Sevelamer Carbonate CAS 845273-93-0 API Mimọ Giga Ile-iṣẹ
Ipese Olupese pẹlu Iwa-mimọ giga ati Didara Idurosinsin
Orukọ Kemikali: Sevelamer Carbonate
CAS: 845273-93-0
Sevelamer Carbonate jẹ amine polymeric ti o so fosifeti ati pe a lo lati ṣe itọju hyperphosphatemia ni awọn alaisan ti o ni arun kidinrin onibaje.
API Didara Giga, Iṣelọpọ Iṣowo
Orukọ Kemikali | Sevelamer Carbonate |
Awọn itumọ ọrọ sisọ | 2-Propen-1-Amine polima pẹlu (Chloromethyl) Oxirane Carbonate |
Nọmba CAS | 845273-93-0 |
NỌMBA CAT | RF-API28 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
Fọọmu Molecular | (C3H7N) m.(C3H5ClO) n.(CH2O3) x |
Òṣuwọn Molikula | 211.64 |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Funfun to Yellowish Powder |
Idanimọ A | Nipa IR, Lati baramu pẹlu boṣewa iṣẹ |
Idanimọ B | Yẹ ki o jẹ esi rere |
Kloride | ≤0.10% |
Pipadanu lori Gbigbe | ≤10.0% |
Aloku lori Iginisonu | ≤0.20% |
Awọn irin Heavy | ≤20ppm |
Igbeyewo Solubility | Yẹ ki o wa ni ibamu pẹlu bošewa |
Asopọmọra ti Phosphate | 3.0 ~ 7.0 mmol/g |
Oligomer ti o yanju | ≤0.20% |
Igbeyewo Standard | Standard Enterprise |
Ifarabalẹ | Daabobo lati ina ati Fipamọ ni aaye gbigbẹ tutu (≤5℃), Lilo to dara julọ laarin oṣu mẹfa |
Lilo | Ohun elo elegbogi ti nṣiṣe lọwọ (API) |
Package: Igo, apo apamọwọ Aluminiomu, ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.
Sevelamer carbonate jẹ amine polymeric ti o so fosifeti ati pe a lo lati ṣe itọju HYPERPHOSPHATEMIA ni awọn alaisan ti o ni arun kidinrin.Sevelamer carbonate jẹ resini paṣipaarọ anion, pẹlu ẹya polymeric kanna bi sevelamer hydrochloride, ninu eyiti kaboneti rọpo kiloraidi bi counterion.Lakoko ti awọn iṣiro yato fun awọn iyọ meji, polima funrarẹ, nkan ti nṣiṣe lọwọ ti o wa ninu abuda fosifeti, jẹ kanna.Sevelamer carbonate ni a mọ ni kemikali bi poly(allylamine-co-N, N'-diallyl-1,3diamino-2-hydroxypropane) iyọ carbonate.Sevelamer kaboneti jẹ hygroscopic, ṣugbọn insoluble ninu omi.Sevelamer Carbonate, polima ti ko ni gbigba jẹ adipọ fosifeti ti ẹnu ni awọn alaisan ti o ni ikuna kidinrin.O royin pe Sevelamer Carbonate ko ṣee ṣe lati fa hypercalcemia, awọn ipele kekere ti PTH, ati iṣọn-alọ ọkan ti o ni ilọsiwaju ati aortic calcification ninu awọn alaisan hemodialysis ju awọn binders fosifeti ti o da lori kalisiomu.