Roflumilast CAS 162401-32-3 Assay 99.0~101.0% API

Apejuwe kukuru:

Orukọ Kemikali: Roflumilast

CAS: 162401-32-3

Ayẹwo: 99.0 ~ 101.0% (Ṣiṣiro lori ipilẹ ti o gbẹ)

Irisi: Funfun tabi Fere White Crystalline Powder

API PDE-4 inhibitor COPD

Olubasọrọ: Dokita Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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ọja Tags

Apejuwe:

Ipese Kemikali Ruifu Roflumilast Intermediates:
Roflumilast CAS 162401-32-3
4-Amino-3,5-Dichloropyridine CAS 22889-78-7

Kemikali Properties:

Orukọ Kemikali	Roflumilast
Awọn itumọ ọrọ sisọ	3- (Cyclopropylmethoxy) -N- (3,5-Dichloropyridin-4-yl)-4- (Ddifluoromethoxy) benzamide
Nọmba CAS	162401-32-3
NỌMBA CAT	RF-PI2075
Iṣura Ipo	Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu
Fọọmu Molecular	C17H14Cl2F2N2O3
Òṣuwọn Molikula	403.21
iwuwo	1.471 ± 0.060 g / cm3
Ifamọ	Ooru kókó
Brand	Ruifu Kemikali

Awọn pato:

Nkan	Awọn pato
Ifarahan	Funfun tabi Fere White Crystalline Powder
Solubility	Ọfẹ tiotuka ninu acetone, tiotuka diẹ ninu acetronitrile, aidiwọn diẹ ninu ethanol anhydrous, ni iṣe ti ko ṣee ṣe ninu omi
Ojuami Iyo	157.0 ~ 162.0 ℃
Pipadanu lori Gbigbe	<0.50%
Aloku lori Iginisonu	≤0.10%
Awọn irin Heavy	≤10ppm
Kloride	≤0.01%
Idanimọ A. UV	Awọn igbi ti o pọju gbigba yẹ ki o wa ni 213 ~ 251nm
Idanimọ B. IR	Apejuwe gbigba gbigba IR ni ibamu si ti itọkasi ọkan
Idanimọ C.	O ṣe afihan iṣesi ti fluoride
Awọn nkan ti o jọmọ
Aimọ Kanṣoṣo	≤0.10%
Lapapọ Awọn Aimọ	<0.50%
Awọn ohun elo ti o ku
Tert-Butanol	<0.10%
Tetrahydrofuran	<0.072%
Toluene	<0.089%
N, N-Dimethylformamide	<0.088%
Ayẹwo	99.0 ~ 101.0% (Iṣiro lori ipilẹ ti o gbẹ)
Igbeyewo Standard	Standard Enterprise
Lilo	API;COPD

Package & Ibi ipamọ:

Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara

Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin

Awọn anfani:

FAQ:

Ohun elo:

Roflumilast (CAS: 162401-32-3) jẹ oludena phosphodiesterase-4 (PDE-4) ti o yan ati akojọpọ benzamide.O jẹ idagbasoke nipasẹ ile-iṣẹ Jamani Altana ni ọdun 1993 ati pe o jẹ inhibitor PDE-4 ti ẹnu nikan ti a lo lati tọju awọn arun ti atẹgun ti a fọwọsi fun tita.Roflumilast jẹ oogun akọkọ ti iru rẹ lati dojukọ arun onibaje obstructive ẹdọforo (COPD), ati pe o tun jẹ oogun egboogi-iredodo akọkọ akọkọ ti o dagbasoke ni pataki fun awọn alaisan COPD.Awọn ohun-ini alailẹgbẹ rẹ le ṣe iranlọwọ lati ṣakoso COPD: nigba lilo ni apapo pẹlu bronchodilators lati tọju awọn alaisan COPD ti o nira pupọ, Roflumilast le ni anfani ti idinku awọn aami aisan siwaju ati iwọn ibajẹ, nitorinaa o jẹ ki o jẹ oogun akọkọ ti o fojusi awọn alaisan ti o ni ibajẹ loorekoore phenotype-spAecific COPD ati idena sisan afẹfẹ ti o lagbara ti o ni ibatan si iwúkọẹjẹ onibaje ati phlegm pupọ.Yato si jijẹ itọju fun COPD ti o lagbara, Roflumilast tun le ṣee lo lati ṣe idiwọ ati tọju awọn arun ti atẹgun atẹgun ti ẹran-ọsin, Ikọaláìdúró mucosa pupọ pupọ, anm ikọ-fèé, ati anm nla ati sacculitis afẹfẹ ti o tẹle pẹlu yomijade ti iṣan atẹgun ajeji.