Paxlovid Boceprevir Intermediate CAS 565456-77-1 Assay ≥99.0%
Ipese Iṣowo PF-07321332 Awọn agbedemeji ti o jọmọ Paxlovid pẹlu Didara Giga
L-tert-Leucine (H-Tle-OH) CAS 20859-02-3
Caronic Anhydride CAS 67911-21-1
(1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-Carboxylic Acid Methyl Ester Hydrochloride 565456-77-1
Methyl (S) -2- (Boc-amino) -3- [(S) -2-oxo-3-pyrrolidinyl] propanoate CAS 328086-60-8
6,6-Dimethyl-3-azabicyclo[3.1.0] hexane CAS 943516-54-9
Orukọ Kemikali | (1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0] hexane-2-Carboxylic Acid Methyl Ester Hydrochloride |
Awọn itumọ ọrọ sisọ | Methyl (1R,2S,5S) -6,6-dimethyl-3-azabicyclo[3.1.0] hexane-2-carboxylate Hydrochloride |
Nọmba CAS | 565456-77-1 |
NỌMBA CAT | RF-PI318 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
Fọọmu Molecular | C9H15NO2.ClH |
Òṣuwọn Molikula | 205.683 |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Funfun to Pa-White Powder |
Idanimọ A | IR: Iru si nkan Itọkasi |
Idanimọ B | Akoko Idaduro: Iru si nkan Itọkasi |
Enantomer | ≤0.15% |
Aimọ ti o jọmọ (nipasẹ HPLC) | |
Aimọ Aimọ | ≤0.20% |
Lapapọ Awọn Aimọ | ≤1.0% |
Omi | ≤0.50% |
Aloku lori Iginisonu | ≤0.10% |
Awọn irin Heavy | ≤20ppm |
Ayẹwo | ≥99.0% |
Igbeyewo Standard | Standard Enterprise |
Lilo | Agbedemeji ti PF-07321332 Paxlovid (CAS 2628280-40-8) ati Boceprevir (CAS 394730-60-0) |
Package: Igo, apo apamọwọ Aluminiomu, ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.
(1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-Carboxylic Acid Methyl Ester Hydrochloride (CAS 565456-77-1) jẹ itọsẹ azabicyclohexane ti a lo ninu igbaradi ti jedojedo C kokoro (HCV) NS3 serine protease inhibitor.O jẹ agbedemeji ti PF-07321332 Paxlovid (CAS 2628280-40-8) ati Boceprevir (CAS 394730-60-0).PF-07321332 jẹ oludaniloju to lagbara ati ti nṣiṣe lọwọ SARS-CoV 3C-like protease (3CLPRO).Awọn ibi-afẹde PF-07321332 si ọlọjẹ SARS-CoV-2 ati pe o le ṣee lo fun iwadii COVID-19.Boceprevir (INN, orukọ iṣowo Victrelis) jẹ inhibitor protease ti a lo bi itọju fun arun jedojedo C genotype 1. O sopọ mọ aaye 3 NS3 (HCV) ti kii ṣe ipilẹ ti HCV.Schering-Plough ni idagbasoke rẹ, ṣugbọn Merck ti ni idagbasoke ni bayi lati igba ti Schering ti gba ni ọdun 2009. FDA fọwọsi ni May 13, 2011.