I-2-Hydroxy-5-Methylpyridine CAS 1003-68-5 Ubumsulwa ≥99.0% I-Pirfenidone Intermediate Factory
Ukunikezwa Komkhiqizi, Ukuhlanzeka Okuphezulu, Ukukhiqizwa Kwezohwebo
Igama Lekhemikhali: 2-Hydroxy-5-Methylpyridine
I-CAS: 1003-68-5
| Igama Lekhemikhali | I-2-Hydroxy-5-Methylpyridine |
| Omqondofana | I-5-Methyl-2(1H)-Pyridinone;I-2-Hydroxy-5-Picoline;I-6-Hydroxy-3-Picoline;I-5-Methyl-2-Pyridinol |
| Inombolo ye-CAS | 1003-68-5 |
| Inombolo yeCAT | I-RF-PI549 |
| Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
| I-Molecular Formula | C6H7NO |
| Isisindo samangqamuzana | 109.13 |
| I-Melting Point | 183.0 kuye ku-187.0 ℃ (lit.) |
| Ukuncibilika | I-Soluble ku-Methanol |
| Ibhrendi | I-Ruifu Chemical |
| Into | Imininingwane |
| Ukubukeka | I-Off-White to Yellow Crystalline Powder |
| Ubumsulwa | ≥99.0% |
| Okuqukethwe Komswakama (KF) | ≤0.50% |
| Izinsalela ekushiseni | ≤0.50% |
| Noma Ikuphi Ukungcola Okukodwa | ≤0.50% |
| Ukungcola Okuphelele | ≤1.00% |
| Izincibilikisi Ezisele | |
| n-Butanol | ≤0.30% |
| I-Ethanol | ≤0.30% |
| Izinga Lokuhlola | I-Enterprise Standard |
| Ukusetshenziswa | I-Pirfenidone emaphakathi (CAS: 53179-13-8) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama
I-2-Hydroxy-5-Methylpyridine (i-CAS: 1003-68-5) isetshenziswa njengendawo ephakathi yemithi ye-Pirfenidone (CAS: 53179-13-8).I-Pirfenidone (PFD) iwuhlobo lwenoveli lwama-pyridine ketone anomphumela obanzi we-anti-fibrotic, okwazi ukuvimbela nokubuyisela emuva ukwakheka kwe-fibrosis nesibazi.Yangena emakethe e-Shionogi, e-Japan ngo-2008 futhi yagunyazwa yi-US Food and Drug Administration.Uwumuthi wokuqala odlule ezivivinyweni zomtholampilo zesigaba sesi-III (okuhlanganisa ukuphindaphinda, okungahleliwe, nokulawulwa kwe-placebo) obonise ukusebenza kahle kwawo ekwelapheni i-idiopathic pulmonary fibrosis (IPF);ngaphezu kwalokho, isidakamizwa sisebenza kahle kakhulu ekwelapheni ezinye izifo ze-fibrotic ezifana ne-renal interstitial fibrosis kanye ne-fibrosis yesibindi.
