(R)-(+) -2-Methyl-CBS-oxazaborolidine;(R) -Me-CBS Catalyst CAS 112022-83-0 Iwa mimọ Opitika ≥98.0%

Ipese Olupese;Didara to gaju ati idiyele ifigagbaga

Sibiesi ayase
(S)-(-) 2-Methyl-CBS-oxazaborolidine;(S) -Me-CBS ayase (bi. 1mol / L ni Toluene);CAS: 112022-81-8
(R)-(+) -2-Methyl-CBS-oxazaborolidine;(R) -Me-CBS ayase (bi. 1mol / L ni Toluene);CAS: 112022-83-0

Sibiesi ayase
Awọn ayase CBS tabi Corey–Bakshi–Shibata ayase jẹ ẹya asymmetric ayase yo lati proline.O wa ọpọlọpọ awọn lilo ni awọn aati Organic gẹgẹbi idinku CBS, awọn aati Diels-Alder ati (3+2) cycloadditions.Proline, ohun elo chiral ti o nwaye nipa ti ara, wa ni imurasilẹ ati olowo poku.O n gbe stereocenter rẹ lọ si ayase eyiti o ni anfani lati wakọ iṣesi Organic ni yiyan si ọkan ninu awọn enantiomers meji ti o ṣeeṣe.Yiyan yiyan jẹ nitori igara sita ni ipo iyipada ti o ndagba fun ọkan enantiomer ṣugbọn kii ṣe fun ekeji.

CBS Catalysts fun Idinku Asymmetric ati Asopọmọra Asymmetric
CBS (Corey-Bakshi-Shibata) ayase oxazaborolidine ti jẹ lilo ni idinku asymmetric ti awọn ketones prochiral.Awọn ohun elo miiran pẹlu iṣelọpọ enantioselective ti α-hydroxy acids, α-amino acids, C2-symmetrical ferrocenyl diols, ati propargyl alcohols.

(R) - (+) -2-Methyl-CBS-oxazaborolidine (ca. 1mol/L ni Toluene) CAS: 112022-83-0 le ṣee lo bi apanirun ni idinku asymmetric borane ti awọn ketones perfluoroalkyl.Awọn ohun elo miiran pẹlu iṣelọpọ enantioselective ti α-hydroxy acids, α-amino acids, C2 symmetrical ferrocenyl diols, ati propargyl alcohols.O tun lo ni idinku desymmetry ti o yori si (S) -4-hydroxycyclohexenone.O wulo ni iṣelọpọ awọn ohun elo stereospecific gẹgẹbi α-hydroxy acids, α-amino acids, awọn diols ferrocenyl symmetrical ati awọn oti propargyl.

(R)-(+) -2-Methyl-CBS-oxazaborolidine (ca. 1mol/L ni Toluene) CAS: 112022-83-0 jẹ ẹya organoboron catalyst ti o ti wa ni lo ninu Organic kolaginni.Iyasọtọ yii, ti o dagbasoke nipasẹ Itsuno ati Elias James Corey, jẹ ipilẹṣẹ nipasẹ alapapo (R)-(+)-2- (diphenylhydroxymethyl) pyrrolidine pẹlu trimethylboroxine tabi methylboronic acid.O jẹ ohun elo ti o tayọ fun iṣelọpọ ti awọn ọti-lile ni ipin enantiomeric giga.Ni gbogbogbo, 2-10 mol% ti ayase yii ni a lo pẹlu borane-tetrahydrofuran (THF), borane-dimethylsulfide, borane-N, N-diethylaniline, tabi diborane gẹgẹbi orisun borane.Idinku Enantioselective nipa lilo chiral oxazaborolidine catalysts ti a ti lo ni iṣelọpọ ti awọn oogun iṣowo bii ezetimibe ati aprepitant.