Palbociclib Intermediate CAS 1016636-76-2 Mimọ>99.0% (HPLC) Ile-iṣẹ
Ipese Kemikali Ruifu Palbociclib Awọn agbedemeji ibatan:
Palbociclib CAS 571190-30-2
5-Bromo-2,4-Dichloropyrimidine CAS 36082-50-5
5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8
tert-Butyl 4-(6-Nitropyridin-3-yl) piperazine-1-Carboxylate CAS 571189-16-7
tert-Butyl 4-(6-Amino-3-Pyridyl)piperazine-1-Carboxylate CAS 571188-59-5
6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7(8H) -ọkan CAS 1016636-76-2
2-Chloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pyrimidin-7-ọkan CAS 1013916-37-4
Orukọ Kemikali | 6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7(8H) -ọkan |
Awọn itumọ ọrọ sisọ | Palbociclib-Pb3 |
Nọmba CAS | 1016636-76-2 |
NỌMBA CAT | RF-PI1849 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
Ilana molikula | C13H13BrClN3O |
Òṣuwọn Molikula | 342.63 |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Funfun to Light Yellow Powder |
Mimọ / Analysis Ọna | > 99.0% (HPLC) |
Awọn nkan ti o jọmọ | <1.00% |
Pipadanu lori Gbigbe | <0.50% |
Omi (KF) | <0.50% |
Igbeyewo Standard | Standard Enterprise |
Lilo | Agbedemeji ti Palbociclib (CAS: 571190-30-2) |
Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin
6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d] pyrimidin-7 (8H) -ọkan (CAS: 1016636-76-2) jẹ agbedemeji ti Palbociclib (CAS: 571190- 30-2).Palbociclib jẹ oogun fun itọju ER-positive ati HER2-negative akàn igbaya ti o ni idagbasoke.Palbociclib jẹ oludena yiyan ti awọn kinases ti o gbẹkẹle cyclin CDK4 ati CDK6.Ni Oṣu Kẹta Ọjọ 3, Ọdun 2015, US FDA fọwọsi Pfizer's Palbociclib (orukọ iṣowo: Ibrance) fun itọju ti akàn igbaya to ti ni ilọsiwaju/metastatic ninu awọn obinrin postmenopausal.Palbociclib jẹ oludena CDK4/6 akọkọ lati gba ifọwọsi FDA.