(S) -1-Boc-3-Hydroxypiperidine CAS 143900-44-1 Ibrutinib Agbedemeji Mimọ>99.0% (GC)

Apejuwe kukuru:

Orukọ Kemikali: (S) -1-Boc-3-Hydroxypiperidine

CAS: 143900-44-1

Mimọ Chiral:>99.0% (GC)

Kẹmika Mimo:>99.0% (GC)

Irisi: Funfun Powder tabi kirisita

Agbedemeji ti Ibrutinib (CAS: 936563-96-1)

Didara to gaju, iṣelọpọ Iṣowo

E-Mail: alvin@ruifuchem.com


Alaye ọja

Jẹmọ Products

ọja Tags

Apejuwe:

Kemikali Properties:

Orukọ Kemikali (S) -1-Boc-3-Hydroxypiperidine
Awọn itumọ ọrọ sisọ (S) -1- (tert-Butoxycarbonyl) -3-Hydroxypiperidine;(S) -1-Boc-3-Piperidinol
Nọmba CAS 143900-44-1
NỌMBA CAT RF-CC299
Iṣura Ipo Ni Iṣura, Agbara iṣelọpọ 20 Tons / osù
Fọọmu Molecular C10H19NO3
Òṣuwọn Molikula 201.27
Ojuami Iyo 52.0 ~ 56.0 ℃
Solubility Tiotuka ni kẹmika
Yiyi pato [a] 20/D +9.0°~+11.0° (C=1 ninu Chloroform)
Brand Ruifu Kemikali

Awọn pato:

Nkan Awọn pato
Ifarahan Funfun Powder tabi kirisita
Chiral Mimọ > 99.5% (GC)
Kẹmika ti nw > 99.5% (GC)
Omi (KF) ≤0.50%
Methanol (GC) ≤50ppm
Ethanol (GC) ≤50ppm
DCM (GC) ≤500ppm
3-Hydroxypiperidine ≤0.10%
3-Hydroxypyridine ≤0.20%
1-Boc-3-Piperidone ≤0.10%
1-Boc-4-Hydroxypiperidine ≤0.10%
1,96 RRT ≤0.20%
Eyikeyi Aisọye Aimọ ≤0.10%
Igbeyewo Standard Standard Enterprise
Lilo Awọn agbedemeji elegbogi;Chiral Agbo

Package & Ibi ipamọ:

Package: Igo, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.

Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin.

Awọn anfani:

1

FAQ:

Ohun elo:

(S) -1-Boc-3-Hydroxypiperidine (CAS: 143900-44-1) jẹ agbedemeji chiral pataki fun iṣelọpọ ti Ibrutinib (CAS: 936563-96-1).Ibrutinib jẹ iru ti Bruton tyrosine kinase (BTK) onidalẹkun, o le ṣee lo fun awọn itọju ti onibaje lymphocytic aisan lukimia (CLL) ati mantle cell lymphoma (MCL).MCL ati CLL jẹ ti sẹẹli B-cell ti kii-Hodgkin's lymphoma, eyiti o nira lati ṣe iwosan ati rọrun lati loorekoore.Ajẹsara kemikali ti o wọpọ ko ni ibi-afẹde, nigbagbogbo waye 3 tabi 4 awọn aati ikolu.Ibrutinib ati B lymphocytes le ṣe ifọkansi pẹlu BTK eyiti o jẹ dandan fun dida, iyatọ, ati gbigbe alaye, ṣe idiwọ iṣẹ BTK ni aibikita, ati ṣe idiwọ itankale sẹẹli tumo ati iwalaaye daradara.Ibrutinib le gba ni kiakia lẹhin iṣakoso ẹnu, lakoko 1 ~ 2h de ọdọ ifọkansi ẹjẹ ti o pọju, awọn aati ikolu jẹ ti ọkan tabi meji, nitorinaa, Ibrutinib yoo di yiyan ti itọju CLL ati MCL tuntun.

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