Rabeprazole Sodium CAS 117976-90-6 Mimọ>99.5% (HPLC) Ile-iṣẹ API
Ruifu Kemikali Ipese Rabeprazole Sodium Intermediates
Rabeprazole iṣuu soda CAS 117976-90-6
Rabeprazole Hydroxy Apapo CAS 675198-19-3
Rabeprazole Chloride Apapo CAS 153259-31-5
Orukọ Kemikali | Rabeprazole iṣuu soda |
Awọn itumọ ọrọ sisọ | 2- ([4- (3-Methoxypropoxy) -3-Methylpyridin-2-yl] methylsulfinyl -1H-Benzo [d] imidazole;Pariprazole |
Nọmba CAS | 117976-90-6 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
Fọọmu Molecular | C18H20N3NaO3S |
Òṣuwọn Molikula | 381.42 |
Ojuami Iyo | 140.0 ~ 141.0 ℃ |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Funfun lati Didi-Pale Yellow Crystal tabi Lulú;Hygroscopic |
Infurarẹẹdi julọ.Oniranran | Ni ibamu si Eto |
Proton NMR julọ.Oniranran | Ni ibamu si Eto |
ICP | Jẹrisi paati iṣuu soda |
Solubility | Tiotuka patapata ni Omi;Tiotuka pupọ ni Ethanol, Chloroform;Tiotuka ni kẹmika |
pH | 9.5 ~ 12.0 |
Pipadanu lori Gbigbe | <1.00% |
Awọn irin Heavy | <20ppm |
Awọn nkan ti o jọmọ | (HPLC) |
Aimọ́ A | <0.80% |
Àìsọ pàtó | <0.20% |
Lapapọ Awọn Aimọ | <1.00% |
Awọn ohun elo ti o ku | (GC) |
Methylene kiloraidi | <600ppm |
Ethanol | <5000ppm |
Isopropyl Eteri | <5000ppm |
Acetone | <5000ppm |
Makirobia Ifilelẹ | |
Iwọn Aerobe | ≤1000CFU/g |
Mold ati Yeasts Ka | ≤100CFU/g |
E. Kọli | Ko si fun giramu kan |
Mimọ / Analysis Ọna | > 99.5% (HPLC, ipilẹ gbigbe) |
Igbeyewo Standard | Standard Enterprise |
Lilo | API fun Anti-Ulcer |
Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin
Sodium Rabeprazole (CAS: 117976-90-6) jẹ inhibitor fifa proton ti o dinku iṣelọpọ acid inu ninu ikun.O ni awọn lilo iṣoogun lọpọlọpọ: iṣakoso awọn ipo ti o kan iṣelọpọ acid inu pupọ (fun apẹẹrẹ Zollinger-Ellison syndrome), awọn ipo ti o buru si nipasẹ acid inu (fun apẹẹrẹ awọn ọgbẹ inu ikun), ati awọn ipo ti o kan ifihan gigun si acid inu (fun apẹẹrẹ. aisan gastroesophageal reflux symptomatic).Rabeprazole tun wulo lẹgbẹẹ itọju apakokoro fun itọju pathogen Helicobacter pylori, eyiti bibẹẹkọ ṣe rere ni awọn agbegbe ekikan.Nitorinaa, Rabeprazole Sodium jẹ ifọwọsi FDA fun itọju ti GERD aami-aisan ninu awọn ọdọ ati awọn agbalagba, iwosan ọgbẹ duodenal ninu awọn agbalagba, imukuro Helicobacter pylori, ati awọn ipo aṣiri pathologic.Iṣuu soda Rabeprazole dinku iṣelọpọ acid ninu ikun nipasẹ didi H+/K+ATPase inu (hydrogen-potassium adenosine triphosphatase) ni aaye ikọkọ ti sẹẹli parietal inu.