I-1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS 143254-82-4 Irinotecan Hydrochloride Intermediate High Purity
Umkhiqizi Uhlinzeka Nge-Irinotecan kanye Nezixhumanisi Ezihlobene:
I-Irinotecan Hydrochloride CAS: 100286-90-6
I-Irinotecan Free Base CAS: 97682-44-5
I-Irinotecan Hydrochloride Trihydrate CAS: 136572-09-3
I-7-Ethyl-10-Hydroxycamptothecin CAS: 86639-52-3
I-1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS: 143254-82-4
| Igama Lekhemikhali | I-1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride |
| Inombolo ye-CAS | 143254-82-4 |
| Inombolo yeCAT | I-RF-PI243 |
| Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
| I-Molecular Formula | I-C11H20Cl2N2O |
| Isisindo samangqamuzana | 267.2 |
| Ibhrendi | I-Ruifu Chemical |
| Into | Imininingwane |
| Ukubukeka | Impushana Emhlophe noma Ephuzi Ekhanyayo |
| Isivivinyo | ≥98.0% (HPLC) |
| Ukulahlekelwa Ekumisweni | ≤1.0% |
| Izinsimbi Ezisindayo | ≤20ppm |
| Izinga Lokuhlola | I-Enterprise Standard |
| Ukusetshenziswa | Okumaphakathi kwe-Irinotecan Hydrochloride (CAS: 100286-90-6) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi oholayo kanye nomphakeli we-1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride (CAS: 143254-82-4) enekhwalithi ephezulu.Kuyinto emaphakathi ngokuvamile ekuhlanganisweni kwe-Irinotecan Hydrochloride (CAS: 100286-90-6), i-DNA Topoisomerase I Inhibitor.
I-lrinotecan hydrochloride, i-semi-synthetic, ephuma emanzini encibilikayo ye-ejenti enamandla yokulwa nomdlavuza i-camptothecin, yethulwa e-Japan ukuze zelashwe umdlavuza wamaphaphu, we-ovary, nowomlomo wesibeletho.I-lrinotecan yenza umsebenzi wayo we-antitumor ngokuvimbela i-topoisomerase I, i-enzyme yeselula ehilelekile ekugcineni ukwakheka kwendawo ye-DNA phakathi nenqubo yokuhumusha, ukuloba, kanye ne-mitosis.I-lrinotecan yenza i-de-esterification ku-vivo ukuze ikhiqize i-metabolite esebenzayo, i-SN-38, enamandla ngokuphindwe ka-1000 kunomzali.Nakuba inobuthi obuncane kakhulu kune-camptothecin, inani elibalulekile leziguli ezivivinyweni zomtholampilo labonisa imiphumela emibi ye-leukopenia, isifo sohudo, isicanucanu, kanye ne-alopecia.
