Remdesivir Intermediate CAS 1354823-36-1 COVID-19 N-[(S)-(4-nitrophenoxy) phenoxyphosfinyl]-L-Alanine 2-ethylbutyl ester
Olupese Ipese Iṣowo Remdesivir ati Awọn agbedemeji ibatan pẹlu Didara Giga
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Orukọ Kemikali | N-[(S)-(4-nitrophenoxy) phenoxyphosfinyl]-L-Alanine 2-ethylbutyl ester |
Awọn itumọ ọrọ sisọ | Remdesivir Intermediate;Remdesivir Ẹgbẹ Ẹwọn;Remdesivir p-NitroPhenoxy L-Alanine Aimọ;Remdesivir Aimọ 4;Remdesivir-002;(S) -2-Ethylbutyl 2- (((S)- (4-nitrophenoxy) (phenoxy) -phosphoryl -amino) propanoate |
Nọmba CAS | 1354823-36-1 |
NỌMBA CAT | RF-PI297 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn ọgọọgọrun Kilogram |
Fọọmu Molecular | C21H27N2O7P |
Òṣuwọn Molikula | 450.42 |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Funfun to Fere White Powder |
Idanimọ | IR, HPLC |
Pipadanu lori Gbigbe | ≤1.0% |
Aimọ Kanṣoṣo | ≤0.50% |
Awọn irin Heavy | ≤20ppm |
Mimo | ≥98.0% |
Igbeyewo Standard | Standard Enterprise |
Lilo | Agbedemeji ti Remdesivir (CAS 1809249-37-3);COVID 19 |
Package: Igo, apo apamọwọ Aluminiomu, ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.
N-[(S)-(4-nitrophenoxy) phenoxyphosphinyl] -L-Alanine 2-ethylbutyl ester (CAS 1354823-36-1, tun mo bi Remdesivir Impurity 4) jẹ phosphoramidate sidechain ti a lo fun igbaradi ti Remdesivir (CAS) 1809249-37-3, GS-5734), eyiti o jẹ oogun iwadii ọlọjẹ aramada ni akọkọ fun itọju arun ọlọjẹ Ebola ati awọn akoran ọlọjẹ Marburg ati pe o tun rii lati ṣafihan iṣẹ ṣiṣe ọlọjẹ lodi si awọn coronaviruses (fun apẹẹrẹ SARS-Cov-2/ Covid 19).Lakoko ibesile ti Arun Coronavirus tuntun 2019 (COVID-19), Remdesivir (CAS 1809249-37-3) jẹ ọkan ninu awọn ọja iwadii ti o jọmọ COVID-19.Remdesivir, ti a ta labẹ orukọ iyasọtọ Veklury, jẹ oogun ajẹsara ti o gbooro pupọ ti o dagbasoke nipasẹ ile-iṣẹ biopharmaceutical Gilead Sciences.O ti wa ni abojuto nipasẹ abẹrẹ sinu kan iṣọn.Lakoko ajakaye-arun COVID-19, Remdesivir ti fọwọsi tabi fun ni aṣẹ fun lilo pajawiri lati tọju COVID-19 ni ayika awọn orilẹ-ede 50.Awọn itọnisọna imudojuiwọn lati Ajo Agbaye fun Ilera ni Oṣu kọkanla ọdun 2020 pẹlu iṣeduro ipo kan lodi si lilo Remdesivir fun itọju COVID-19.