I-2-Chloroadenine CAS 1839-18-5 Assay ≥98.0% (HPLC) Factory
Ukunikezwa Komkhiqizi, Ukuhlanzeka Okuphezulu, Ukukhiqizwa Kwezohwebo
Igama Lekhemikhali: 2-Chloradenine
CAS: 1839-18-5
Igama Lekhemikhali | 2-Chloroadenine |
Omqondofana | I-6-Amino-2-Chloropurine;Cladribine EP Ukungcola B |
Inombolo ye-CAS | 1839-18-5 |
Inombolo yeCAT | I-RF-PI513 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C5H4ClN5 |
Isisindo samangqamuzana | 169.57 |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | Impushana Ephuzi ukuya Emhlophe |
Indlela Yokuhlola / Yokuhlaziya | ≥98.0% (HPLC) |
I-Melting Point | ≥300℃ |
Ukulahlekelwa Ekumisweni | ≤0.50% |
Izinsalela ekushiseni | ≤0.50% |
Izinsimbi Ezisindayo (njenge-Pb) | ≤0.001% |
Ukungcola Okuphelele | ≤2.0% |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | Ophakathi kweClofarabine (CAS: 123318-82-1), uCladribine (CAS: 4291-63-8) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama.
I-2-Chloradenine (i-CAS: 1839-18-5) isetshenziswa ngokuyinhloko njenge-intermediate ye-Clofarabine (CAS: 123318-82-1), i-Cladribine (i-CAS: 4291-63-8) namanye ama-API.I-Clofarabine iyinoveli yemithi elwa nomdlavuza ye-purine nucleoside eqala ukuthuthukiswa ngempumelelo yinkampani ye-biopharmaceutical Top10 ye-United States-Genzyme Corporation.Ngomhla zingama-28 kuZibandlela wezi-2004 i-US Food and Drug Administration (FDA) yasebenzisa ithrekhi esheshayo ukuze kugunyazwe i-clofarabine ukuze isetshenziswe ezinganeni ezine-refractory noma i-acute lymphocytic leukemia ebuyele emuva.I-Cladribine (2-chloro-2′-deoxyadenosine) iyi-analogue emelana ne-adenosine deaminase ye-deoxyadenosine.Umuthi unohlu olubanzi lomsebenzi we-in vitro ngokumelene ne-lymphoid ne-myeloid neoplasms.