Vidarabine (Ara-A) CAS 5536-17-4 Purity≥99.0% (HPLC) Didara Giga Factory
Olupese Ipese Arabinonucleosides Intermediates pẹlu Giga Mimo
Vidarabine;Ara-A;CAS: 5536-17-4
Arabinofuranosyluracil;Ara-U ;CAS: 3083-77-0
Cytarabine;Ara-C;CAS: 147-94-4
Orukọ Kemikali | Vidarabine |
Awọn itumọ ọrọ sisọ | Ara-A;Arabinoadenosine;Adenine 9-β-D-Arabinofuranoside;Vira-A |
Nọmba CAS | 5536-17-4 |
NỌMBA CAT | RF-PI220 |
Iṣura Ipo | Ninu Iṣura, Iwọn iṣelọpọ Ti o to Awọn Toonu |
Ilana molikula | C10H13N5O4 |
Òṣuwọn Molikula | 267.25 |
Brand | Ruifu Kemikali |
Nkan | Awọn pato |
Ifarahan | Funfun tabi Pa-White Crystalline Powder |
Solubility | Alailowaya Kedere |
Mimọ / Analysis Ọna | ≥99.0% (HPLC) |
UV akoonu | ≥98% (lori ipilẹ gbigbẹ) |
Yiyi pato [a] D20 | -56.0°~-65.0° (C=1 ninu DMF) |
Adenine | ≤0.50% |
Adenosine | ≤0.50% |
Ara-U | ≤0.50% |
Ojuami Iyo | 260.0 ~ 265.0 ℃ |
Awọn Irin Eru | ≤20ppm |
Igbeyewo Standard | Standard Enterprise |
Ibi ipamọ otutu | Tọju ni 0 ~ 8 ℃ |
Lilo | API;elegbogi Intermediates |
Package: Igo, apo apamọwọ Aluminiomu, ilu paali, 25kg / Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ sinu awọn apoti ti a fi edidi ni itura ati ibi gbigbẹ;Dabobo lati ina, ọrinrin ati kokoro infestation.
Vidarabine (CAS: 5536-17-4), jẹ oogun apakokoro ti o nṣiṣẹ lọwọ lodi si awọn ọlọjẹ herpes simplex ati varicella zoster.Vidarabine (CAS: 5536-17-4) jẹ neurotransmitter ti o ṣe bi agonist endogenous ti o fẹ ni gbogbo awọn subtypes olugba adenosine.Vidarabine (CAS: 5536-17-4) jẹ inhibitor A cyclase ati DNA Polymerase.Adenine 9-beta-D-arabinofuranoside (ara-A) jẹ purine nucleoside ti iṣelọpọ ti iṣelọpọ ti a lo ninu iwadii ifihan sẹẹli.O ti lo ni igbagbogbo ni iwadii egboogi-gbogun ti pẹlu hepadnaviridae ati awọn ọlọjẹ herpes simplex.Awọn nucleoside ara-A dabaru pẹlu gbogun ti DNA kolaginni, sugbon nikan ni awọn oniwe-ṣiṣẹ phosphorylated fọọmu.
Vidarabine (CAS: 5536-17-4) jẹ apakokoro nucleoside ti o ya sọtọ lati Streptomyces antibioticus.O ni diẹ ninu awọn ohun-ini antineoplastic ati pe o ni iṣẹ iwoye gbooro si awọn ọlọjẹ DNA ni awọn aṣa sẹẹli ati iṣẹ ṣiṣe antiviral pataki si awọn akoran ti o fa nipasẹ ọpọlọpọ awọn ọlọjẹ bii awọn ọlọjẹ Herpes, VACCINIA VIRUS ati ọlọjẹ varicella zoster.Vidarabine (CAS: 5536-17-4) ni o lagbara lati dena acyclovir-sooro/TK-deficient mutanti ti HSV ati VZV, nitori ti o ti wa ni phosphorylated si awọn oniwe-fidarabine-triphosphate fọọmu ti nṣiṣe lọwọ nipasẹ cellular kinases ati ki o jẹ ko ti o gbẹkẹle fun awọn oniwe-iṣiṣẹ lori awọn gbogun ti TK.