1-[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine CAS 340041-91-0 Purity>98.0% (HPLC) I-Almotriptan Malate Intermediate Factory

Incazelo emfushane:

Igama: 1-[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine

I-CAS: 340041-91-0

Ubumsulwa: >98.0% (HPLC)

I-Intermediate ye-Almotriptan Malate (CAS: 181183-52-8)

Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo

E-Mail: alvin@ruifuchem.com


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Chemical Properties:

Igama Lekhemikhali 1 - [(4-Nitrophenylmethyl)sulfonyl]pyrrolidine
Omqondofana N- [(4-Nitrophenyl)-methylsulfonyl]pyryolidine;1-((4-Nitrobenzyl)sulfonyl)pyrrolidine
Inombolo ye-CAS 340041-91-0
Inombolo yeCAT I-RF-PI1959
Isimo Sesitoko Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula I-C11H14N2O4S
Isisindo samangqamuzana 270.30
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into Imininingwane
Ukuhlanzeka / Indlela Yokuhlaziya >98.0% (HPLC)
Ukulahlekelwa Ekumisweni <1.00%
Izinga Lokuhlola I-Enterprise Standard
Ukusetshenziswa I-Intermediate ye-Almotriptan Malate (CAS: 181183-52-8)

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama

Izinzuzo:

1

I-FAQ:

Isicelo:

I-1--[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine (CAS: 340041-91-0) iphakathi Ukulungiselela i-Almotriptan Malate (CAS: 181183-52-8).I-Almotriptan Malate iyi-agonist ye-serotonin (5-HT) ye-receptor subtypes 5-HT1Bkanye ne-5-HT1D(IC50s=12 kanye no-13 nM, ngokulandelana, ku-assay ebophezelayo ye-radioligand).I-Almotriptan Malate (LAS 31416) i-5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist ekhethiwe, esetshenziselwa ukwelapha ukuhlaselwa kweMigraine kubantu abadala.I-Almotriptan, imakethwa ngo-2000, ine-oralbioavailability ephezulu kakhulu phakathi kwawo wonke ama-triptan.I-Metabolized by kokubili i-MAO-A ne-CYP3A4, ngaleyo ndlela inephrofayili yemiphumela emihle kakhulu uma iqhathaniswa ne-Sumatriptan.

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