Tolvaptan CAS 150683-30-0 API Mimọ> 99.0% (HPLC)
Tolvaptan Olupese Ipese ati Awọn agbedemeji ti o jọmọ:
Tolvaptan CAS 150683-30-0
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ọkan CAS 160129-45-3
ìwọ-Toluoyl kiloraidi CAS 933-88-0
4-Amino-2-Methylbenzoic Acid CAS 2486-75-1
2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5
| Oruko | Tolvaptan |
| Orukọ Kemikali | N-[4- (9-chloro-6-hydroxy-2-azabicyclo[5.4.0] undeca-8,10,12-triene-2-carbonyl)-3-methyl-phenyl]-2-methyl-benzamide |
| Nọmba CAS | 150683-30-0 |
| NỌMBA CAT | RF-API101 |
| Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
| Fọọmu Molecular | C26H25ClN2O3 |
| Òṣuwọn Molikula | 448.94 |
| Brand | Ruifu Kemikali |
| Nkan | Awọn pato |
| Ifarahan | Funfun lati Pa-White Crystalline Powder |
| Awọn ọna Idanimọ | IR, HPLC |
| Solubility | Soluble ni Benzyl Ọtí ati kẹmika ṣugbọn Ailokun Ni iṣe ninu Omi ati Hexane |
| Mimọ / Analysis Ọna | > 99.0% (HPLC) |
| Ojuami Iyo | 219.0 ~ 222.0 ℃ |
| Pipadanu lori Gbigbe | <0.50% |
| Aloku lori Iginisonu | <0.10% |
| Aimọ Kanṣoṣo | <0.50% |
| Lapapọ Awọn Aimọ | <1.00% |
| Awọn irin Heavy | ≤20ppm |
| Awọn ohun elo ti o ku | Pade Specification |
| Igbeyewo Standard | Standard Enterprise |
| Lilo | API;elegbogi Intermediates |
Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin
Tolvaptan (CAS: 150683-30-0), ti a tun mọ ni OPC-41061, jẹ yiyan, ifigagbaga arginine vasopressin receptor 2 antagonist ti a lo lati ṣe itọju hyponatremia (awọn ipele iṣuu iṣuu iṣuu ẹjẹ kekere) ti o ni nkan ṣe pẹlu ikuna ọkan iṣọn-ẹjẹ, cirrhosis, ati aarun ti homonu antidiuretic ti ko yẹ (SIADH).Otsuka Pharmaceutical tolvaptan ni iwe-aṣẹ labẹ orukọ iṣowo Samsca lẹhin ti FDA fọwọsi oogun naa ni Oṣu Karun ọdun 2009. Tolvaptan tun ti ṣe afihan ipa lodi si arun kidirin polycystic.Ninu idanwo ọdun 2004, tolvaptan ti a nṣakoso pẹlu awọn diuretics ibile ni a ṣe akiyesi lati mu iyọkuro ti awọn fifa pupọ pọ si ati mu awọn ipele iṣuu soda ẹjẹ pọ si ni awọn alaisan ti o ni ikuna ọkan laisi iṣelọpọ awọn ipa ẹgbẹ bii hypotension (titẹ ẹjẹ kekere) tabi hypokalemia (idinku awọn ipele ẹjẹ ti potasiomu).Oogun naa tun ṣe afihan ko si ipa buburu lori iṣẹ kidirin.
![7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ọkan CAS 160129-45-3 Tolvaptan Intermediate](https://www.ruifuchemical.com/uploads/7-Chloro-1234-tetrahydrobenzobazepin-5-one-CAS-160129-45-3-300x300.jpg)
