Valsartan CAS 137862-53-4 Assay 98.0~102.0% API
Olupese Ipese Valsartan ati Awọn agbedemeji ti o jọmọ:
Valsartan CAS: 137862-53-4
L-Valine Methyl Ester Hydrochloride (H-Val-OMe·HCl) CAS: 6306-52-1
Orukọ Kemikali | Valsartan |
Awọn itumọ ọrọ sisọ | N-Valeryl-N-[2'- (1H-tetrazol-5-yl) biphenyl-4-ylmethyl]-L-valine |
Nọmba CAS | 137862-53-4 |
NỌMBA CAT | RF-API32 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
Fọọmu Molecular | C24H29N5O3 |
Òṣuwọn Molikula | 435.52 |
Ojuami Iyo | 116.0 ~ 117.0 ℃ |
Iduroṣinṣin | Hygroscopic |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Funfun tabi Paa-funfun lulú;Odorless, Hygroscopic |
Idanimọ | IR julọ.Oniranran ti awọn ayẹwo ibaamu awọn itọkasi bošewa julọ.Oniranran |
Idanimọ | Akoko idaduro ti tente oke pataki ni chromatogram ti igbaradi ayẹwo ni ibamu si ti igbaradi boṣewa, bi a ti gba ni Assay. |
Solubility | Soluble ni Methanol ati Ethanol, Pupọ Tiotuka ni Ethylacetate, Tiotuka diẹ ninu Dichloromethane, Ailesolusan ninu Omi |
Ọrinrin (KF) | ≤1.00% |
Gbigbe (420mm) | ≤0.02% (λ=420nm, C=0.05g/ml, L=1cm) |
Aloku lori Iginisonu | ≤0.10% |
Awọn irin Heavy | ≤10ppm |
D-Valsartan | ≤1.00% (HPLC) |
Awọn nkan ti o jọmọ (HPLC) | |
Butyryl-Valsartan | ≤0.20% |
Benzyl-Valsartan | ≤0.10% |
Nikan Unknown Inpurity | ≤0.10% |
Lapapọ Awọn Aimọ | ≤0.30% (Laisi D-Valsartan) |
Awọn ojutu ti o ku (GC) | |
kẹmika kẹmika | ≤3000ppm |
Ethyl acetate | ≤5000ppm |
N, N-Dimethylformamide | ≤880ppm |
Toluene | ≤890ppm |
Mimọ / Analysis Ọna | > 99.0% (iṣiro HPLC lori ipilẹ anhydrous, ipilẹ ti ko ni epo) |
Igbeyewo Standard | Orilẹ Amẹrika Pharmacopoeia (USP) |
Lilo | Ohun elo elegbogi ti nṣiṣe lọwọ (API) |
Valsartan (CAS: 137862-53-4) Sisan ilana iṣelọpọ
Package: Igo, apo bankanje aluminiomu, 25kg / Paali ilu, tabi gẹgẹ bi ibeere alabara
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina ati ọrinrin
Shanghai Ruifu Chemical Co., Ltd jẹ olupilẹṣẹ asiwaju ati olupese ti Valsartan (CAS: 137862-53-4) pẹlu didara to gaju.Valsartan jẹ angiotensin II AT1 olugba olugba ti kii ṣe peptide, Antihypertensive, ni agbara fun titẹ ẹjẹ giga ati iwadii ikuna ọkan.
Awọn ipa antihypertensive Valsartan lagbara ju ti enalapril lọ ati pe o dara fun itọju haipatensonu, ìwọnba si iwọn haipatensonu akọkọ, ati paapaa haipatensonu keji ti o fa nipasẹ ibajẹ kidirin.O le dinku proteinuria ni pataki fun awọn alaisan haipatensonu pẹlu àtọgbẹ tabi awọn iṣẹ ẹdọ deede, ati pe o le ṣe agbega uric acid ati iṣuu soda ito lati daabobo kidinrin.Valsartan tun dara fun idinku iku iku inu ọkan ati ẹjẹ fun awọn alaisan ti o ni eewu giga (ikuna ventricular osi tabi ailagbara) lẹhin iriri ikọlu ọkan.