Ramelteon Acrylonitrile CAS 196597-79-2 Ramelteon Intermediate Purity>98.0% (HPLC)
Asiwaju Olupese ati Olupese, Intermediates ti Ramelteon
Ramelteon (TAK-375) CAS 196597-26-9
2,3-Dihydrobenzofuran CAS 496-16-2
1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-ọkan CAS 196597-78-1
Ramelteon Acrylonitrile CAS 196597-79-2
Despropionyl Ramelteon Hydrochloride CAS 196597-80-5
2- (2,6,7,8-Tetrahydro-1H-Indeno [5,4-b]furan-8-yl)ethanamine Hydrochloride CAS 1053239-39-6
Please contact: alvin@ruifuchem.com
| Orukọ Kemikali | (E)-(1,6,7,8-Tetrahydro-2H-Indeno[5,4-b]furan-8-ylidene) acetonitrile |
| Awọn itumọ ọrọ sisọ | Ramelteon Acrylonitrile;Ramelteon Aimọ 6;Ramelteon Aimọkan B;Ramelteon Cyano Aimọ;(E) -2- (6,7-Dihydro-1H-Indeno [5,4-b]furan-8 (2H) -ylidene) acetonitrile;(2E) -2- (1,2,6,7-Tetrahydrocyclopenta[e] [1] benzofuran-8-ylidene) acetonitrile;(1,2,6,7-Tetrahydro-3-oxa-as-indacen-8-ylidene) -acetonitrile |
| Nọmba CAS | Ọdun 196597-79-2 |
| NỌMBA CAT | RF2886 |
| Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
| Fọọmu Molecular | C13H11NO |
| Òṣuwọn Molikula | 197.23 |
| Ojuami Iyo | 146.0 ~ 151.0 ℃ |
| Ojuami farabale | 392.1± 21.0℃ ni 760 mmHg |
| Oju filaṣi | 165,0 ± 15,9 ℃ |
| iwuwo | 1.321 ± 0,06 g / cm3 |
| HS koodu | 2932999099 |
| Brand | Ruifu Kemikali |
| Nkan | Awọn pato |
| Ifarahan | Funfun to Yellow ri to Powder |
| Mimọ / Analysis Ọna | > 98.0% (HPLC) |
| Pipadanu lori Gbigbe | <1.00% |
| Lapapọ Awọn Aimọ | <2.00% |
| 1 H NMR julọ.Oniranran | Ni ibamu Pẹlu Be |
| Igbeyewo Standard | Standard Enterprise |
| Lilo | Agbedemeji ti Ramelteon (CAS: 196597-26-9) |
Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin
Bawo ni lati Ra?Jọwọ kan siDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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Ayẹwo ile-iṣẹ?Ayẹwo ile-iṣẹ kaabo.Jọwọ ṣe ipinnu lati pade ni ilosiwaju.
MOQ?Ko si MOQ.Ibere kekere jẹ itẹwọgba.
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Aṣa Synthesis?Le pese awọn iṣẹ iṣelọpọ aṣa lati baamu awọn iwulo iwadii rẹ dara julọ.
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(E) (1,6,7,8-Tetrahydro-2H-Indeno [5,4-b]furan-8-ylidene) acetonitrile (CAS: 935-56-8) jẹ agbedemeji ti Ramelteon (CAS: 196597). -26-9).Ramelteon (TAK-375) jẹ agonist olugba olugba melatonin aramada fun eniyan MT1 ati awọn olugba MT2 ati awọn olugba melatonin iwaju ọpọlọ adiye pẹlu Ki ti 14 pM, 112 pM ati 23.1 pM, lẹsẹsẹ.A ṣe atunṣe moleku melatonin nipataki nipa rirọpo nitrogen ti oruka indole pẹlu erogba lati fun oruka indane ati nipa fifi ẹgbẹ 5-methoxyl sinu oruka indole sinu oruka furani ti o lagbara diẹ sii.Yiyan ti ramelteon ti o yọrisi fun olugba MT1 ni igba diẹ sii ju ti olugba MT2 lọ.Ko dabi melatonin, o munadoko diẹ sii ni pilẹṣẹ oorun (iṣẹ MT1) dipo ki o tun iwọn ti sakediani pada (iṣẹ MT2).O han gbangba pe o munadoko diẹ sii ju melatonin ṣugbọn ko ni agbara ju awọn benzodiazepines bi hypnotic kan.Ni pataki, oogun yii ko ni layabiliti afẹsodi (kii ṣe nkan ti iṣakoso).Bi abajade, laipe a ti fọwọsi fun itọju insomnia.
