Palonosetron Hydrochloride CAS 135729-62-3 Mimo>99.0% (HPLC) (T) Aworan Ifihan Factory API

Palonosetron Hydrochloride CAS 135729-62-3 Mimọ>99.0% (HPLC) (T) API Factory

Apejuwe kukuru:

Orukọ Kemikali: Palonosetron Hydrochloride

CAS: 135729-62-3

Irisi: Funfun tabi Paa-White Crystalline Powder

Mimọ:> 99.0% (HPLC) (T)

Palonosetron Hydrochloride jẹ alagbara ti o ga julọ, yiyan ati ti nṣiṣe lọwọ ẹnu antagonist olugba olugba 5-HT3 ti a lo ninu idena ati itọju ti ọgbun ati eebi ti o fa kimoterapi (CINV).Antiemetic.

Olubasọrọ: Dokita Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

Inquiry: alvin@ruifuchem.com

Fi imeeli ranṣẹ si wa

Alaye ọja

Jẹmọ Products

ọja Tags

Apejuwe:

Ipese Iṣowo Palonosetron Hydrochloride ati Awọn agbedemeji ibatan:
(S) -1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS: 85977-52-2
(R) -1,2,3,4-Tetrahedro-1-Naphthoic Acid CAS: 23357-47-3
(S)-3-Aminoquinuclidine Dihydrochloride CAS: 119904-90-4
3-Quinuclidinone Hydrochloride CAS: 1193-65-3
1-Naphthoic Acid CAS: 86-55-5
Palonosetron Hydrochloride CAS: 135729-62-3 API

Kemikali Properties:

Orukọ Kemikali	Palonosetron Hydrochloride
Awọn itumọ ọrọ sisọ	Palonosetron HCl;(S, S) - Palonosetron Hydrochloride;RS-25259;RS25259 197;(S) -2- ((S) -Quinuclidin-3-yl) -2,3,3a,4,5,6-Hexahydro-1H-Benzo [de] isoquinolin-1-ọkan Hydrochloride;(3aS) -2- (3S) -1-Azabicyclo [2.2.2] oct-3-yl-2,3,3a,4,5,6-Hexahydro-1H-benz[de] isoquinolin-1-ọkan Hydrochloride ;Aloxi;Onicit
Nọmba CAS	135729-62-3
NỌMBA CAT	RF-API03
Iṣura Ipo	Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu
Fọọmu Molecular	C19H24N2O·HCl
Òṣuwọn Molikula	332.87
Ipo lati Yẹra	Ooru kókó
Ojuami Iyo	307 ℃ (oṣu kejila)
Solubility ninu Omi	Soluble patapata ninu Omi
Solubility	Tiotuka pupọ ni Ethanol
Sowo otutu	Ibaramu otutu
COA & MSDS	Wa
Brand	Ruifu Kemikali

Awọn pato:

Nkan	Awọn pato
Ifarahan	Funfun tabi Pa-White Crystalline Powder
Palonosetron Hydrochloride	> 99.0% (HPLC) (T)
Yiyi pato [α] 20/D	-98.0°～-104.0°
Idanimọ	Ṣafikun BiI7K4, Ṣe ipilẹṣẹ Idajo Yellow Orange
Idanimọ	TLC ni ibamu pẹlu nkan Itọkasi
Idanimọ	IR Ni ibamu pẹlu Standard IR
Idanimọ	Idanimọ bi kiloraidi
Solubility	Tiotuka larọwọto ninu omi, tiotuka diẹ ninu methanol, tiotuka die-die ni ethanol, ailesoju ninu acetone
wípé ati Awọ ti Solusan	O pọju.Yellow No.. 2 Standard Awọ Solusan
pH Vaule	4.5 ~ 6.5 (10mg / milimita)
Awọn ipese ti o jọmọ
Apapo A ti o jọmọ (KO)	<0.10%
Apapo B ti o jọmọ (Ene-NO)	<0.10%
Agbo ti o jọmọ C (S,R)	<0.10%
Agbo ti o jọmọ D (R,S)	<0.50%
Palonosetron Enantiomer	<0.10%
Agbo ti o jọmọ E (3-Ene)	<0.50%
Nikan Aisọye Aimọ	<0.10%
Awọn ohun elo ti o ku
Ethanol	<3000ppm
Tetrahydrofuran	<5000ppm
DMF	<880ppm
Hexane deede	<290ppm
Methyl Ọtí	<3000ppm
Isopropanol	<5000ppm
Methylbenzene	<890ppm
Omi	<0.30%
Aloku lori Iginisonu	<0.20%
Pipadanu lori Gbigbe	<1.00%
Awọn irin Heavy	<10ppm
Igbeyewo Standard	Orilẹ Amẹrika Pharmacopoeia (USP);European Pharmacopoeia (EP)
Lilo	Palonosetron Hydrochloride API;5-HT3 alatako;CINV

Package & Ibi ipamọ:

Package: Igo, Ilu paali, 25kg / Ilu, tabi gẹgẹbi ibeere alabara.

Ibi ipamọ:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.

Awọn anfani:

FAQ:

Ohun elo:

Palonosetron Hydrochloride (CAS: 135729-62-3) jẹ oogun kan lati dena ọgbun ati eebi, eyiti o jẹ iru tuntun ti o yan gaan, affinity 5-HT3 antagonist olugba giga ti o le dènà eebi reflex aarin awọn neurons agbeegbe presynaptic 5-HT.Idunnu olugba taara ni ipa lori eto aifọkanbalẹ aarin ni 5-HT.Idunnu olugba ti nfa ti ipilẹṣẹ nipasẹ ipa ti iṣan afferent vagal lẹhin agbegbe, didi awọn opin nafu ara vagus ninu ikun, idilọwọ awọn ifihan agbara si 5-HT.Agbegbe ti nfa olugba le dinku iṣẹlẹ ti ríru ati eebi.Aarin ile-iwosan fun itọju ti kimoterapi emetogenic nla ti o fa inu ríru idaduro ati eebi.Nitori ipa itọju giga rẹ, ipa ẹgbẹ kekere, igbesi aye idaji gigun (nipa awọn wakati 40), iwọn lilo kekere, ati bẹbẹ lọ, o ti fa ifojusi pupọ.

Pẹlu 1,2,3,4-Tetrahydro-1-Naphthoic Acid bi ohun elo ibẹrẹ, pipin, amination, idinku, cyclization, iyọ ti palonosetron hydrochloride granisetron.Awọn ijinlẹ ile-iwosan fihan pe palonosetron le ṣee lo lailewu pẹlu awọn corticosteroids, awọn analgesics, antiemetics, antispasmodics ati anticholinergic drugs bi awọn ohun elo ibẹrẹ, pipin, amination, idinku, cyclization, iyọ ti palonosetron hydrochloride granisetron.