Omeprazole Sulfide CAS 73590-85-9 Mimọ> 99.0% (HPLC) Ile-iṣẹ
Ruifu Kemikali Ipese Omeprazole Intermediates Pẹlu Giga Mimo
Omeprazole CAS 73590-58-6
Omeprazole Hydroxy Compound CAS 86604-78-6
Omeprazole Chloride Apapo CAS 86604-75-3
Omeprazole Sulfide CAS 73590-85-9
2-Mercapto-5-Methoxybenzimidazole CAS 37052-78-1
2-Cyano-3-Methylpyridine CAS 20970-75-6
2,3,5-Trimethylpyridine CAS 695-98-7
Orukọ Kemikali | Omeprazole Sulfide |
Awọn itumọ ọrọ sisọ | Ufiprazole;Omeprazole Sulfur Eteri;Esomeprazole EP Aimọ C;Omeprazole EP Aimọ C;5-Methoxy-2-[[(4-Methoxy-3,5-Dimethyl-2-Pyridyl)methyl]thio] benzimidazole;5-Methoxy-2-{[(4-Methoxy-3,5-Dimethyl-2-Pyridinyl)methyl]thio}-1H-Benzimidazole |
Nọmba CAS | 73590-85-9 |
NỌMBA CAT | RF-PI1914 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
Ilana molikula | C17H19N3O2S |
Òṣuwọn Molikula | 329.42 |
Ojuami Iyo | 122.0 si 126.0 ℃ |
Solubility | Tiotuka ni kẹmika |
iwuwo | 1,28 ± 0,10 g / cm3 |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Funfun si Paa-White Powder tabi kirisita |
Mimọ / Analysis Ọna | > 99.0% (HPLC) |
Pipadanu lori Gbigbe | <1.00% |
Aloku lori Iginisonu | <0.20% |
Awọn irin Heavy (gẹgẹbi Pb) | <20ppm |
Nikan Aimọ | <0.50% |
Lapapọ Awọn Aimọ | <1.00% |
Infurarẹẹdi julọ.Oniranran | Ni ibamu si Eto |
Proton NMR julọ.Oniranran | Ni ibamu si Eto |
Igbeyewo Standard | Standard Enterprise |
Lilo | Aarin ti Omeprazole / Esomeprazole |
Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin
Omeprazole Sulfide (CAS: 73590-85-9) jẹ agbedemeji ti a lo ninu iṣelọpọ awọn inhibitors proton pump inhibitors, Omeprazole (CAS: 73590-58-6) ati Esomeprazole (CAS: 119141-88-7), Esomeprazole Sodium ( CAS: 161796-78-7).Gẹgẹbi ọja ibajẹ, o royin pe o jẹ oludanukokoro ti o n ṣiṣẹ taara ti cytochrome P450 2C19 ninu awọn microsomes ẹdọ ti eniyan ti a dapọ (IC50 = 9.7 μM).Omeprazole Sulfide jẹ metabolite ti Omeprazole.Esomeprazole Sodium jẹ fọọmu iyọ iṣuu soda ti esomeprazole.O jẹ oogun egboogi-ọgbẹ ti o wọpọ ti a lo, eyiti a kọkọ ni aṣeyọri nipasẹ ile-iṣẹ Swedish Astra Zeneca ni akọkọ.O jẹ ti proton fifa inhibitor.Inhibitor fifa proton jẹ yiyan akọkọ fun atọju ọgbẹ peptic, arun gastro-esophageal reflux ati awọn arun ti o ni ibatan acid.Lọwọlọwọ ti a nlo ni ile-iwosan PPI ni awọn oriṣi marun: Omeprazole, Lansoprazole, Rabeprazole, Pantoprazole ati Esomeprazole.Gẹgẹbi PPI akọkọ, ipa oogun omeprazole ni ṣiṣe itọju awọn arun ti o ni ibatan si acid ni a ti mọ jakejado.Esomeprazole jẹ S-isomer ti Omeprazole, eyiti o le dinku yomijade acid inu nipasẹ ọna ṣiṣe ifọkansi kan pato.O jẹ onidalẹkun kan pato fun oludena fifa proton ninu sẹẹli parietal.Nitori anfani ijẹ-ara ti esomeprazole, o ni bioavailability ti o ga julọ ati awọn elegbogi elegbogi deede diẹ sii ju ẹlẹgbẹ rẹ Omeprazole Sodium, jijẹ oogun ti o de ọdọ fifa proton.Ipa rẹ ti iṣakoso acid inu jẹ dara julọ ju awọn oludena fifa proton miiran bii Lansoprazole, Pantoprazole, ati Rabeprazole.