1-(1-Benzothiophen-4-yl)piperazine Hydrochloride CAS 913614-18-3 Purity >98.0% (HPLC) Brexpiprazole Intermediate Factory
I-Ruifu Chemical Supply Brexpiprazole Intermediates
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4-Bromobenzo[b]thiophene CAS 5118-13-8
1-(1-Benzothiophen-4-yl)piperazine Hydrochloride CAS 913614-18-3
7-(4-Chlorobutoxy)quinolin-2(1H)-one CAS 913613-82-8
4-Chlorobenzo[b]thiophene CAS 66490-33-3
Igama Lekhemikhali | 1-(1-Benzothiophen-4-yl)piperazine Hydrochloride |
Omqondofana | I-Brexpiprazole Ephakathi 2;I-1-Benzo[b]thien-4-yl-Piperazine Hydrochloride;I-1-Benzo[b]thien-4-ylpiperazine Monohydrochloride |
Inombolo ye-CAS | 913614-18-3 |
Inombolo yeCAT | I-RF-PI1034 |
Isimo Sesitoko | Esitokweni, Amandla Okukhiqiza 100MT/Ngonyaka |
I-Molecular Formula | I-C12H15ClN2S |
Isisindo samangqamuzana | 254.7789 |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | Impushana Emhlophe Kuya Kumhlophe |
Ukuhlonza | Isikhathi sokugcinwa kwesampula sihambisana naleso sezinga lesithenjwa |
Ukuhlanzeka / Indlela Yokuhlaziya | >99.0% (HPLC) |
Ukulahlekelwa Ekumisweni | <0.50% |
Amanzi (KF) | <0.50% |
Izinsalela Ekushiseni | <0.20% |
Izinto Ezihlobene | (HPLC) |
Noma yikuphi Ukungcola Komuntu Ngamunye | <0.50% |
Ukungcola Okuphelele | <1.00% |
I-Infrared Spectrum | Ivumelana Nesakhiwo |
I-Proton NMR Spectrum | Ivumelana Nesakhiwo |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | I-Intermediate ye-Brexpiprazole (CAS: 913611-97-9) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama
I-1-(1-Benzothiophen-4-yl)piperazine Hydrochloride (CAS: 913614-18-3) iphakathi kwe-Brexpiprazole (CAS: 913611-97-9).I-Brexpiprazole iwuhlobo lwe-atypical antipsychotic.Kuyi-dopamine D2 receptor partial agonist.Njengenoveli ye-serotonin-dopamine modulator yomsebenzi, ingasetshenziselwa ukwelapha i-schizophrenia, kanye nokwelashwa okuhlanganisayo kokudangala.Ingase futhi inikeze ukusebenza kahle kanye nokubekezelelana phezu kokwelashwa okuhlanganisiwe okusungulwe i-formajor depressive disorder(MDD).Isidakamizwa sibonisa iphrofayili ye-pharmacological eyingqayizivele, esebenza njenge-agonist ingxenye ye-serotonin 5-HT1A kanye ne-dopamine D2 receptors futhi njengomphikisi ogcwele we-5-HT2A kanye ne-noradrenaline α1B / 2C receptors, enobudlelwane obubophezelayo obufanayo be-subnanomolar.Umuthi, owakhiwa u-Otsuka kanye no-Lundbeck, wagunyazwa ngo-2015 yi-FDA ukuze welaphe i-schizophrenia kanye nokwelapha okuhlanganisa nokudangala.