Sitagliptin Triazole Hydrochloride CAS 762240-92-6 Mimo>99.0% (HPLC) Didara Giga Factory
Ipese Sitagliptin Phosphate Monohydrate Awọn agbedemeji ibatan:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R) -3-Amino-4- (2,4,5-Trifluoro-Phenyl) -Butyric Acid CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Agbedemeji CAS 486460-21-3
Orukọ Kemikali | 3- (Trifluoromethyl) -5,6,7,8-tetrahydro-[1,2,4] triazolo [4,3-a] pyrazine Hydrochloride |
Awọn itumọ ọrọ sisọ | Sitagliptin Triazole Hydrochloride;Sitagliptin Agbedemeji A |
Nọmba CAS | 762240-92-6 |
NỌMBA CAT | RF-PI1193 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
Ilana molikula | C6H7F3N4·HCl |
Òṣuwọn Molikula | 228.60 |
Ojuami Iyo | 236.0 ~ 246.0 ℃ |
Solubility | Tiotuka ni kẹmika |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Funfun lati Pa-White Crystalline Powder |
Idanimọ nipa HPLC | Akoko idaduro ti ayẹwo jẹ ibamu pẹlu boṣewa itọkasi |
Idanimọ nipasẹ IR | Ibamu |
Pipadanu lori Gbigbe | <0.50% |
Awọn nkan ti o jọmọ | |
Eyikeyi Nikan Aimọ | <0.50% |
Lapapọ Awọn Aimọ | <1.00% |
Awọn Irin Eru | <20ppm |
Mimọ / Analysis Ọna | > 99.0% (HPLC) |
Igbeyewo Standard | Standard Enterprise |
Lilo | Agbedemeji Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9) |
Package: Igo, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin.
3-(Trifluoromethyl) -5,6,7,8-tetrahydro-[1,2,4]triazolo [4,3-a] pyrazine Hydrochloride (CAS: 762240-92-6) jẹ agbedemeji ti Sitagliptin Phosphate Monohydrate ( CAS: 654671-77-9), eyiti o jẹ inhibitor DPP4 yiyan ti ẹnu-bioavailable ti a ṣe awari nipasẹ iṣapeye ti kilasi kan ti awọn inhibitors DPP4 ti o ni β-aminoacid.O dinku iṣẹ ṣiṣe DPP4 ni ọna imuduro ni atẹle iṣakoso ojoojumọ lojoojumọ, ṣe itọju awọn ipele kaakiri ti GIP ti ko tọ ati GLP1 ni atẹle ounjẹ ni awọn ikẹkọ nla ati onibaje ati dinku awọn ipele glukosi ẹjẹ laisi awọn ilọsiwaju pataki ni hypoglycemia.Sitagliptin Phosphate (STG) ni a lo lati ṣe itọju DM iru 2 nitori pe o mu iṣakoso glycemic pọ si nipa jijẹ awọn ipele ti awọn homonu incretin ti nṣiṣe lọwọ, GLP-1 (peptide-1) ati GIP (glucose-based insulinotropic peptide).STG ti fọwọsi nipasẹ FDA ni ọdun 2006.