2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5 Remdesivir Intermediate COVID-19

Incazelo emfushane:

Igama: 2,3,5-Tri-O-benzyl-D-ribonolactone

Synonimes: 2,3,5-Tri-O-Benzyl-D-Ribono-1,4-Lactone

I-CAS: 55094-52-5

Ukubukeka: Impushana Emhlophe Ukuya Kucishe Emhlophe

Ubumsulwa: ≥99.0%

I-Intermediate ye-Remdesivir (CAS 1809249-37-3) COVID-19

Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo

Inquiry: alvin@ruifuchem.com

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Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Umkhiqizi Wokuhlinzeka Ngempahla Yezohwebo i-Remdesivir kanye Nezixhumanisi Ezihlobene Nekhwalithi Ephezulu
I-Remdesivir CAS 1809249-37-3
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2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate CAS 1911578-98-7
N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester CAS 1354823-36-1
(S)-2-Ethylbutyl 2-Aminopropanoate Hydrochloride CAS 946511-97-3
I-Remdesivir Metabolite (GS-441524) CAS 1191237-69-0
I-Remdesivir N-2 I-CAS Emaphakathi 1191237-80-5
2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5
7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine CAS 937046-98-5
I-Pyrrolo[1,2-F][1,2,4]Triazin-4-Amine CAS 159326-68-8
4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine CAS 1770840-43-1

Chemical Properties:

Igama Lekhemikhali	2,3,5-Tri-O-benzyl-D-ribonolactone
Omqondofana	2,3,5-Tri-O-Benzyl-D-Ribono-1,4-Lactone;I-Remdesivir Intermediate
Inombolo ye-CAS	55094-52-5
Inombolo yeCAT	I-RF-PI301
Isimo Sesitoko	Esitokweni, Isikali Sokukhiqiza Sifika Emakhulwini Amakhilogremu
I-Molecular Formula	I-C26H26O5
Isisindo samangqamuzana	418.49
I-Melting Point	54.0-55.0℃
Isimo Sesitoreji	Ukushisa Kwegumbi
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Into	Imininingwane
Ukubukeka	Okuqinile Okuphuzi noma Okumhlophe
Ukuncibilika	Incibilika ku-CH2Cl2 futhi Ayincibiliki ku-H2O
I-NMR ne-MS	Kufanele Uhambisane
Ukuhlonza	I-IR ne-TLC
Umswakama	≤1.0%
Izinsalela ekushiseni	≤0.50%
Noma yikuphi Ukungcola Komuntu Ngamunye	≤0.50%
Izinsimbi Ezisindayo	≤50ppm
I-HPLC (210nm)	≥99.0%
I-HPLC (ELSD)	≥99.0%
Izinga Lokuhlola	I-Enterprise Standard
Ukusetshenziswa	I-Intermediate ye-Remdesivir (CAS 1809249-37-3)

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.

Izinzuzo:

I-FAQ:

Isicelo:

I-2,3,5-Tri-O-benzyl-D-ribonolactone (CAS 55094-52-5) iyi-Remdesivir emaphakathi.I-Remdesivir (CAS 1809249-37-3) iyinoveli yomuthi we-antiviral ekilasini lama-nucleotide analog, esetshenziswa ekwelapheni i-COVID-19.I-Remdesivir (GS-5734) iyinoveli ye-nucleoside analogue ye-antiviral evimbela i-murine hepatitis virus (MHV) ene-EC50 efanayo ne-SARS-CoV ne-MERS-CoV.Ama-Coronaviruses (CoVs) angamagciwane e-RNA anomucu owodwa athinta inqwaba yezilwane.Kubantu, ama-CoV aqashelwa njengokujwayelekile abangela imikhuhlane kanye nenyumoniya kwaze kwaba yilapho kuvela i-acute acute respiratory syndrome (SARS-CoV) ngo-2002 kanye ne-Middle East Respiratory Syndrome coronavirus (MERS-CoV) ngo-2012 emithonjeni ye-zoonotic.I-Remdesivir iyi-monophosphoramidate prodrug ye-C-adenosine nucleoside analogue GS-441524.Kumaseli e-brain tumor (DBT) abambezelekile atheleleke nge-MHV, i-GS-5734 ivimbe i-MHV ngamandla kune-GS-441524, nge-GS-5734 EC50 ka-0.03 M. Ngaphezu kwalokho, amanani e-EC50 anqunywa ngemva kokwelashwa nge-GS-441524 kanye ne-GS-5734 ne-GS-5734 emasikweni e-SARS-CoV- kanye ne-MERS-CoV-infected primary human airway epithelial cell (HAE).