Olmesartan Medoxomil CAS 144689-63-4 Mimọ>99.5% (HPLC) Ile-iṣẹ API
Ipese Kemikali Ruifu Olmesartan Medoxomil Awọn agbedemeji pẹlu Didara to gaju:
4,5-Dimethyl-1,3-Dioxol-2-Ọkan (DMDO) CAS 37830-90-3
4-Chloromethyl-5-Methyl-1,3-Dioxol-2-Ọkan (DMDO-Cl) CAS 80841-78-7
Ethyl 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylate CAS 144689-93-0
Diethyl 2-Propyl-1H-Imidazole-4,5-Dicarboxylate CAS 144689-94-1
Triyl Olmesartan Ethyl Ester CAS 144690-33-5
Triyl Olmesartan Acid CAS 761404-85-7
N2-Trityl Olmesartan Acid CAS 752179-89-8
Triyl Olmesartan Medoxomil CAS 144690-92-6
Olmesartan Medoxomil CAS 144689-63-4
Orukọ Kemikali | Olmesartan Medoxomil |
Awọn itumọ ọrọ sisọ | 4- (1-Hydroxy-1-methylethyl) -2-propyl-1-[2'- (2H-tetazol-5-yl) [1,1'-biphenyl] -4-yl] methyl] -1H- imidazole-5-carboxylic Acid (5-Methyl-2-oxo-1,3-dioxol-4-yl) methyl Ester;CS-866 |
Nọmba CAS | 144689-63-4 |
NỌMBA CAT | RF-PI1730 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
Fọọmu Molecular | C29H30N6O6 |
Òṣuwọn Molikula | 558.60 |
Ojuami Iyo | 180 ℃ (oṣu kejila) |
Omi Solubility | Ailopin ninu Omi;Die-die Soluble ni DMSO |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Funfun to Fere White Cyrstalline Powder |
Idanimọ | IR, HPLC, UV: Gbọdọ ni ibamu si Iwọn Itọkasi |
Mimọ / Analysis Ọna | > 99.5% (HPLC lori Anhydrous ati Ipilẹ Ọfẹ) |
Pipadanu lori Gbigbe | <0.50% |
Aloku lori Iginisonu | <0.10% |
Awọn nkan ti o jọmọ | |
Olmesartan RRT 0.2 | <0.50% |
Olmesartan Medoxoil Iṣajọpọ Ajọpọ A. RRT 0.7 | <0.20% |
Olifinic aimọ RRT 1.6 | <0.50% |
N-Alkyl Aimọ RRT 3.4 | <0.10% |
Eyikeyi Iwa Aimọ | <0.10% |
Lapapọ Awọn Aimọ | <0.50% |
Awọn irin Heavy (gẹgẹbi Pb) | <10ppm |
pH ti Solusan (2%, W/V) | 4.5 si 6.5 |
Igbeyewo Standard | Standard Enterprise;USP Standard |
Lilo | API |
Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin
Olmesartan Medoxomil (CS-866) (CAS: 144689-63-4) jẹ agbara ati yiyan angiotensin II iru 1 (AT (1)) antagonist olugba pẹlu IC50 ti 66.2 μM., ti a lo ninu itọju titẹ ẹjẹ giga.Ti a lo bi egboogi-haipatensonu.Olmesartan ṣiṣẹ nipa didi asopọ ti angiotensin II si awọn olugba AT1 ni iṣan iṣan.Nipa didi idinamọ dipo iṣelọpọ ti angiotensin II, Olmesartan ṣe idiwọ awọn esi ilana odi lori yomijade renin.Olmesartan Medoxomil jẹ oogun pro-oògùn ti a ti sọ di-esterified si metabolite ti nṣiṣe lọwọ, olmesartan.Olmesartan Medoxomil ti ṣe ifilọlẹ ni AMẸRIKA bi Benicar, itọju ti a nṣakoso ẹnu fun haipatensonu.