N-Hydroxysuccinimide (HOSu) CAS 6066-82-6 Isọpọ Reagent Mimọ> 99.0% (HPLC)

N-Hydroxysuccinimide (HOSu) (CAS: 6066-82-6), reagent fun igbaradi ti awọn esters ti nṣiṣe lọwọ ti amino acids.Peptide ri to ipele kolaginni asopo ohun.
N-Hydroxysuccinimide nigbagbogbo ni a lo lati ṣe iranlọwọ idapọ peptide mediated carbodiimide nipa ṣiṣe agbedemeji ester ti nṣiṣe lọwọ nipasẹ isọdọkan ti ẹgbẹ carboxyl dada ati NHS.NHS-reactive ester agbedemeji jẹ ifaragba si ikọlu nucleophilic nipasẹ awọn amines akọkọ ati awọn abajade ni dida awọn ifunmọ amide iduroṣinṣin laarin aaye biomaterial ati N-terminus ti peptide.
N-Hydroxysuccinimide jẹ succinimide hydroxylated ti o jẹ lilo pupọ ni ṣiṣiṣẹ ti awọn acids carboxylic si NHS-esters lati ṣe igbelaruge idapọ pẹlu awọn nucleophiles.Ọna yii jẹ iṣẹ ti o wọpọ julọ ni ṣiṣiṣẹ awọn fọọmu acid ọfẹ ti fluorophores fun igbega isọdọkan ti awọn fluorophores wọnyi si awọn iṣẹku amine ti awọn ọlọjẹ.Lilo imuṣiṣẹ ester NHS tun ti ṣe apejuwe ninu iṣelọpọ ti N-acyl amino acids.
Ti a lo fun iṣelọpọ ti idaabobo amino acid, kanamycin ologbele-synthetic ati awọn agbedemeji elegbogi.N-hydroxybutyldiimide ati awọn itọsẹ rẹ jẹ awọn ohun elo aise pataki fun iṣelọpọ ti awọn peptides, awọn egboogi, amino acids ati awọn ọlọjẹ.N-hydroxybutyldiimide ni a lo ni igbaradi ti nṣiṣe lọwọ. esters, ati awọn idinamọ ti awọn optically lọwọ ipa ti peptide pọ ni o ni kan jakejado ibiti o ti USES ni oogun, ati ki o jẹ tun kan ipilẹ kemikali aise ohun elo.
N-Hydroxysuccinimide ni a lo fun imudara amidations ni ọna carbodiimide.O tun lo lati mu ẹgbẹ carboxyl ṣiṣẹ ati ṣe atunṣe pẹlu amine lati ṣe amide.O ṣe alabapin ninu igbaradi ti N-hydroxymaleimide-styrene copolymer.