(1S,2R)-(-)-1-Amino-2-indanol CAS 126456-43-7 Purity ≥99.0% EE ≥99.0% Indinavir Sulfate Intermediate
Umkhiqizi onekhwalithi ephezulu kanye nenani elincintisanayo
I-Commercial Supply Indinavir Sulfate (CAS: 157810-81-6) Izimaphakathi Ezihlobene:
(1R,2S)-(+)-1-Amino-2-indanol CAS: 136030-00-7
(1S,2R)-(-)-1-Amino-2-indanol CAS: 126456-43-7
| Igama Lekhemikhali | (1S,2R)-(-)-1-Amino-2-indanol |
| Omqondofana | (1S,2R)-(-)-1-Amino-2-hydroxyundan |
| Inombolo ye-CAS | 126456-43-7 |
| Inombolo yeCAT | I-RF-CC120 |
| Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
| I-Molecular Formula | C9H11NO |
| Isisindo samangqamuzana | 149.19 |
| I-Solubility (I-Soluble in) | I-Methanol |
| Ibhrendi | I-Ruifu Chemical |
| Into | Imininingwane |
| Ukubukeka | Impushana Emhlophe Kuya Kuphaphathekile Ephuzi |
| Ukuzungezisa Okuqondile [α]D20 | -47.0°~ -42.0° (C=1,MeOH) |
| I-Melting Point | 115.0~121.0℃ |
| Ukuhlanzeka / Indlela Yokuhlaziya | ≥99.0% (HPLC) |
| Ukulahlekelwa Ekumisweni | ≤0.50% |
| Umswakama (KF) | ≤0.50% |
| EE | ≥99.0% |
| Izinga Lokuhlola | I-Enterprise Standard |
| Ukusetshenziswa | I-Indinavir Sulfate (CAS: 157810-81-6) Abaphakathi |
Iphakheji: Ibhodlela, I-Cardboard Drum, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi oholayo nomphakeli we-(1S,2R)-(-)-1-Amino-2-indanol (CAS: 126456-43-7) enekhwalithi ephezulu.(1S,2R)-(-)-1-Amino-2-indanol (CAS: 126456-43-7) iyindawo emaphakathi ngokuvamile ekuhlanganisweni kwe-Indinavir Sulfate (CAS: 157810-81-6).
I-Indinavir Sulfate (i-CAS: 157810-81-6) (MK-639) iyi-protease inhibitor esetshenziswa njengengxenye yokwelashwa kwe-antiretroviral esebenzayo kakhulu (HAART) ukwelapha ukutheleleka nge-HIV kanye ne-AIDS.I-MK-639 ibonakala inomsebenzi obalulekile we-antiviral ohlobene nomthamo futhi ubekezelelwa kahle.I-Indinavir iyi-inhibitor enamandla ye-HIV reverse transcriptase.Ikhiqiza imiphumela emibi evamile kuwo wonke ama-protease inhibitors futhi ingase ikhiqize i-nephrolithiasis, urolithiasis, kanye nokungasebenzi kahle kwezinso noma ukwehluleka kwezinso.Le nkinga yenzeke kaningi ezinganeni (cishe u-30%) kunabantu abadala (cishe u-10%) futhi ingancishiswa ngokuphuza okungenani u-1.5 L wamanzi nsuku zonke.Imiphumela engemihle eyengeziwe ihlanganisa i-asymptomatic hyperbilirubinemia, i-alopecia, izinzipho ezingene ngaphakathi, kanye ne-paronychia.I-anemia ye-Hemolytic ayivamile ukwenzeka.I-Rifampin akufanele inikezwe ne-indinavir.
