Remdesivir Intermediate CAS 1911578-98-7 2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy) phosphoryl) -L-alaninate

Apejuwe kukuru:

Orukọ Kemikali: 2-Ethylbutyl ((S)-(perfluorophenoxy) (phenoxy) phosphoryl) -L-alaninate

CAS: 1911578-98-7

Irisi: Funfun si Paa-White PowderMimọ: ≥98.0%

Agbedemeji ti Remdesivir (CAS 1809249-37-3) COVID-19

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ọja Tags

Apejuwe:

Olupese Ipese Iṣowo Remdesivir ati Awọn agbedemeji ibatan pẹlu Didara Giga
Remdesivir CAS 1809249-37-3
2-Ethyl-1-butanol CAS 97-95-0
Trimethylsilyl Cyanide CAS 7677-24-9
4-Nitrophenol CAS 100-02-7
2-Ethylbutyl ((S)-(perfluorophenoxy) (phenoxy) phosphoryl) -L-alaninate CAS 1911578-98-7
N-[(S)-(4-nitrophenoxy) phenoxyphosfinyl] -L-Alanine 2-ethylbutyl ester CAS 1354823-36-1
(S)-2-Ethylbutyl 2-Aminopropanoate Hydrochloride CAS 946511-97-3
Remdesivir Metabolite (GS-441524) CAS 1191237-69-0
Remdesivir N-2 Agbedemeji CAS 1191237-80-5
2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5
7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine CAS 937046-98-5
Pyrrolo[1,2-F][1,2,4]Triazin-4-Amine CAS 159326-68-8
4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine CAS 1770840-43-1

Kemikali Properties:

Orukọ Kemikali	2-Ethylbutyl ((S)-(perfluorophenoxy) (phenoxy) phosphoryl) -L-alaninate
Awọn itumọ ọrọ sisọ	N-[(S) (2,3,4,5,6-pentafluorophenoxy) phenoxyphosphinyl] -L-Alanine 2-ethylbutyl ester;Remdesivir Intermediate;Remdesivir-001;Aimọ Remdesivir 21
Nọmba CAS	Ọdun 1911578-98-7
NỌMBA CAT	RF-PI303
Iṣura Ipo	Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn ọgọọgọrun Kilogram
Fọọmu Molecular	C21H27N2O7P
Òṣuwọn Molikula	495.38
iwuwo	1.2g/cm3
Ojuami Iyo	92.0 ~ 96.0 ℃ (tan.)
Ojuami farabale	356.7 ℃ ni 760 mmHg
Sowo Ipò	Sowo Labẹ Ibaramu otutu
Brand	Ruifu Kemikali

Awọn pato:

Nkan	Awọn pato
Ifarahan	Funfun to Pa-White Powder
Infurarẹẹdi julọ.Oniranran	Ni ibamu si Eto
Mimo	≥99.0%
Pipadanu lori Gbigbe	≤0.50%
Aimọ Kanṣoṣo	≤0.50%
Lapapọ Awọn Aimọ	≤1.0%
Awọn irin Heavy	≤20ppm
Igbeyewo Standard	Standard Enterprise
Lilo	Agbedemeji ti Remdesivir (CAS 1809249-37-3)

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Awọn anfani:

FAQ:

Ohun elo:

2-Ethylbutyl ((S)-(perfluorophenoxy) (phenoxy) phosphoryl) -L-alaninate (CAS 1911578-98-7) jẹ aarin bọtini to ti ni ilọsiwaju ni igbaradi ti awọn analogs ti o ni ibatan Remdesivir.Remdesivir jẹ oogun monophosphoramidate ti afọwọṣe adenosine, jẹ aṣoju ọlọjẹ gbooro-spekitiriumu iwadii pẹlu iṣẹ in vitro lodi si SARS coronavirus, MERS coronavirus ati, laipẹ diẹ, Covid-19.Remdesivir jẹ idagbasoke ni akọkọ bi itọju fun awọn akoran filovirus gẹgẹbi arun ọlọjẹ Ebola tabi ọlọjẹ Marburg.Lẹhinna, Remdesivir ni a rii lati ṣafihan iṣẹ ṣiṣe antiviral lodi si awọn ọlọjẹ RNA miiran ti o ni ẹyọkan gẹgẹbi ọlọjẹ syncytial atẹgun, ọlọjẹ Nipah, ọlọjẹ Hendra, ọlọjẹ Junin, ọlọjẹ iba Lassa ati awọn coronaviruses (pẹlu MERS ati awọn ọlọjẹ SARS).Laipẹ o jẹ ikẹkọ bi oogun ti o ni ileri fun itọju COVID-19 (ọlọjẹ iru SARS tuntun).Remdesivir, ti o dagbasoke nipasẹ Awọn sáyẹnsì Gileadi, jẹ oogun adenosine kan ti o ṣe iṣelọpọ sinu fọọmu ti nṣiṣe lọwọ GS-441524 eyiti o ṣe idiwọ iṣe ti RNA polymerase ti o gbẹkẹle RNA ati yago fun ṣiṣe atunṣe nipasẹ gbogun ti exoribonuclease (ExoN), nfa idinku ninu iṣelọpọ RNA gbogun.