(S)-3-Aminoquinuclidine Dihydrochloride CAS 119904-90-4 Purity ≥99.0% ee≥99.0% Palonosetron Hydrochloride Intermediate
Ipese Iṣowo Palonosetron Hydrochloride ati Awọn agbedemeji ibatan:
(S) -1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS: 85977-52-2
(R) -1,2,3,4-Tetrahedro-1-Naphthoic Acid CAS: 23357-47-3
(S)-3-Aminoquinuclidine Dihydrochloride CAS: 119904-90-4
3-Quinuclidinone Hydrochloride CAS: 1193-65-3
1-Naphthoic Acid CAS: 86-55-5
Palonosetron Hydrochloride CAS: 135729-62-3 API
| Orukọ Kemikali | (S) -3-Aminoquinuclidine Dihydrochloride |
| Awọn itumọ ọrọ sisọ | (S)-(-)-3-Aminoquinuclidine 2 HCL |
| Nọmba CAS | Ọdun 119904-90-4 |
| NỌMBA CAT | RF-CC112 |
| Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
| Fọọmu Molecular | C7H16Cl2N2 |
| Òṣuwọn Molikula | 199.12 |
| iwuwo | 1.24g/cm3 |
| Ojuami Iyo | 260℃ |
| Ojuami farabale | 470.4℃ ni 760mmHg |
| Solubility ninu Omi | Tiotuka |
| Sowo Ipò | Sowo Labẹ Ibaramu otutu |
| Brand | Ruifu Kemikali |
| Nkan | Awọn pato |
| Ifarahan | Funfun to Light Yellow Crystalline Powder |
| IR | Absorption Spectra Ni ibamu pẹlu Itọkasi |
| Idahun kiloraidi | Idahun rere |
| Mimọ (HPLC) | ≥98.0% |
| Pipadanu lori Gbigbe | ≤0.50% |
| Yiyi pato [α]D20 | -22.0°~ -26.0° (C=1, H2O) |
| Awọn irin Heavy | ≤20ppm |
| Ibi ipamọ | 5-8 ℃ Afẹfẹ |
| Igbeyewo Standard | Standard Enterprise |
| Lilo | Palonosetron Hydrochloride (CAS: 135729-62-3) Awọn agbedemeji |
(S)-3-Aminoquinuclidine Dihydrochloride (CAS: 119904-90-4) Ipa-ọna Sintetiki
Package: Igo, apo apamọwọ Aluminiomu, Ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.
Shanghai Ruifu Kemikali Co., Ltd jẹ olupilẹṣẹ asiwaju ati olupese ti (S) -3-Aminoquinuclidine Dihydrochloride (CAS: 2133-40-6) pẹlu didara to gaju.O jẹ agbedemeji elegbogi ni igbagbogbo ni iṣelọpọ ti Palonosetron Hydrochloride (CAS: 135729-62-3).
Palonosetron Hydrochloride (CAS: 135729-62-3) jẹ oogun kan lati dena ọgbun ati eebi, eyiti o jẹ iru tuntun ti o yan gaan, affinity 5-HT3 antagonist olugba giga ti o le dènà eebi reflex aarin awọn neurons agbeegbe presynaptic 5-HT.Idunnu olugba taara ni ipa lori eto aifọkanbalẹ aarin ni 5-HT.Idunnu olugba ti nfa ti ipilẹṣẹ nipasẹ ipa ti iṣan afferent vagal lẹhin agbegbe, didi awọn opin nafu ara vagus ninu ikun, idilọwọ awọn ifihan agbara si 5-HT.Agbegbe ti nfa olugba le dinku iṣẹlẹ ti ríru ati eebi.Aarin ile-iwosan fun itọju ti kimoterapi emetogenic nla ti o fa inu ríru idaduro ati eebi.Nitori ipa itọju giga rẹ, ipa ẹgbẹ kekere, igbesi aye idaji gigun (nipa awọn wakati 40), iwọn lilo kekere, ati bẹbẹ lọ, o ti fa ifojusi pupọ.Pẹlu 1,2,3,4-tetrahydro-1-naphthoic acid bi ohun elo ti o bẹrẹ, pipin, amination, idinku, cyclization, iyọ ti palonosetron hydrochloride granisetron.Awọn ijinlẹ ile-iwosan fihan pe palonosetron le ṣee lo lailewu pẹlu awọn corticosteroids, awọn analgesics, antiemetics, antispasmodics ati anticholinergic drugs bi awọn ohun elo ibẹrẹ, pipin, amination, idinku, cyclization, iyọ ti palonosetron hydrochloride granisetron.
