Olopatadine Hydrochloride Intermediate CAS 27710-82-3 Mimọ>99.0% (HPLC)
Olupese asiwaju ti Olopatadine Hydrochloride Intermediates
Olopatadine Hydrochloride CAS 140462-76-6
Isoxepac CAS 55453-87-7
[3- (Dimethylamino) propyl] triphenylphosphonium Bromide Hydrobromide CAS 27710-82-3
Please Contact: alvin@ruifuchem.com
| Orukọ Kemikali | [3- (Dimethylamino) propyl] triphenylphosphonium Bromide Hydrobromide |
| Awọn itumọ ọrọ sisọ | (3-Dimethylaminopropyl) triphenylphosphonium Bromide HBr |
| Nọmba CAS | 27710-82-3 |
| NỌMBA CAT | RF2698 |
| Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
| Fọọmu Molecular | C23H28Br2NP |
| Òṣuwọn Molikula | 509.27 |
| Ojuami Iyo | 283.0 ~ 285.0 ℃ |
| Iduroṣinṣin | Hygroscopic |
| Solubility | Chloroform (Diẹ), kẹmika (Diẹ) |
| Brand | Ruifu Kemikali |
| Nkan | Awọn pato |
| Ifarahan | Funfun to Pa-White Crystal Powder |
| Mimọ / Analysis Ọna | > 99.0% (HPLC) |
| Aseyori / Analysis Ọna | > 99.0% (Titration) |
| Pipadanu lori Gbigbe | <0.50% |
| Aimọ Kanṣoṣo | <0.50% |
| Lapapọ Awọn Aimọ | <1.00% |
| 1 H NMR julọ.Oniranran | Ni ibamu Pẹlu Be |
| Igbeyewo Standard | Standard Enterprise |
| Lilo | Agbedemeji ti Olopatadine Hydrochloride (CAS: 140462-76-6) |
Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin
Bawo ni lati Ra?Please contact: sales@ruifuchem.com or alvin@ruifuchem.com
15 Ọdun Iriri?A ni diẹ sii ju ọdun 15 ti iriri ni iṣelọpọ ati okeere ti ọpọlọpọ awọn agbedemeji elegbogi didara tabi awọn kemikali to dara.
Awọn ọja akọkọ?Ta si ọja ile, North America, Europe, India, Russia, Korea, Japanese, Australia, ati be be lo.
Awọn anfani?Didara to gaju, idiyele ifarada, awọn iṣẹ alamọdaju ati atilẹyin imọ-ẹrọ, ifijiṣẹ yarayara.
DidaraIdaniloju?Eto iṣakoso didara to muna.Awọn ohun elo ọjọgbọn fun itupalẹ pẹlu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, bbl
Awọn apẹẹrẹ?Pupọ awọn ọja pese awọn apẹẹrẹ ọfẹ fun igbelewọn didara, idiyele gbigbe yẹ ki o san nipasẹ awọn alabara.
Ayẹwo ile-iṣẹ?Ayẹwo ile-iṣẹ kaabo.Jọwọ ṣe ipinnu lati pade ni ilosiwaju.
MOQ?Ko si MOQ.Ibere kekere jẹ itẹwọgba.
Akoko Ifijiṣẹ? Ti o ba wa laarin ọja iṣura, iṣeduro ifijiṣẹ ọjọ mẹta.
Gbigbe?Nipa Express (FedEx, DHL), nipasẹ Air, nipasẹ Okun.
Awọn iwe aṣẹ?Lẹhin iṣẹ tita: COA, MOA, ROS, MSDS, ati bẹbẹ lọ ni a le pese.
Aṣa Synthesis?Le pese awọn iṣẹ iṣelọpọ aṣa lati baamu awọn iwulo iwadii rẹ dara julọ.
Awọn ofin sisan?Iwe risiti Proforma yoo firanṣẹ ni akọkọ lẹhin ijẹrisi aṣẹ, ti ifi alaye banki wa sinu.Isanwo nipasẹ T/T (Telex Gbigbe), PayPal, Western Union, ati bẹbẹ lọ.
[3- (Dimethylamino) propyl] triphenylphosphonium Bromide Hydrobromide (CAS: 27710-82-3) jẹ agbedemeji ti Olopatadine Hydrochloride (CAS: 140462-76-6).Olopatadine Hydrochloride jẹ oogun egboogi-egbogi.O ni awọn ipa meji ti idinamọ itusilẹ ti histamini ati yiyan atako awọn olugba HI, ati pe ko ni idinamọ eto aifọkanbalẹ aarin ati awọn ipa ẹgbẹ majele ọkan ti o wọpọ pẹlu awọn oogun antiallergic olugba olugba HI.Olopatadine Hydrochloride ko le ṣe idiwọ itusilẹ histamini nikan lati awọn sẹẹli mast, ṣugbọn tun tako awọn olugba H1 ni yiyan, ati pe ko ni ipa lori awọn olugba adrenergic α, awọn olugba dopamine, ati awọn olugba M1 ati M2.Lara wọn, awọn ipa ẹgbẹ ti eto aifọkanbalẹ aarin jẹ diẹ, iran tuntun ti awọn oogun antiallergic ti yiyan.Olopatadine jẹ alagbara, antagonist ti o yan ti H1 histamine receptor (Ki = 16-41.1 nM), pẹlu awọn affinities kekere pupọ fun awọn olugba H2 ati H3 (Ki = 43.4 ati 172 μM, lẹsẹsẹ).O ṣe idiwọ iyipada phosphoinotide ti histamini ṣe ni awọn sẹẹli ti o ya sọtọ (IC50 = 9.5-39.9 nM) ati idilọwọ anafilasisi awọ-ara palolo ninu awọn eku (ED50 = 49 μg/kg) ati bronchoconstriction anafilactic ninu awọn ẹlẹdẹ Guinea (ID50g = 30 ).Olopatadine munadoko ninu atọju rhinitis inira ati conjunctivitis.O tun dinku itch ni awọn alaisan ti o ni iṣakoso urticaria onibaje ti iṣakoso daradara.Ninu eniyan, antihistamine yii ko fa ailagbara imọ-ọkan tabi psychomotor ni awọn iwọn itọju ailera.
