(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8 Atazanavir Intermediate High Purity
Impahla Ehlobene Nomkhiqizi i-Atazanavir
I-Moc-L-Tert-Leucine CAS 162537-11-3
4-(2-Pyridyl)benzaldehyde CAS 127406-56-8
(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2
(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8
tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate CAS 198904-85-7
I-Atazanavir CAS 198904-31-3
I-Atazanavir Sulfate CAS 229975-97-7
Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo
Igama Lekhemikhali | (2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane |
Omqondofana | (2R,3S)-3-(tert-Boc)amino-1,2-epoxy-4-phenylbutane;(2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane;I-Atazanavir Emaphakathi;I-Atazanavir Ukungcola C;i-threo-N-Boc-L-phenylalanine epoxide |
Inombolo ye-CAS | 98760-08-8 |
Inombolo yeCAT | I-RF-PI288 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C15H21NO3 |
Isisindo samangqamuzana | 263.34 |
Isimo Sokuthumela | Ngaphansi Kwezinga Lokushisa Le-Ambient |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | I-Crystalline Powder emhlophe ukuya kokumhlophe |
Ukuhlonza | Umazisi uqinisekiswa yi-HPLC RT |
Ukuncibilika | I-Soluble ku-Methanol |
Ukuzungezisa okuqondile | -10°~ -20° |
Amanzi (KF) | ≤0.50% |
Izinsalela ekushiseni | ≤0.20% |
Izinto Ezihlobene | |
Ukungcola (RRT0.97) | ≤0.30% |
Noma Ikuphi Ukungcola Okukodwa | ≤0.30% |
Ukungcola Okuphelele | ≤1.0% |
Izinsimbi Ezisindayo | ≤20ppm |
Ukuhlanzeka / Indlela Yokuhlaziya | ≥99.0% (HPLC) |
I-Enantiomeric Purity | ≤0.30% |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | I-Intermediate ye-Atazanavir (CAS 198904-31-3) HIV-1 Protease Inhibitor |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, I-Cardboard Drum, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi oholayo kanye nabaphakeli be-(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane (CAS 98760-08-8) enekhwalithi ephezulu, okuphakathi kwe-Atazanavir (CAS 198904-31-3) kanye ne-Atazanavir Sulfate (CAS 229975-97-7).I-Atazanavir iyinoveli ye-azapeptide HIV protease inhibitor (PI).
I-Atazanavir iyisivimbeli se-human immunodeficiency virus type 1 (HIV-1) protease, i-enzyme ebalulekile ekucubunguleni ama-polyprotein e-Gag ne-Gag-Pol abe amaprotheni esakhiwo kanye ne-enzymatic adingekayo ekuphindaphindeni kwegciwane.Ine-pharmacophore motif efanayo kwamanye ama-HIV protease inhibitors ayisithupha athengiswa kabanzi, amaningi awo asekelwe kusifanekiso se-hydroxyethylamine.Ngokukhethekile, ine-aza-peptide motif kodwa igcina izinto eziningi ezifanayo ze-pharmacophore okuhlanganisa izingxenye ze-lipophilic okungenzeka zibophezele ku-S2, S1, S′1, kanye ne-S′2 isikhundla.