2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0 Purity ≥99.5% (GC) Sitagliptin Phosphate Monohydrate Intermediate
Thola Izimo Ezihlobene Ne-Sitagliptin Phosphate Monohydrate:
I-Sitagliptin API CAS 486460-32-6
I-Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
I-Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
I-Sitagliptin Triazole Hydrochloride CAS 762240-92-6
I-Sitagliptin Phosphate Monohydrate Intermediate CAS 486460-21-3
Igama Lekhemikhali | 2,4,5-Trifluorophenylacetic Acid |
Inombolo ye-CAS | 209995-38-0 |
Inombolo yeCAT | I-RF-PI1191 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C8H5F3O2 |
Isisindo samangqamuzana | 190.12 |
I-Melting Point | 121.0 ukuze 125.0 ℃ |
Ukuncibilika | I-Soluble ku-Methanol |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | Impushana Emhlophe Kuya Kumhlophe |
Ukuhlanzeka / Indlela Yokuhlaziya | ≥99.5% (GC) |
Umswakama (KF) | ≤0.50% |
Izinsalela ku-Igniton | ≤0.50% |
Ukungcola Okuphelele | ≤0.50% |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | Okumaphakathi kwe-Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama.
I-2,4,5-Trifluorophenylacetic Acid (CAS: 209995-38-0) iphakathi kwe-Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9).I-Sitagliptin Phosphate (STG) isetshenziselwa ukwelapha uhlobo 2 lwe-DM ngoba ithuthukisa ukulawulwa kwe-glycemic ngokwandisa amazinga ama-incretin hormone asebenzayo, i-GLP-1 (peptide-1) ne-GIP (i-insulinotropic peptide encike kuglucose).Ukwenziwa kusebenze kwalawa ma-incretin kumaseli e-β-pancreatic kubangela ukwanda kwamazinga e-cyclic adenosine monophosphate (cAMP) kanye ne-intracellular calcium, kanye nokuphuma kwe-insulin encike ku-glucose (2).Lo muthi we-hypoglycemic ungowesigaba esisha esibizwa ngokuthi i-dipeptidyl peptidase IV inhibitors.I-STG yavunywa yi-FDA ngo-2006.