1,3,5-Tri-O-benzoyl-D-Ribofuranose CAS 22224-41-5 Ubumsulwa ≥99.0% Clofarabine Intermediate High Purity

Incazelo emfushane:

Igama Lekhemikhali: 1,3,5-Tri-O-benzoyl-D-Ribofuranose

I-CAS: 22224-41-5

Ukubukeka: Impushana Emhlophe noma Engamhlophe

Ubumsulwa: ≥99.0%

I-Intermediate of Clofarabine (CAS: 123318-82-1) ekwelapheni Izingane ezine-Acute Lymphoblastic Leukemia (BONKE)

Inquiry: alvin@ruifuchem.com


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

I-Commercial Supply Okuhlobene Okuhlobene:
I-Clofarabine CAS: 123318-82-1
2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-α-D-arabinofuranose CAS: 97614-43-2
I-β-D-Ribofuranose 1-Acetate 2,3,5-Tribenzoate CAS: 6974-32-9
1,3,5-Tri-O-benzoyl-D-Ribofuranose CAS: 22224-41-5
I-2,6-Dichloropurine CAS: 5451-40-1

Chemical Properties:

Igama Lekhemikhali 1,3,5-Tri-O-benzoyl-D-Ribofuranose
Inombolo ye-CAS 22224-41-5
Inombolo yeCAT I-RF-PI223
Isimo Sesitoko Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula I-C26H22O8
Isisindo samangqamuzana 462.45
I-Melting Point 125.0-129.0℃(lit.)
Ukuncibilika Ayincibiliki Emanzini
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into Imininingwane
Ukubukeka Impushana Emhlophe noma Engamhlophe
Ubumsulwa ≥99.0%
Ukulahlekelwa Ekumisweni ≤1.00%
Ukungcola Okukodwa Okukhulu ≤0.50%
Ukungcola Okuphelele ≤1.00%
Izinsimbi Ezisindayo ≤20ppm
Izinga Lokuhlola I-Enterprise Standard
Ukusetshenziswa I-Intermediate ye-Clofarabine (CAS: 123318-82-1)

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.

Izinzuzo:

1

I-FAQ:

12

Isicelo:

I-1,3,5-Tri-O-benzoyl-D-Ribofuranose (i-CAS: 22224-41-5) iyinto yokuqala ye-nucleoside synthesis.Ingasetshenziswa njengendawo ephakathi yeClofarabine (CAS: 123318-82-1).I-Clofarabine iyinoveli yemithi elwa nomdlavuza we-purine nucleoside eqala ukuthuthukiswa ngempumelelo yi-Top10 biopharmaceutical company ye-United States-Genzyme Corporation amagama okuhweba athi “Clofarabine”.Ngomhla zingama-28 kuZibandlela wezi-2004 i-FDA yasebenzisa i-fast-track ukuze igunyaze i-Clofarabine ukuze isetshenziswe ezinganeni ezine-refractory noma i-relapsed acute lymphocytic leukemia.I-Clofarabine ihlanganisa izinzuzo ze-Fludarabine ne-Cladribine ukuvimbela kokubili i-DNA polymerase ne-RIbonucleic acid reductase.Njengamanje ukuphela kwesidakamizwa esifanele ukwelashwa kwe-leukemia yezingane.Ucwaningo luye lwafakazela ukuthi ukusebenza kahle kwayo kokwelapha kuphezulu kakhulu, futhi izinga lokuphendula eliphelele leziguli ezingenayo impendulo kumakhemikhali amabili avamile angama-31%.Futhi ukubekezelelana ngesineke kuhle, akukho ukusabela okubi okungalindelekile;Inezici ezingase zibe ne-broad-spectrum antitumor.

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