(1S,2S,3R,5S)-(+)-2,3-Pinanediol CAS 18680-27-8 ee ≥99.0% Purity ≥99.0% Bortezomib Intermediate High Purity
Nikeza Abaphakathi Abahlobene Ne-Bortezomib Ngokuhlanzeka Okuphezulu
(1S,2S,3R,5S)-(+)-2,3-Pinanediol CAS 18680-27-8
(1R,2R,3S,5R)-(-)-2,3-Pinanediol CAS 22422-34-0
I-Bortezomib CAS 179324-69-7
Igama Lekhemikhali | (1S,2S,3R,5S)-(+)-2,3-Pinanediol |
Omqondofana | (1S,2S,3R,5S)-2,6,6-Trimethylbicyclo[3.1.1]heptane-2,3-diol |
Inombolo ye-CAS | 18680-27-8 |
Inombolo yeCAT | I-RF-CC290 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C10H18O2 |
Isisindo samangqamuzana | 170.25 |
Ukuncibilika | I-Chloroform, iToluene |
Isimo Sokuthumela | Kuthunyelwe Ngaphansi Kwezinga Lokushisa Le-Ambient |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | I-Crystallized Powder Emhlophe ukuya Kokumhlophe |
I-Melting Point | 56.0 ~ 59.0℃ |
Ukulahlekelwa Ekumisweni | ≤0.50% |
Izinsalela ekushiseni | ≤0.50% |
I-Enantiomeric Excess | ee≥99.0% |
Ukuhlanzeka / Indlela Yokuhlaziya | ≥99.0% (GC) |
Ukuzungezisa Okuthile [α]20/D | +8.5° ukuya +9.5° (C=6.5, Toluene) |
I-Infrared Spectrum | Kuyavumelana |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | I-Chiral Compounds;Abalamuli Bezemithi;I-Bortezomib Intermediate |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, I-Cardboard Drum, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
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I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi oholayo kanye nabaphakeli be-(1S,2S,3R,5S)-(+)-2,3-Pinanediol (CAS 18680-27-8) enekhwalithi ephezulu, esetshenziswa kabanzi ku-organic. synthesis, synthesis of pharmaceutical intermediate and fine chemical synthesis.
I-Shanghai Ruifu Chemical Co., Ltd. idlala indima ebalulekile kumakhemikhali e-chiral, inkampani izibophezele ekukhiqizeni ama-chiral compounds.Imikhiqizo yethu inconywa kakhulu ngamakhasimende.
(1S,2S,3R,5S)-(+)-2,3-Pinanediol (CAS 18680-27-8), iyi-reagent ye-Chiral ewusizo esetshenziselwa ukuhlanganiswa kwe-homochiral α-hydroxyketones kanye nokuxazululwa kwe-prolineboronate esters.Kuphinde kube isandulela esiwusizo se-chiral allyl boronate esetshenziswa ekulungiseleleni i-chiral β-hydroxyallylsilanes.
(1S,2S,3R,5S)-(+)-2,3-Pinanediol (CAS 18680-27-8) i-Intermediate of Bortezomib (CAS 179324-69-7) ekwelapheni kwe-Multiple Myeloma.I-Bortezomib, i-ubiquitin proteasome (26S) inhibitor enamandla (Ki=0.6 nM), yethulwa e-US njengokwelashwa kwe-myeloma eminingi.Le proteasome iyadingeka ekonakalisweni kwe-proteolytic yamaprotheni amaningi eselula futhi ikhona kuwo wonke amaseli.Iyadingeka ukuze kulawulwe izinqubo zokuvuvukala, ukulawulwa komjikelezo wamaseli kanye nokubonakaliswa kofuzo futhi iyinoveli okuhloswe ngayo ekwelashweni komdlavuza.