Temozolomide (TMZ) CAS 85622-93-1 Assay 99.0%~101.0% API Factory High Purity
Ipese Temozolomide ati Awọn agbedemeji ti o jọmọ:
Temozolomide CAS: 85622-93-1
4 (5)-Amino-5 (4) -Imidazolecarboxamide CAS: 360-97-4
5 (4)-Amino-4 (5) -Imidazolecarboxamide Hydrochloride CAS: 72-40-2
| Orukọ Kemikali | Temozolomide |
| Awọn itumọ ọrọ sisọ | 3,4-Dihydro-3-Methyl-4-Oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-Carboxamide |
| Nọmba CAS | 85622-93-1 |
| NỌMBA CAT | RF-API29 |
| Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
| Fọọmu Molecular | C6H6N6O2 |
| Òṣuwọn Molikula | 194.15 |
| Ojuami Iyo | 212 ℃ Oṣu kejila. |
| Brand | Ruifu Kemikali |
| Nkan | Awọn pato |
| Ifarahan | Funfun to Light Pink lulú |
| Idanimọ | Nipasẹ IR, HPLC |
| Awọn ohun elo ti o ku | Dimethyl Sulphoxide ≤0.50% |
| Awọn nkan ti o jọmọ | |
| AIC aimọ | ≤0.10% |
| Aimọ Kanṣoṣo | ≤0.10% |
| Isinmi Aimọ Egbin | ≤0.30% |
| Lapapọ Awọn Aimọ | ≤0.30% |
| Awọn irin Heavy | ≤10ppm |
| Pipadanu lori Gbigbe | ≤0.50% |
| Aloku lori Iginisonu | ≤0.10% |
| Ayẹwo | 99.0% ~ 101.0% (HPLC lori ipilẹ gbigbẹ) |
| Igbeyewo Standard | Standard Enterprise |
| Lilo | Ohun elo elegbogi ti nṣiṣe lọwọ (API) |
Package: Igo, apo apamọwọ Aluminiomu, ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.
Shanghai Ruifu Chemical Co., Ltd jẹ olupilẹṣẹ asiwaju ati olupese ti Temozolomide (CAS: 85622-93-1) pẹlu didara to gaju.Temozolomide (TMZ) jẹ oluranlowo alkylating ẹnu ti a lo lati ṣe itọju Glioblastoma Multiforme (GBM) ati Astrocytomas, Metastatic Melanoma.
Temozolomide jẹ imunadoko akọkọ ti ẹnu ti a mu imidazole ati oogun anticancer kilasi tetrazine eyiti o jẹ ti iran keji ti oluranlowo alkylating pẹlu iṣẹ antitumor laisi imuṣiṣẹ iṣelọpọ ti ẹdọ lẹhin iṣakoso ẹnu.O jẹ ijuwe nipasẹ titẹ sii ni irọrun nipasẹ idena ọpọlọ-ẹjẹ, ifarada ti o dara ati pe ko ni fifẹ pẹlu majele ti awọn oogun miiran, ati nini ipa synergistic pẹlu radiotherapy eyiti o dara fun atọju isodipupo glioma buburu lẹhin itọju aṣa gẹgẹbi awọn èèmọ glioblastoma multiforme tabi astrocytoma degenerative.O jẹ oogun laini akọkọ fun itọju melanoma metastatic.
Temozolomide ti ni iṣakojọpọ akọkọ nipasẹ Ẹgbẹ Iwadi Cancer UK, ati lẹhinna gbe lọ si Ile-iṣẹ Schering-Plough (Amẹrika) fun idagbasoke.O ni eto kemikali aramada ati pe o jẹ ti itọsẹ mẹrin-imidazole.Ni ọdun 1999, o ti fọwọsi fun titẹ si ọja ni EU ati AMẸRIKA nibiti itọkasi idasilẹ ni Amẹrika jẹ pataki fun itọju ila-keji ti glioblastoma multiforme ati gliomas irawọ degenerative ati awọn itọkasi ti EU jẹ fun atọju idagbasoke tabi ifasẹyin glioblastoma multiforme. eyi ti o ti wa tẹlẹ koko ọrọ si mora ailera.Ipa ti temozolomide lori itọju glioblastoma multiforme ti gba idanimọ diẹ sii ni Yuroopu.
