I-2-(Chloromethyl)-4-Methylquinazoline CAS 109113-72-6 I-Linagliptin Ubumsulwa obumaphakathi ≥99.0% (HPLC)
I-Linagliptin Yomkhiqizi kanye Nezixhumanisi Ezihlobene:
I-Linagliptin CAS 668270-12-0
I-Linagliptin Parent Nucleus Intermediate CAS 853029-57-9
8-Bromo-3-Methylxanthine CAS 93703-24-3
8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine CAS 666816-98-4
I-2-(Chloromethyl)-4-Methylquinazoline CAS 109113-72-6
(R)-3-(Boc-Amino)piperidine CAS 309956-78-3
(R)-(-)-3-Aminopiperidine Dihydrochloride CAS 334618-23-4
1-Bromo-2-Butyne CAS 3355-28-0
Igama Lekhemikhali | 2-(Chloromethyl)-4-Methylquinazoline |
Omqondofana | I-Linagliptin Intermediate A |
Inombolo ye-CAS | 109113-72-6 |
Inombolo yeCAT | I-RF-PI498 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C10H9ClN2 |
Isisindo samangqamuzana | 192.64 |
Ukuminyana | 1.251 |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | Impushana Ephuzi Okuphaphathekile kuya Kuphuphu Olunsundu |
Ukuhlonza A | Isampula ye-IR spectrum kufanele ihambisane ne-spectrum evamile |
Ukuhlonza B | Isikhathi sokugcinwa sokuphakama kwesimiso sesampula kufanele sihambisane nokujwayelekile |
Ukuncibilika | I-Soluble ku-Methylene Chloride;Ayincibiliki Emanzini |
Ukuhlanzeka / Indlela Yokuhlaziya | ≥99.0% (HPLC) |
I-Melting Point | 60.0 ukuze 65.0℃ |
Amanzi (KF) | ≤0.50% |
Izinsalela ekushiseni | ≤0.50% |
Izinto Ezihlobene | |
Ukungcola Okukodwa | ≤0.30% |
Ukungcola Okuphelele | ≤1.0% |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | Okumaphakathi kwe-Linagliptin (CAS: 668270-12-0) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama.
I-2-(Chloromethyl)-4-Methylquinazoline (i-CAS: 109113-72-6) isetshenziswa njengendawo emaphakathi yokulungiswa kwe-Linagliptin (CAS: 668270-12-0), kanye nokungcola kwayo.I-Linagliptin, ethengiswa ngaphansi kwegama lomkhiqizo i-Tradjenta phakathi kokunye, umuthi osetshenziselwa ukwelapha isifo sikashukela sohlobo 2. Imvamisa ayithandwa kakhulu kune-metformin ne-sulfonylureas njengokwelashwa kokuqala.Isetshenziswa kanye nokuzivocavoca kanye nokudla.Akunconyelwe uhlobo 1 sikashukela.Isebenza ngokwandisa ukukhiqizwa kwe-insulin nokunciphisa ukukhiqizwa kwe-glucagon ngamanyikwe.I-Linagliptin yagunyazwa ukusetshenziswa kwezokwelapha e-United States ngo-2011. I-Linagliptin inamandla kakhulu, ikhetha i-dipeptidyl peptidase-4 (DPP-4) inhibitor ene-IC50 ye-1 nM.