Remdesivir GS-5734 CAS 1809249-37-3 COVID-19 API Aworan Ifihan Didara Giga

Remdesivir GS-5734 CAS 1809249-37-3 COVID-19 API Didara Giga

Apejuwe kukuru:

Orukọ Kemikali: Remdesivir (GS-5734)

CAS: 1809249-37-3

Irisi: Funfun si Paa-White Ri to Powder

Ayẹwo: 98.0% ~ 102.0%

Remdesivir fun itọju COVID-19

API Didara Giga, Iṣelọpọ Iṣowo

Inquiry: alvin@ruifuchem.com

Fi imeeli ranṣẹ si wa

Alaye ọja

Jẹmọ Products

ọja Tags

Apejuwe:

Olupese Ipese Iṣowo Remdesivir ati Awọn agbedemeji ibatan pẹlu Didara Giga
Remdesivir CAS 1809249-37-3
2-Ethyl-1-butanol CAS 97-95-0
Trimethylsilyl Cyanide CAS 7677-24-9
4-Nitrophenol CAS 100-02-7
2-Ethylbutyl ((S)-(perfluorophenoxy) (phenoxy) phosphoryl) -L-alaninate CAS 1911578-98-7
N-[(S)-(4-nitrophenoxy) phenoxyphosfinyl] -L-Alanine 2-ethylbutyl ester CAS 1354823-36-1
(S)-2-Ethylbutyl 2-Aminopropanoate Hydrochloride CAS 946511-97-3
Remdesivir Metabolite (GS-441524) CAS 1191237-69-0
Remdesivir N-2 Agbedemeji CAS 1191237-80-5
2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5
7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine CAS 937046-98-5
Pyrrolo[1,2-F][1,2,4]Triazin-4-Amine CAS 159326-68-8
4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine CAS 1770840-43-1

Kemikali Properties:

Orukọ Kemikali	Remdesivir
Awọn itumọ ọrọ sisọ	GS-5734;2-ethylbutyl ((S)-((2R,3S,4R,5R))-5- (4-aminopyrrolo [2,1-f][1,2,4]triazin-7-yl) -5-cyano -3,4-dihydroxytetrahydrofuran-2-yl)methoxy) (phenoxy) phosphoryl) -L-alaninate
Nọmba CAS	1809249-37-3
NỌMBA CAT	RF-API96
Iṣura Ipo	Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn ọgọọgọrun Kilogram
Fọọmu Molecular	C27H35N6O8P
Òṣuwọn Molikula	602.58
iwuwo	1,47 ± 0,1 g / cm3
Brand	Ruifu Kemikali

Awọn pato:

Nkan	Awọn pato
Ifarahan	Funfun to Pa-White ri to Powder
Idanimọ A	IR: Iwọn ifasilẹ infurarẹẹdi ti ọja yẹ ki o wa ni ibamu pẹlu ti nkan itọkasi
Idanimọ B	HPLC Idaduro akoko iru si itọkasi nkan na
Yiyi pato	-19.0° ~ -22.0°
Solubility	Solunle ni kẹmika kẹmika, Tiotuka diẹ ninu Ethanol, Itukutu diẹ ninu Acetonitrile, Aifọwọyi Laiṣe ninu Omi
Awọn nkan ti o jọmọ
Eyikeyi Olukuluku aimọ	≤0.10%
Lapapọ Awọn Aimọ	≤1.0%
RD-3.1	≤0.10%
RD-C	≤0.10%
RD-D	≤0.10%
RD-E	≤0.10%
RP-Isomer	≤0.10%
Nitrophenol	≤0.10%
Awọn ohun elo ti o ku
Methanol Dichloride	≤6000ppm
Acetone	≤5000ppm
isopropyl Ọtí	≤5000ppm
Acetonitrile	≤410ppm
Dichloromethane	≤600ppm
Methyl tert Butyl Eteri	≤5000ppm
Ethyl acetate	≤5000ppm
Tetrahydrofuran	≤720ppm
n-Heptane	≤5000ppm
Ayẹwo	98.0% ~ 102.0% (Iṣiro lori ipilẹ ti o gbẹ)
Lapapọ Awọn iṣiro Aerobic
Awọn kokoro arun aerobic	≤100cfu/g
Iwukara ati Mold	≤10cfu/g
E. Okun	Odi
Endotoxin kokoro arun	≤1.0EU
Awọn irin Heavy	≤20ppm
Igbeyewo Standard	Standard Enterprise
Lilo	API, COVID-19

Package & Ibi ipamọ:

Package: Igo, apo apamọwọ Aluminiomu, ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.

Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.

Awọn anfani:

FAQ:

Ohun elo:

Remdesivir (CAS 1809249-37-3), ti a ta labẹ orukọ iyasọtọ Veklury, jẹ oogun ajẹsara ti o gbooro pupọ ti o dagbasoke nipasẹ ile-iṣẹ biopharmaceutical Gilead Sciences.O ti wa ni abojuto nipasẹ abẹrẹ sinu kan iṣọn.Lakoko ajakaye-arun COVID-19, remdesivir ti fọwọsi tabi fun ni aṣẹ fun lilo pajawiri lati tọju COVID-19 ni ayika awọn orilẹ-ede 50.Awọn itọnisọna imudojuiwọn lati Ajo Agbaye fun Ilera ni Oṣu kọkanla ọdun 2020 pẹlu iṣeduro ipo kan lodi si lilo Remdesivir fun itọju COVID-19.Remdesivir jẹ idagbasoke ni akọkọ lati tọju jedojedo C, ati pe o ṣe iwadii atẹle fun arun ọlọjẹ Ebola ati awọn akoran ọlọjẹ Marburg ṣaaju ki o to ṣe iwadi bi itọju ikọlu lẹhin fun COVID-19.Ipa ẹgbẹ ti o wọpọ julọ ni awọn oluyọọda ilera ni awọn ipele ẹjẹ ti o ga ti awọn enzymu ẹdọ (ami ti awọn iṣoro ẹdọ).Ipa ẹgbẹ ti o wọpọ julọ ni awọn eniyan ti o ni COVID-19 jẹ ríru.Awọn ipa ẹgbẹ le pẹlu iredodo ẹdọ ati iṣesi ti o ni ibatan idapo pẹlu ríru, titẹ ẹjẹ kekere, ati lagun.Remdesivir jẹ prodrug kan ti o pinnu lati gba ifijiṣẹ inu sẹẹli ti GS-441524 monophosphate ati biotransformation ti o tẹle sinu GS-441524 triphosphate, oludena analog ti ribonucleotide ti viral RNA polymerase.