Octreotide Acetate CAS 83150-76-9 Peptide Purity (HPLC) ≥98.0% API Didara Giga

Apejuwe kukuru:

Orukọ Kemikali: Octreotide Acetate

CAS: 83150-76-9

Irisi: White Powder

Peptide Mimọ (Nipasẹ HPLC): ≥98.0%

Ayẹwo: 95% ~ 105%

Acromegaly ati Gastroenteropancreatic Tumors

Olubasọrọ: Dokita Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Apejuwe:

Shanghai Ruifu Chemical Co., Ltd jẹ olupilẹṣẹ asiwaju ti Octreotide Acetate (CAS: 83150-76-9) pẹlu didara to gaju.Ruifu Kemikali n pese lẹsẹsẹ ti awọn peptides GMP.Ruifu le pese ifijiṣẹ agbaye, idiyele ifigagbaga, kekere ati awọn iwọn olopobobo ti o wa.Ra Octreotide Acetate,Please contact: alvin@ruifuchem.com

Kemikali Properties:

Orukọ Kemikali Octreotide acetate
Awọn itumọ ọrọ sisọ SMS 201-995;Samilstin;Octreotide-LAR;
Awọn ilana D-Phe-c[Cys-Phe-D-Trp-Lys-Thr-Cys] -Thr-ol
ERIN [FCFWKTCT(Afara Disulfide: Cys2-Cys7)]
Nọmba CAS 83150-76-9
Iṣura Ipo Ninu Iṣura, Iwọn iṣelọpọ Ti o to Kilograms
Fọọmu Molecular C49H66N10O10S2
Òṣuwọn Molikula 1019.24
Ojuami Iyo > 140 ℃ (oṣu kejila)
iwuwo 1,39 ± 0,10 g / cm3
Solubility Soluble ni Acetic Acid, DMSO, ati Methanol
Iduroṣinṣin Hygroscopic
Ibi ipamọ otutu. Itura & Ibi Gbẹ (2 ~ 8℃).Firiji
Iwe aṣẹ COA, MS, HPLC, NMR, MSDS, ati bẹbẹ lọ.
Ẹka Awọn Peptides GMP
WGK Germany 3
Sowo ibeere Ice baagi, Desiccant baagi
Brand Ruifu Kemikali

Awọn pato:

Awọn nkan Ayewo Standards Esi
Ifarahan Funfun Powder Funfun Powder
Solubility Tiotuka ninu Omi tabi 1% acetic Acid ni Ifojusi kan ti ≥1mg/ml lati Fun Solusan Alailowaya Ni ibamu
Iṣayẹwo Amino Acid (Nipasẹ HPLC) Thr: 0.7 ~ 1.1 0.9
Cys: 1.0 ~ 2.2 1.9
Lys: 0.9 ~ 1.3 1.1
Phe: 1.8 ~ 2.2 1.9
Thr-OL: 0.6 ~ 1.3 0.9
Trp: 0.4 ~ 1.1 0.8
Peptide Mimọ (Nipasẹ HPLC) ≥98.0% (nipasẹ Isopọpọ Agbegbe) 99.81%
Awọn nkan ti o jọmọ (Nipasẹ HPLC) Lapapọ Awọn Aimọ (%) ≤2.0% 0.19%
Aimọ Ẹyọkan ti o tobi julọ (%) ≤1.0% 0.12%
Akoonu Acetate (HPLC) 5.0 ~ 12.8% 9.6%
Akoonu Omi (Karl Fischer) ≤7.0% 2.7%
Akoonu TFA (Karl Fischer) ≤0.25% 0.13%
Specific Optical Yiyi -45.0°~-55.0° (C=0.5, 95% HAc) -51.5°
Ayẹwo 95.0 ~ 105.0% (Anhydrous, Acetic Acid Ọfẹ) 99.0%
Oti ti Ọja Sintetiki  
Ifarabalẹ Fun Iwadi Nikan, Kii ṣe Fun Lilo Eniyan  
Ipari Ọja naa ti ni idanwo & ni ibamu pẹlu awọn pato
Lilo Awọn Peptides GMP;Ohun elo elegbogi ti nṣiṣe lọwọ (API)

Package & Ibi ipamọ:

Apo:Vial ṣiṣu (igbẹhin fun iṣakojọpọ peptide) tabi vial gilasi, opoiye ni ibamu si ibeere alaye alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti edidi ni itura ati ki o gbẹ (2 ~ 8℃) ile itaja kuro lati awọn nkan ti ko ni ibamu.Dabobo lati ina ati ọrinrin.
Gbigbe:Firanṣẹ si agbaye nipasẹ FedEx / DHL Express.Pese ifijiṣẹ yarayara ati igbẹkẹle.

Awọn anfani:

1

FAQ:

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Ohun elo:

Octreotide Acetate (Sandostatin) jẹ afọwọṣe peptide sintetiki ti homonu somatostatin, o jẹ afọwọṣe somatostatin ti n ṣiṣẹ pipẹ ti itọkasi fun iṣakoso aami aisan ni acromegaly ati awọn èèmọ gastroenteropancreatic.Awọn lilo agbara miiran labẹ iwadii pẹlu àtọgbẹ, psoriasis ati arun Alṣheimer.Octreotide Acetate (Sandostatin) jẹ afọwọṣe peptide sintetiki ti homonu somatostatin.Awọn iṣe rẹ pẹlu idinamọ ti yomijade pituitary ti homonu idagba ati idinamọ ti yomijade sẹẹli islet pancreatic ti hisulini ati glucagon.Ko dabi somatostatin, eyiti o ni idaji-aye pilasima ti iṣẹju diẹ, Octreotide ni imukuro pilasima idaji-aye ti wakati 1 si 2.Iyọkuro oogun naa jẹ kidirin ni akọkọ.Octreotide dinku motility ikun ati idilọwọ ihamọ ti gallbladder.

Awọn oogun peptide Novartis Sandostatin (Octreotide Acetate), jẹ awọn itọsẹ somatostatin octapeptide ti ara sintetiki, o ṣe itọju ipa elegbogi bii ti somatostatin, ati pe ipa naa jẹ pipẹ.Awọn itọkasi fun Octreotide Acetate pẹlu acromegaly;Ilọkuro awọn aami aisan ati awọn ami ti o ni nkan ṣe pẹlu iṣẹ-ṣiṣe gastroenteropancreatic endocrine neoplasia;Ati ipa ni Awọn Tumor Carcinoid ti n ṣafihan pẹlu iṣọn carcinoid, awọn èèmọ VIP, ati awọn èèmọ glucagon.Ni afikun, Octreotide Acetate fun gastrinomas / Zollinger-Ellison dídùn (nigbagbogbo ni apapo pẹlu proton fifa inhibitors tabi H2 receptor blockers), Insulinomas (idena iṣaaju ti hypoglycemia ati itọju suga ẹjẹ deede), oṣuwọn iwulo ti homonu idagba ti o tu tumo ifosiwewe jẹ nipa 50%.

Octreotide Acetate jẹ oogun iṣeduro ilera ti orilẹ-ede B oogun, eyiti o jẹ itọsẹ octapeptide adayeba sintetiki ti somatostatin, ni akawe pẹlu somatostatin adayeba, idaji-aye ti somatostatin ti han ni pẹ ati pe o ni awọn ipa elegbogi kanna, pẹlu idinamọ iṣẹ homonu idagba, idinamọ. ti inu acid, enzymu pancreatic, glucagon ati yomijade insulin, ati idinku sisan ẹjẹ visceral, dinku motility ikun ati inu.Ti a ṣe afiwe pẹlu somatostatin abinibi, octreotide ni igbesi aye idaji gigun, o yan diẹ sii fun idinamọ ti yomijade homonu idagba ju fun idinamọ ti yomijade hisulini, ati pe ko fa isọdọtun hypersecretion ti homonu naa.1, Iṣẹ abẹ iṣakoso tabi itọju ailera ko le ṣakoso arun naa ni deede ni awọn alaisan ti o ni awọn aami aiṣan acromegaly ati dinku homonu idagba ti alaisan (GH) insulin-bi ifosiwewe idagbasoke -1 (1GF-1) awọn ipele pilasima.Sandostatin le tun ṣee lo lati tọju awọn alaisan ti o ni acromegaly ti ko lagbara tabi ti ko fẹ lati ṣe iṣẹ abẹ, tabi lati tọju awọn alaisan ti o ni acromegaly ti ko tii ni itọju ailera itankalẹ.2. Ilọkuro awọn aami aisan ti o ni nkan ṣe pẹlu iṣẹ-ṣiṣe gastroenteropancreatic (GEP) awọn èèmọ endocrin gẹgẹbi awọn èèmọ carcinoid pẹlu awọn ifarahan aisan carcinoid.Sandostatin kii ṣe oogun egboogi-akàn ati pe ko ṣe arowoto awọn alaisan wọnyi.3, Idena awọn ilolu lẹhin iṣẹ abẹ pancreatic.4, Awọn alaisan ti ẹdọ cirrhosis ti o ni ẹjẹ inu-esophageal variceal ẹjẹ ti o ṣẹlẹ nipasẹ itọju pajawiri, hemostasis ati idena ti rebleeding, Sandostatin yẹ ki o ni idapo pẹlu endoscopic sclerotherapy ati awọn itọju pataki miiran.

83150-76-9 - Aabo:

Awọn ipa ẹgbẹ ti ọja yii jẹ Irora Inu, Distension inu, gbuuru, steatorrhea;Ibiyi ti Gallstone;Ifarada glukosi le dinku tabi buru si ni ipele ibẹrẹ ti itọju, lẹhinna o le ni ilọsiwaju;Ohun elo igba pipẹ laisi iṣelọpọ antibody endogenous, ko si isọdọtun ti o han gedegbe tabi aiṣe ikolu nigbati oogun naa duro tabi dinku ni iyara.2 ~ 8 deg C fun ipamọ igba pipẹ.

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