I-2,3-Dihydrobenzofuran CAS 496-16-2 Ramelteon Intermediate Purity >99.0% (GC)

Incazelo emfushane:

Igama Lekhemikhali: 2,3-Dihydrobenzofuran

Synonym: Coumaran;2,3-Dihydrobenzo[b]furan

CAS: 496-16-2

Ubumsulwa: >99.0% (GC)

Ukubukeka: Sula Uketshezi Olungenambala noma Oluphuzi

I-Intermediate of Ramelteon (CAS: 196597-26-9)

Thintana: UDkt. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Umkhiqizi Oholayo Nomhlinzeki, Abaphakathi kwe-Ramelteon
I-Ramelteon (TAK-375) CAS 196597-26-9
2,3-Dihydrobenzofuran CAS 496-16-2
1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-one CAS 196597-78-1
I-Ramelteon Acrylonitrile CAS 196597-79-2
I-Despropionyl Ramelteon Hydrochloride CAS 196597-80-5
2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethanamine Hydrochloride CAS 1053239-39-6
Please contact: alvin@ruifuchem.com

Chemical Properties:

Igama Lekhemikhali	2,3-Dihydrobenzofuran
Omqondofana	Coumaran;2,3-Dihydro-2,3-Benzofuran;2,3-Dihydrobenzo[b]furan;2,3-Dihydro-1-Benzofuran
Inombolo ye-CAS	496-16-2
Inombolo yeCAT	I-RF2884
Isimo Sesitoko	Esitokweni, Amandla Okukhiqiza Amathani angama-20 ngenyanga
I-Molecular Formula	C8H8O
Isisindo samangqamuzana	120.15
I-Melting Point	-21℃
Iphuzu elibilayo	188.0~189.0℃ (okhanyisiwe)
I-Flash Point	66℃
Ukuncibilika	Utshwala: Buyancibilika
Inothi Lengozi	Iyacasula
I-TSCA	Yebo
Ikhodi ye-HS	29329995
Isikhathi Sokugcina.	Kuvalwe kokuthi Omile, Izinga lokushisa Legumbi
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Into	Imininingwane
Ukubukeka	Sula Uketshezi Olungenambala noma Oluphuzi
Ukuhlanzeka / Indlela Yokuhlaziya	>99.0% (GC)
Amanzi (nguKarl Fischer)	<0.50%
Ukuminyana (20℃)	1.065~1.085
I-Refractive Index n20/D	1.547~1.551
Ukungcola Okukodwa	<0.50%
Ukungcola Okuphelele	<1.00%
I-Proton NMR Spectrum	Ivumelana Nesakhiwo
Izinga Lokuhlola	I-Enterprise Standard
Ukusetshenziswa	I-Pharmaceutical Intermediate ye-Ramelteon (CAS: 196597-26-9)

Iphakheji nesitoreji:

Iphakheji: Ibhodlela Elifakwe Fluorinated, 25kg/Drum, noma ngokwezidingo zekhasimende

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama

Izinzuzo:

Amandla Anele: Izinsiza ezanele kanye nochwepheshe

Isevisi Yobuchwepheshe: Isevisi yokuthenga yokuma eyodwa

Iphakheji le-OEM: Iphakheji yangokwezifiso kanye nelebula iyatholakala

Ukulethwa Okusheshayo: Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe

Impahla Ezinzile: Gcina isitoko esinengqondo

Ukusekelwa Kwezobuchwepheshe: Isixazululo sezobuchwepheshe siyatholakala

Isevisi Yokuhlanganisa Ngokwezifiso: Isukela kumagremu kuye kumakhilo

Ikhwalithi Ephezulu: Kusungulwe uhlelo oluphelele lokuqinisekisa ikhwalithi

I-FAQ:

Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

Iminyaka engu-15 Yokuhlangenwe nakho?Sinesipiliyoni seminyaka engaphezu kwe-15 ekwakhiweni nasekuthumeleni kwamanye amazwe uhla olubanzi lwezinga eliphezulu lokuxhumanisa imithi noma amakhemikhali amahle.

Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eKorea, eJapane, e-Australia, njll.

Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.

IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.

Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.

Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.

I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.

Isikhathi sokuthumela? Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe.

Ezokuthutha?By Express (FedEx, DHL), by Air, by Sea.

Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.

Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.

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Isicelo:

I-2,3-Dihydrobenzofuran (i-CAS: 496-16-2) isetshenziswa kabanzi ekuhlanganiseni ama-tricyclic compounds futhi ibuye ibe yimpahla eluhlaza ephakathi ukuze kuhlanganiswe ezinye izidakamizwa ezibalulekile.I-2,3-Dihydrobenzofuran ingasetshenziswa njengendawo ephakathi ye-Ramelteon (i-CAS: 196597-26-9).I-Ramelteon, imakethwa njenge-Rozerem yi-Takeda Pharmaceuticals North America, iyi-ejenti yokulala ebopha ngokukhetha kuma-receptors e-MT1 kanye ne-MT2 ku-nucleus ye-suprachiasmatic (SCN), esikhundleni sokubophezela kuma-receptors e-GABAA, njengezidakamizwa ezifana ne-zolpidem.Nokho akubonakali kusheshisa ukuqala kokulala noma inani lokulala umuntu alala ngalo.Kugunyazwe i-US Food and Drug Administration (FDA) ukuze isetshenziswe isikhathi eside.I-Ramelteon ayibonisi noma yikuphi ukubopha okuncomekayo kuma-GABAA receptors, ahlotshaniswa ne-anxiolytic, myorelaxant, nemiphumela ye-amnesic.Ngokungafani nokwelashwa okuningi kokuqwasha okuqondise ku-GABA (g-aminobutyric acid) receptor complex, i-ramelteon iyi-agonist ye-melatonin receptor.Ikakhulukazi, inokukhetha okuphezulu kwe-MT1 ne-MT2 subtypes, eye yathinteka ekugcinweni kwezigqi ze-circadian, ngaphezu kwesamukeli se-MT3 esibhekele eminye imisebenzi ye-melatonin.I-2,3-Dihydrobenzofuran nayo isetshenziselwa ukuhlanganiswa kwama-antitumor agents i-benzofuran sulfonylureas, i-HIV protease inhibitor amino acid hydroxyethylenesulfonyl, i-matrix metalloproteinase inhibitor aryl sulfinyl isoxime hydroxamic acid, njll.