N-Fluorobenzenesulfonimide (NFSI) CAS 133745-75-2 Mimọ> 98.0% (HPLC) Fluorinating Reagent

N-Fluorobenzenesulfonimide (NFSI) (CAS: 133745-75-2), Wapọ fluorinating reagent lo ninu fluorination ti aryls, enolates, carbanions, organolithiums, ati be be lo.
N-Fluorobenzenesulfonimide jẹ aṣoju fluorinating elekitirofiki ti a lo nigbagbogbo ni iṣelọpọ Organic lati ṣafihan fluorine sinu awọn ohun elo Organic didoju.A tun lo lati fluorinate awọn sobusitireti nucleophilic gẹgẹbi awọn ẹya organometallic ifaseyin ati awọn anions malonate.NFSi le ṣepọ nipasẹ iṣesi ti benzenesulfonimide pẹlu fluorine.
N-Fluorobenzenesulfonimide jẹ tuntun, iduroṣinṣin ati irẹlẹ fluorination reagent, eyiti o le ṣafihan awọn ọta fluo rine sinu ipo carbonyl ortho ti awọn ohun alumọni Organic, ati pe o le ṣe ifasẹpọ monofluorination lori awọn agbo ogun aromatic ọlọrọ elekitironi, enol sila ne, ene Chemicalbook oti litiumu iyọ, bbl Awọn aaye iwadii lọwọlọwọ pẹlu iṣesi cyclization Nazarov ti o jẹ catalyzed nipasẹ irin tabi koluboti lati ṣe oruka marun-membered, ati catalysis asymmetric ti enantioselective α-fluorination.
N-Fluorobenzenesulfonimide fluorinates aromatics, enolates, azaenolates ati awọn carbanions ni ikore giga.O jẹ lilo fun fluorination diastereoselective ti Li enolates ti chiral carboximides, fun fluorination ti a darí ti awọn aromatics ortho-lithated ati fun atunyẹwo ti awọn aṣoju fluorinating NF electrophilic.Awọn fluorinations asymteric ni a ṣe ni iwaju eto ayase Pd-BINAP ni iwọn otutu yara ninu omi ionic kan.O jẹ reagent ti a gbaṣẹ ni palladium-catalyzed enantioselective fluorination ti t-butoxycarbonyl lactones ati awọn lactams.O tun lo ni difluorination electrophilic ti dihalopyridines pẹlu butyl lithium ati ni iyipada taara ti awọn oti si dibenzenesulfonamides pẹlu triphenylphosphine.