Sofosbuvir CAS 1190307-88-0 Mimọ ≥99.0% (HPLC)
Oruko | Sofosbuvir |
Awọn itumọ ọrọ sisọ | GS-7977;PSI-7977 |
Nọmba CAS | 1190307-88-0 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn ọgọọgọrun Kilogram |
Fọọmu Molecular | C22H29FN3O9P |
Òṣuwọn Molikula | 529.45 |
Ojuami Iyo | 120.0 ~ 125.0 ℃ |
iwuwo | 1.41 |
Solubility | Soluble ni DMF, DMSO, Ethanol |
Sowo Ipò | Labẹ Ibaramu otutu |
COA & MSDS | Wa |
Ipilẹṣẹ | Shanghai, China |
Igbesi aye selifu | Awọn oṣu 36 ti o ba fipamọ daradara |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Funfun lati Pa-White Crystalline Powder |
Idanimọ | HPLC;RT |
Mimọ / Analysis Ọna | ≥99.0% (HPLC) |
EE | ≥99.0% |
Pipadanu lori Gbigbe | ≤1.0% |
Aloku lori Iginisonu | ≤0.20% |
Aimọ Kanṣoṣo | ≤0.50% |
Lapapọ Awọn Aimọ | ≤1.0% |
Awọn irin Heavy | ≤20ppm |
Awọn ohun elo ti o ku | Pade awọn ibeere ti awọn pato |
kẹmika kẹmika | ≤1500ppm |
TBME | ≤2500ppm |
Dichloromethane | ≤720ppm |
Tetrahydrofuran | ≤720ppm |
Toluene | ≤60ppm |
Igbeyewo Standard | Standard Enterprise |
Lilo | Sofosbuvir (CAS: 1190307-88-0) ni itọju ti Ẹdọgba C Virus (HCV) |
Package: Igo, apo bankanje aluminiomu, 25kg / Ilu, tabi gẹgẹbi ibeere alabara
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin
Sofosbuvir (CAS: 1190307-88-0) (ti a fi aami si ni deede bi PSI-797, GS-7977) jẹ prodrug phosphoramidate ati inhibitor nucleotide polymerase fun itọju ti arun jedojedo C onibaje (HCV).A ṣe iṣeduro lati lo ni apapo pẹlu awọn oogun miiran (gẹgẹbi velpatasvir) fun itọju laini akọkọ fun HCV genotypes 1, 2, 3, 4, 5, ati 6. O gba ipa nipasẹ ṣiṣe bi oludena analog nucleotide, jije ti o lagbara lati ṣe idiwọ pataki HCV NS5B (amuaradagba ti kii ṣe igbekale 5B) RNA polymerase ti o gbẹkẹle.
Kọ ifiranṣẹ rẹ nibi ki o si fi si wa