I-2-(Chloromethyl)-4-Methylquinazoline CAS 109113-72-6 I-Linagliptin Ubumsulwa obumaphakathi ≥99.0% (HPLC)

Incazelo emfushane:

Igama Lekhemikhali: 2-(Chloromethyl) -4-Methylquinazoline

I-CAS: 109113-72-6

Ubumsulwa: ≥99.0% (HPLC)

Ukubukeka: Okuphuzi Okuphaphathekile kuya Kuphuphu Olunsundu Ophaphathekile

I-Linagliptin emaphakathi (CAS: 668270-12-0) yokwelashwa kwabantu abadala abanesifo sikashukela sohlobo 2.

Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo

E-Mail: alvin@ruifuchem.com


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Chemical Properties:

Igama Lekhemikhali 2-(Chloromethyl)-4-Methylquinazoline
Omqondofana I-Linagliptin Intermediate A
Inombolo ye-CAS 109113-72-6
Inombolo yeCAT I-RF-PI498
Isimo Sesitoko Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula I-C10H9ClN2
Isisindo samangqamuzana 192.64
Ukuminyana 1.251
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into Imininingwane
Ukubukeka Impushana Ephuzi Okuphaphathekile kuya Kuphuphu Olunsundu
Ukuhlonza A Isampula ye-IR spectrum kufanele ihambisane ne-spectrum evamile
Ukuhlonza B Isikhathi sokugcinwa sokuphakama kwesimiso sesampula kufanele sihambisane nokujwayelekile
Ukuncibilika I-Soluble ku-Methylene Chloride;Ayincibiliki Emanzini
Ukuhlanzeka / Indlela Yokuhlaziya ≥99.0% (HPLC)
I-Melting Point 60.0 ukuze 65.0℃
Amanzi (KF) ≤0.50%
Izinsalela ekushiseni ≤0.50%
Izinto Ezihlobene  
Ukungcola Okukodwa ≤0.30%
Ukungcola Okuphelele ≤1.0%
Izinga Lokuhlola I-Enterprise Standard
Ukusetshenziswa Okumaphakathi kwe-Linagliptin (CAS: 668270-12-0)

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama.

Izinzuzo:

1

I-FAQ:

Isicelo:

I-2-(Chloromethyl)-4-Methylquinazoline (i-CAS: 109113-72-6) isetshenziswa njengendawo emaphakathi yokulungiswa kwe-Linagliptin (CAS: 668270-12-0), kanye nokungcola kwayo.I-Linagliptin, ethengiswa ngaphansi kwegama lomkhiqizo i-Tradjenta phakathi kokunye, umuthi osetshenziselwa ukwelapha isifo sikashukela sohlobo 2. Imvamisa ayithandwa kakhulu kune-metformin ne-sulfonylureas njengokwelashwa kokuqala.Isetshenziswa kanye nokuzivocavoca kanye nokudla.Akunconyelwe uhlobo 1 sikashukela.Isebenza ngokwandisa ukukhiqizwa kwe-insulin nokunciphisa ukukhiqizwa kwe-glucagon ngamanyikwe.I-Linagliptin yagunyazwa ukusetshenziswa kwezokwelapha e-United States ngo-2011. I-Linagliptin inamandla kakhulu, ikhetha i-dipeptidyl peptidase-4 (DPP-4) inhibitor ene-IC50 ye-1 nM.

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