1-(2,3-Dichlorophenyl)piperazine Hydrochloride CAS 119532-26-2 Aripiprazole Intermediate Purity >99.0% (HPLC)
Abahlinzeki Bempahla Abaphakathi Be-Aripiprazole Ngokuhlanzeka Okuphezulu
I-Aripiprazole API CAS 129722-12-9
1-(2,3-Dichlorophenyl)piperazine Hydrochloride CAS 119532-26-2
I-7-Hydroxy-3,4-Dihydro-2(1H)-Quinolinone CAS 22246-18-0
7-(4-Bromobutoxy)-3,4-Dihydro-2(1H)-Quinolinone CAS 129722-34-5
Igama Lekhemikhali | I-1-(2,3-Dichlorophenyl) i-piperazine Hydrochloride |
Omqondofana | 2,3-DCPP HCl;1-(2,3-Dichlorophenyl) piperazine HCl;I-Aripiprazole EP Ukungcola B;I-Aripiprazole Inhlanganisela Ehlobene C |
Inombolo ye-CAS | 119532-26-2 |
Inombolo yeCAT | I-RF-PI2268 |
Isimo Sesitoko | Esitokweni, Amandla Okukhiqiza 30 MT/Inyanga |
I-Molecular Formula | C10H12Cl2N2·HCl |
Isisindo samangqamuzana | 267.58 |
I-Melting Point | 245.0~247.0℃ |
Isitoreji Nokuzwela | I-Hygroscopic.Amazinga okushisa e-ambient |
Ukuncibilika Emanzini | Incibilika Emanzini |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | Impushana Emhlophe noma Engamhlophe |
Ukuhlanzeka / Indlela Yokuhlaziya | >99.0% (HPLC) |
Ukulahlekelwa Ekumisweni | <0.50% |
Izinsalela ekushiseni | <0.10% |
Ukungcola Okukodwa | <0.50% |
Ukungcola Okuphelele | <1.00% |
Izinsimbi Ezisindayo (njenge-Pb) | ≤20ppm |
I-Infrared Spectrum | Ivumelana Nesakhiwo |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | I-Intermediate ye-Aripiprazole (CAS: 129722-12-9) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende
Isimo Sesitoreji:I-Hygroscopic.Gcina kude namanzi/umswakama kanye nama-oxidizing agents.Gcina isitsha sivalwe ngokuqinile bese usibeka endaweni epholile, eyomile futhi engenawo umoya.Gcina ngaphansi kwegesi engasebenzi
I-1-(2,3-Dichlorophenyl) i-piperazine Hydrochloride (i-CAS: 119532-26-2) iyingxenye ebalulekile ye-Aripiprazole (CAS: 129722-12-9).I-Aripiprazole iwuhlobo olusha lokuphuma kokuphuma kwe-quinoline e-lipid encibilika kakhulu, isici sayo sezemithi ukuthi akuyona nje i-postsynaptic dopamine D 2 receptor antagonist, kodwa futhi i-presynaptic dopamine D 2 receptor agonist, ingaphinde ijabulise u-D 1, D 3, D 4 ama-receptors;inomphumela okabili wokwenza kusebenze ingxenye noma ukuphikisa kwesamukeli ku-5-HT 1A isamukeli;inesenzo esiphikisana ngokuphelele nesamukeli se-5-HT 2A.Lesi sici sihlukile kunesesizukulwane sokuqala, kanye nama-antipsychotic atypical ayingxenye yezidakamizwa ze-antipsychotic zesizukulwane sesibili, ngakho-ke sibizwa ngokuthi i-dopamine system stabilizer noma i-antipsychotic yesizukulwane sesithathu.Njengoba ithengiswa emakethe, isetshenziswa kakhulu ku-schizophrenia yomtholampilo, ekwelapheni ukuphazamiseka okuthintayo nezinye izifo zengqondo.Ngokusho kwezincwadi, i-aripiprazole inemiphumela ebalulekile ku-schizophrenia izimpawu ezinhle nezimbi nokukhathazeka, ukucindezeleka, umsebenzi wokuqonda, kuyilapho ukuphepha okuphezulu.Kuphinde kwabikwa ukuthi lesi sidakamizwa singakwazi futhi ukwelapha ezinye izifo zengqondo, njenge-mood disorders manic episodes, i-senile dementia ehambisana nokuphazamiseka kwengqondo, ukuphazamiseka kokukhathazeka, ukuphazamiseka kokuziphatha kwezingane, ukucindezeleka.Namuhla, iBristol-Myers Squibb kanye ne-Otsuka Pharmaceutical Company bamemezele ukuthi i-European Union igunyaze i-Abilify (aripiprazole) ekwelapheni isicelo sokufakwa kuhlu kwe-schizophrenia.