(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2 Darunavir Intermediate High Purity
Umkhiqizi Wemikhiqizo Ehlobene ne-Darunavir:
I-Darunavir CAS 206361-99-1
I-Darunavir Ethanolate CAS 635728-49-3
(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2
(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8
(3S)-3-(tert-Butoxycarbonyl)amino-1-Chloro-4-Phenyl-2-Butanone CAS 102123-74-0
| Igama Lekhemikhali | (2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane |
| Omqondofana | (2S,3S)-3-(Boc-Amino)-1,2-Epoxy-4-Phenylbutane;(2S,3S)-3-(tert-Butoxycarbonylamino)-1,2-epoxy-4-phenylbutane;I-Darunavir Intermediate |
| Inombolo ye-CAS | 98737-29-2 |
| Inombolo yeCAT | I-RF-PI286 |
| Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
| I-Molecular Formula | I-C15H21NO3 |
| Isisindo samangqamuzana | 263.33 |
| Ukuncibilika | Ayincibiliki Emanzini.I-Soluble ku-Methanol, i-Chloroform |
| Isimo Sokuthumela | Kuthunyelwe Ngaphansi Kwezinga Lokushisa Le-Ambient |
| Ibhrendi | I-Ruifu Chemical |
| Into | Imininingwane |
| Ukubukeka | I-Crystalline Powder emhlophe ukuya kokumhlophe |
| I-Identification (HPLC) | Ukuhlonza Kuqinisekiswa yi-HPLC |
| I-Melting Point | 123.0~128.0℃ |
| Umswakama (KF) | ≤0.50% |
| Izinsalela ekushiseni | ≤0.20% |
| Ukuhlanzeka / Indlela Yokuhlaziya | ≥99.0% (HPLC) |
| I-Chlorohydrin (HPLC) | ≤0.20% |
| I-Chloromethyl Ketone | ≤0.10% |
| Okunye Ukungcola Okukodwa | ≤0.20% |
| Ukungcola Okuphelele | ≤1.0% |
| Ukungcola KweChiral | ≤0.30% |
| Izinsimbi Ezisindayo | ≤20ppm |
| Izinga Lokuhlola | I-Enterprise Standard |
| Ukusetshenziswa | I-Intermediate of Darunavir (CAS 206361-99-1) HIV-1 Protease Inhibitor |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, I-Cardboard Drum, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi oholayo kanye nabaphakeli be-(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane (CAS: 98737-29-2) enekhwalithi ephezulu , okumaphakathi ngokuvamile ekuhlanganisweni kwe-Darunavir (CAS 206361-99-1) ne-Darunavir Ethanolate (CAS 635728-49-3).
I-Darunavir (CAS 206361-99-1) iwuhlobo olusha lwe-non-peptide anti retroviral protease inhibitors ekwelashweni kwe-AIDS.Yasungulwa okokuqala yigatsha lase-Island le-Johnson pharmaceutical, i-Tibotec.Isezingeni eliphezulu kakhulu le-bioavailability kuma-6 protease inhibitors (saquinavir, ritonavirvir, indinavir, naphthalene nelfinavir, amprenavir kanye ne-ABT378/r).Isebenza ngokuvimbela ukwakheka kwezinhlayiya zegciwane ezintsha nezivuthiwe ebusweni bamaseli aphethwe yigciwane futhi ivimbele i-protease yegciwane.Uma umkhiqizo usetshenziswa isikhathi eside, ngokuvamile unganciphisa i-HIV virus vector egazini, ukhuphule isibalo samaseli e-CD4, unciphise amathuba okutheleleka nge-HIV, uthuthukise izinga lempilo futhi andise impilo.Ilungele abantu abadala abanegciwane lesandulela ngculazi kodwa abangenawo amandla okusebenzisa imishanguzo ekhona.Umuthi kufanele uhlanganiswe nokusetshenziswa kwemithamo ephansi ye-ritonavir noma amanye ama-antiretroviral agents, ukuze kuthuthukiswe ukusebenza kahle kwawo.
