1-[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine CAS 340041-91-0 Purity>98.0% (HPLC) I-Almotriptan Malate Intermediate Factory
I-Ruifu Chemical Supply Almotriptan Malate Intermediates:
I-Almotriptan Malate CAS 181183-52-8
I-1-((4-Hydrazinylbenzyl)sulfonyl)pyrrolidine Hydrochloride CAS 334981-11-2
4-[(1-Pyrrolidinylsulfonyl)methyl]aniline CAS 334981-10-1
1-[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine CAS 340041-91-0
I-4-Chlorobutyraldehyde Diethyl Acetal CAS 6139-83-9
Igama Lekhemikhali | 1 - [(4-Nitrophenylmethyl)sulfonyl]pyrrolidine |
Omqondofana | N- [(4-Nitrophenyl)-methylsulfonyl]pyryolidine;1-((4-Nitrobenzyl)sulfonyl)pyrrolidine |
Inombolo ye-CAS | 340041-91-0 |
Inombolo yeCAT | I-RF-PI1959 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C11H14N2O4S |
Isisindo samangqamuzana | 270.30 |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukuhlanzeka / Indlela Yokuhlaziya | >98.0% (HPLC) |
Ukulahlekelwa Ekumisweni | <1.00% |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | I-Intermediate ye-Almotriptan Malate (CAS: 181183-52-8) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama
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I-1--[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine (CAS: 340041-91-0) iphakathi Ukulungiselela i-Almotriptan Malate (CAS: 181183-52-8).I-Almotriptan Malate iyi-agonist ye-serotonin (5-HT) ye-receptor subtypes 5-HT1Bkanye ne-5-HT1D(IC50s=12 kanye no-13 nM, ngokulandelana, ku-assay ebophezelayo ye-radioligand).I-Almotriptan Malate (LAS 31416) i-5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist ekhethiwe, esetshenziselwa ukwelapha ukuhlaselwa kweMigraine kubantu abadala.I-Almotriptan, imakethwa ngo-2000, ine-oralbioavailability ephezulu kakhulu phakathi kwawo wonke ama-triptan.I-Metabolized by kokubili i-MAO-A ne-CYP3A4, ngaleyo ndlela inephrofayili yemiphumela emihle kakhulu uma iqhathaniswa ne-Sumatriptan.