Pyridine-3-Sulfonyl Chloride CAS 16133-25-8 Mimọ ≥98.5% (GC) Vonoprazan Fumarat Factory Intermediate Factory
Ipese Vonoprazan Fumarate ati ibatan Intermediate
5- (2-Fluorophenyl) pyrrole-3-Carboxaldehyde CAS 881674-56-2
Pyridine-3-Sulfonyl kiloraidi CAS 16133-25-8
Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2
| Orukọ Kemikali | Pyridine-3-Sulfonyl kiloraidi |
| Awọn itumọ ọrọ sisọ | 3-Pyridinesulfonyl kiloraidi;3-Pyridylsulfonyl kiloraidi;m-Pyridinesulfonyl kiloraidi;Piperidine-3-Sulfonylchloride |
| Nọmba CAS | 16133-25-8 |
| NỌMBA CAT | RF-PI540 |
| Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
| Fọọmu Molecular | C5H4ClNO2S |
| Òṣuwọn Molikula | 177.61 |
| Brand | Ruifu Kemikali |
| Nkan | Awọn pato |
| Ifarahan | Awọ tabi Bia Yellow Liquid |
| Mimọ / Analysis Ọna | ≥98.5% (GC) |
| Ojuami farabale | 110.0 ~ 112.0 ℃ / 2mm Hg |
| Nikan Aimọ | ≤0.50% |
| Lapapọ Awọn Aimọ | ≤1.5% |
| Igbeyewo Standard | Standard Enterprise |
| Lilo | Agbedemeji ti Vonoprazan Fumarate (CAS: 1260141-27-2) |
Package: Igo, 25kg/Barrel, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin.
Pyridine-3-Sulfonyl Chloride (CAS: 16133-25-8) jẹ agbedemeji ti Vonoprazan Fumarate (CAS: 1260141-27-2).Vonoprazan Fumarate, ti a ṣe awari ati idagbasoke nipasẹ Takeda ati Otsuka, ti fọwọsi nipasẹ PMDA ti Japan ni Oṣu kejila ọdun 2014, ati pe o jẹ itọkasi fun itọju ọgbẹ inu, ọgbẹ duodenal ati reflux esophagitis.Vonoprazan fumarate ni ilana ti aramada ti iṣe ti a pe ni awọn blockers acid competitive potasiomu, eyiti o ṣe idiwọ idinamọ ti awọn ions potasiomu si H +, K +-ATPase (ti a tun mọ ni fifa proton) ni ipele ikẹhin ti yomijade acid inu ninu awọn sẹẹli ti inu.Vonoprazan ko ṣe idiwọ iṣẹ Na +, K + -ATPase paapaa ni awọn ifọkansi awọn akoko 500 ti o ga ju ti awọn iye IC50 wọn lodi si iṣẹ H +, K + -ATPase inu.Pẹlupẹlu, oogun naa ko ni ipa nipasẹ ipo aṣiri ikun, ko dabi awọn PPI.
