic;N-Acetyl-(S)-2-Amino-3- (4-Hydroxyphenyl) Acid propionic;(2S) -2- (Acetylamino)-3- (4-Hydroxyphenyl) Acid propanoic |
Iṣura Ipo | Ninu Iṣura, Agbara iṣelọpọ 30 Toonu fun Ọdun |
Nọmba CAS | 537-55-3 |
Fọọmu Molecular | C11H13NO4 |
Òṣuwọn Molikula | 223,23 g / mol |
Ojuami Iyo | 150.0 si 154.0 ℃ |
iwuwo | 1.304 |
Omi Solubility | Tiotuka ninu Omi, Fere akoyawo |
Ibi ipamọ otutu. | Ididi ni Gbẹ, Itaja ni Yara otutu |
COA & MSDS | Wa |
Iyasọtọ | Amino Acids & Awọn itọsẹ |
Brand | Ruifu Kemikali |
Awọn koodu ewu | Xi - Irritant | F | 10 |
Awọn Gbólóhùn Ewu | 41-36/37/38 | TSCA | Bẹẹni |
Awọn Gbólóhùn Aabo | 26-39-36 | HS koodu | 2922491990 |
WGK Germany | 3 |
Awọn nkan | Ayewo Standards | Esi |
Ifarahan | Awọn kirisita funfun tabi Crystalline Powder | Ni ibamu |
Idanimọ | Infurarẹẹdi Absorption julọ.Oniranran | Ni ibamu |
Yiyi pato [α] 20/D | +46.5° si +49.0°(C=2 ninu H2O) | + 47,2 ° |
Ipo Solusan (Gbigbepo) | ≥96.0% | 98.3% |
Kloride (Cl) | ≤0.020% | <0.020% |
Sulfate (SO4) | ≤0.020% | <0.020% |
Ammonium (NH4) | ≤0.020% | <0.020% |
Irin (Fe) | ≤30ppm | <30ppm |
Awọn Irin Eru (Pb) | ≤10ppm | <10ppm |
Arsenic (As2O3) | ≤2.0pm | <2.0ppm |
Tyrosini | ≤1.00% | Ni ibamu |
Pipadanu lori Gbigbe | ≤0.50% | 0.25% |
Ajẹkù lori Iginisonu (Sulfated) | ≤0.10% | 0.07% |
Ayẹwo | 99.0 si 101.0% | 99.5% |
Iye pH | 2.0 to 3.0 | 2.3 |
Ipari | Pade Standard of AJI97, USP35 | |
Awọn Lilo akọkọ | Awọn afikun ounjẹ ounjẹ;Awọn afikun Ounjẹ;elegbogi Intermediates |
N-Acetyl-L-Tyrosine (Ac-Tyr-OH; NALT) (CAS: 537-55-3) Ọna Idanwo AJI97
N-Acetyl-L-Tyrosine, nigba ti o gbẹ, ko kere ju 99.0 ogorun ko si ju 101.0 ogorun ti N-Acetyl-L-Tyrosine (C11H13NO4).
Apejuwe: Awọn kirisita funfun tabi lulú kirisita, itọwo acid lagbara
Larọwọto tiotuka ninu omi.
Solubility (H2O, g/100g): 17.5 (20℃), 72.4 (40℃), 158 (60℃)
Idanimọ: Ṣe afiwe irisi gbigba infurarẹẹdi ti ayẹwo pẹlu ti boṣewa nipasẹ ọna disiki bromide potasiomu.
Yiyi pato [α] 20/D: Ayẹwo ti o gbẹ, C = 4, H2O
Ipo Solusan (Igbejade): 0.5g ni 10ml ti H2O, spectrophotometer, 430nm, 10mm cell sisanra.
Chloride (Cl): 0.7g, A-1, atunṣe: 0.40ml ti 0.01mol/L HCl
Ammonium (NH4): B-1
Sulfate (SO4): 1.2g, (1), atunṣe: 0.50ml ti 0.005mol/L H2SO4
Iron (Fe): 0.5g, Ref: 1.5ml of Iron Std.(0.01mg/ml)
Awọn irin Eru (Pb): 2.0g, (3), atunṣe: 2.0ml ti Pb Std.(0.01mg/ml)
Arsenic (As2O3): 1.0g, (1), atunṣe: 2.0ml ti As2O3 Std.
Pipadanu lori Gbigbe: ni 105 ℃ fun awọn wakati 3
Ajẹkù lori Ignition (Sulfated): Idanwo AJI 13
Ayẹwo: Ayẹwo ti o gbẹ, 300mg, (1), 40ml H2O, (2), 0.1mol/L NaOH, 1ml=22.323mg C11H13NO4
Tyrosine: chromatography olomi.Ipo ṣiṣiṣẹ: Oluwadi: photometer gbigba UV (214nm);Ọwọn: ODS, 4.6mm x 150mm;Iwọn otutu iwe: Iwọn otutu yara.Oṣuwọn sisan: 1ml/min;Ipele alagbeka: 0.04mol/L ojutu ti monopotassium fosifeti (pH 4.35): kẹmika (193: 3)
pH: 1.25g ninu 50ml ti H2O
Iwọn ibi ipamọ ti a ṣe iṣeduro ati ipo: Awọn apoti wiwu ti a tọju ni iwọn otutu yara ti iṣakoso (ọdun 2).
N-Acetyl-L-Tyrosine (Ac-Tyr-OH; NALT) (CAS: 537-55-3) Ọna Idanwo USP35
ITUMO
N-Acetyltyrosine ni NLT 98.5% ati NMT 101.0% ti C11H13NO4, bi N-Acetyl-L-Tyrosine, ṣe iṣiro lori ipilẹ gbigbẹ.
Ìdámọ̀
A. INFRED ABSORPTION <197K>
B. Iyipo opitika, Yiyi pato <781S>
Ojutu ayẹwo: 10 mg/ml
Awọn ilana gbigba: NLT +46.0° ati NMT +49.0°, pinnu ni 20°
C. Iye RF ti aaye akọkọ ti ojutu Ayẹwo ninu idanwo fun Awọn aiṣedeede Organic ni ibamu si ti ojutu Standard 1.
ASAY
Ilana
Ojutu Apeere: Tu nipa 180 miligiramu ti N-Acetyltyrosine, ni iwuwo, ni 50 milimita ti omi ti ko ni erogba oloro.
Titrimetric eto
(Wo Titrimetry <541>)
Ipo: Taara titration
Titrant: 0.1 N soda hydroxide VS
Wiwa ipari: Potentiometric
Idogba: ML kọọkan ti 0.1 N sodium hydroxide VS jẹ deede si 22.32 mg ti C11H13NO4.
ALÁÌṢẸ́
Awọn Egbin Aiṣedeede
IBINU AGBEGBE <281>: NMT 0.1%
KHLORIDE ATI SULFATE, Kloride <221> NMT 200 ppm.Apa 0.7-g kan fihan ko si kiloraidi diẹ sii ju ibaamu 0.40 mL ti 0.01 N hydrochloric acid.
KHLORIDE ATI SULFATE, Sulfate <221> NMT 200 ppm.Apa kan 1.2-g fihan ko si imi-ọjọ diẹ sii ju ibaamu 0.25 milimita ti 0.020 N sulfuric acid.
IRIN <241>: NMT 20ppm
Awọn irin eru, Ọna I <231>: NMT 10ppm
Organic impurities
Ilana
Adsorbent: 0.25-mm Layer ti chromatographic silica gel mix
Ojutu ọja iṣura boṣewa 1: 8 mg/mL ti USP N-Acetyl-L-tyrosine RS ninu adalu omi, glacial acetic acid, ati oti (3:3:94)
Ojutu boṣewa 1: Dilute Standard ojutu ojutu 1 pẹlu oti lati gba ojutu kan nini ifọkansi ti a mọ ti nipa 0.4 mg/mL
Ojutu boṣewa 2: 0.8 mg/mL ti USP L-Tyrosine RS tituka ni adalu glacial acetic acid ati omi (1: 1), ati ti fomi po pẹlu oti
Ojutu Ayẹwo: Gbigbe 0.8 g ti N-Acetyltyrosine si 10-mL volumetric flask, tu ni 6 milimita ti adalu glacial acetic acid ati omi (1: 1), ati dilute pẹlu oti si iwọn didun.
Iwọn ohun elo: 5µL
Idagbasoke eto epo: Adalu amonia ati 2-propanol (3: 7)
Sokiri reagent: Tu 0.2 g ti ninhydrin ni 100 milimita ti adalu butanol ati 2 N acetic acid (95: 5).
Ibamu eto
Awọn ibeere ibamu: chromatogram ti ojutu ibaamu eto ṣe afihan awọn aaye meji ti o yapa kedere.
Itupalẹ: Tẹsiwaju bi a ti ṣe itọsọna fun Chromatography <621>Kromatography tin-Layer.Lẹhin ti afẹfẹ-gbigbe awo, tun ilana idagbasoke.Lẹhin gbigbe afẹfẹ ni akoko keji, fun sokiri pẹlu reagent sokiri, ati ooru laarin 100 ° ati 105° fun bii iṣẹju 15.
Awọn ibeere gbigba: Eyikeyi aaye keji ti ojutu Ayẹwo ko tobi tabi diẹ sii ju aaye akọkọ ti ojutu Standard1, ayafi fun aaye ti o baamu si tyrosine, eyiti ko tobi tabi kikan ju aaye akọkọ lati ojutu Standard 2.
Awọn aimọ ẹnikọọkan: NMT 0.5%
Idiwọn ti tyrosine: NMT 1.0%
Awọn idanwo pataki
LOSSON gbigbẹ <731>: Gbẹ ayẹwo ni 105 ℃ fun wakati 3: o padanu NMT 0.1% ti iwuwo rẹ.
Awọn ibeere afikun
Iṣakojọpọ ati Ipamọ: Fipamọ sinu awọn apoti ti o ni pipade daradara, ati tọju ni iwọn otutu yara ti a ṣakoso.
USP ÌRÁNTÍ awọn ajohunše <11>
USP N-Acetyl-L-tyrosine RS
USP L-Tyrosine RS
Bawo ni lati Ra?Jọwọ kan siDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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DidaraIdaniloju?Eto iṣakoso didara to muna.Awọn ohun elo ọjọgbọn fun itupalẹ pẹlu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, bbl
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MOQ?Ko si MOQ.Ibere kekere jẹ itẹwọgba.
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Aṣa Synthesis?Le pese awọn iṣẹ iṣelọpọ aṣa lati baamu awọn iwulo iwadii rẹ dara julọ.
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Iṣẹ & Ohun elo ti N-Acetyl-L-Tyrosine (Ac-Tyr-OH; NALT) (CAS: 537-55-3) lulú
1. N-Acetyl-L-Tyrosine jẹ itọsẹ acetyl ti amino acid, L-tyrosine.O jẹ tiotuka larọwọto ninu omi ni akawe si L-tyrosine ati pe a lo nigbagbogbo bi afikun ijẹẹmu parenteral.N-Acetyl-L-Tyrosine , fọọmu ti o ni iduroṣinṣin ati diẹ sii ti tyrosine, ni a ti dapọ ni diẹ ninu awọn iṣelọpọ amino acid parenteral ti owo lọwọlọwọ gẹgẹbi TrophAmine ati Aminosyn-II.
2. N-Acetyl-L-Tyrosine ni ipa ninu iṣelọpọ catecholamine.O le ṣee lo bi paati media media aṣa sẹẹli ni bioomanufacture ti iṣowo ti awọn ọlọjẹ isọdọkan ati awọn ọlọjẹ monoclonal.
3. N-Acetyl-L-Tyrosine jẹ amino acids pataki, eyiti o jẹ iru ounjẹ pataki fun eniyan ati ti iṣelọpọ ti ẹranko, idagbasoke ati idagbasoke ṣe ipa pataki, le ṣee lo ni lilo pupọ ni ounjẹ, oogun ati bẹbẹ lọ.
4. N-Acetyl-L-Tyrosine ṣe ipa pataki ninu iṣelọpọ ti dopamine ati awọn homonu miiran ninu ara rẹ.O le ṣe alekun awọn ipele ti awọn neurotransmitters dopamine, norẹpinẹpirini ati efinifirini.O ṣe iranlọwọ lati ṣe atilẹyin awọn ipele ti o ga julọ ti idojukọ ati iṣẹ oye.O le ṣe alekun iranti iṣẹ ati awọn ikunsinu ti alafia.
5. N-Acetyl-L-Tyrosine ti wa ni iyipada lati deede Tyrosine nitori pe o ni afikun ti acetic acid.Eyi ṣe iranlọwọ gaan lati mu alekun bioavailability ti agbo naa pọ si ki o dara julọ ti o gba taara sinu ẹjẹ.
6. N-Acetyl-L-Tyrosine jẹ fọọmu bioavailable ti o ga julọ ti L-Tyrosine fun itọju iṣaju adayeba ti awọn iṣesi kekere N-Acetyl-L-Tyrosine le ṣee lo ni awọn iwọn kekere ju L-Tyrosine.L-Tyrosine deede ko ni iduroṣinṣin ati inoluble ninu omi, eyiti o le ja si idinku bioavailability.
7. N-Acetyl-L-Tyrosine n mu iyọdafẹ ati iduroṣinṣin mu ki o ni kiakia ti o ni kiakia ati fọọmu bioavailable ti amino acid L-Tyrosine ti o kere si itọsi ito.