3-Ethynylaniline CAS 54060-30-9 Purity >99.0% (GC) Erlotinib Hydrochloride Intermediate
Umkhiqizi ohamba phambili nomphakeli we-Erlotinib Hydrochloride Intermediates
I-Erlotinib Hydrochloride CAS 183319-69-9
3-Ethynylaniline CAS 54060-30-9
6,7-Bis(2-Methoxyethoxy)-3H-Quinazolin-4-one CAS 179688-29-0
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Igama Lekhemikhali | 3-Ethynylaniline |
Omqondofana | 3-Aminophenylacetylene |
Inombolo ye-CAS | 54060-30-9 |
Inombolo yeCAT | I-RF-PI2241 |
Isimo Sesitoko | Esitokweni, Amandla Okukhiqiza 50MT/Ngenyanga |
I-Molecular Formula | C8H7N |
Isisindo samangqamuzana | 117.15 |
Kuyazwela | Izwela Umoya, Izwela Ukukhanya |
Iphuzu elibilayo | 120℃/20 mmHg |
Ukuncibilika kwamanzi | Ayincibiliki Emanzini |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | Uketshezi Oluphuzi Olukhanyayo ukuya Kunsundu |
Ukuhlanzeka / Indlela Yokuhlaziya | >99.0% (GC) |
Amanzi nguKarl Fischer | <0.50% |
Izinsalela ekushiseni | <0.20% |
Ukungcola Okuphelele | <1.00% |
I-Gravity ethize (20/20℃) | 1.041~1.048 |
I-Refractive Index n20/D | 1.614~1.6195 |
I-Infrared Spectrum | Ivumelana Nesakhiwo |
I-Proton NMR Spectrum | Ivumelana Nesakhiwo |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | Pharmaceutical Intermediate;I-Erlotinib Hydrochloride Intermediate |
Iphakheji: Ibhodlela Elifakwe Fluorinated, 25kg/Drum, noma ngokwezidingo zekhasimende
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama
I-3-Ethynylaniline, eyaziwa nangokuthi i-3-Aminophenylacetylene (CAS: 54060-30-9) isetshenziswa njengendawo ephakathi kwemithi.I-3-Ethynylaniline iyi-intermediate ye-Erlotinib Hydrochloride (CAS: 183319-69-9).I-Erlotinib Hydrochloride iyi-molecule encane i-tyrosine kinase inhibitor esebenza ngokuguqukayo kuma-epidermal growth receptors, i-hydrochloride ye-erlotinib, umuthi oqondiswe kumangqamuzana.I-US Food and Drug Administration (FDA) igunyaze i-erlotinib (i-Tarceva) ehlanganiswe ne-gemcitabine njengendlela yokwelapha yomugqa wokuqala yomdlavuza we-pancreatic othuthuke kakhulu kanye ne-metastatic.Isetshenziswa kakhulu njengokwelashwa komugqa wesibili noma wesithathu kumdlavuza wamaphaphu othuthukisiwe endaweni noma we-metstatic non-small cell lung (NSCLC) futhi njengokwelapha umdlavuza wamaphaphu.Isetshenziswa njenge-tyrosine inhibitor yokwelashwa kwe-NSCLC.I-Erlotinib Hydrochloride, i-quinazoline etholakala kwi-molecule encane inhibitor ye-epidermal growth receptor (EDGFR) tyrosine kinase, yavunywa ngoNovemba, i-2004, yokwelapha umdlavuza wamaphaphu osezingeni eliphezulu noma we-metastatic ongewona omncane.