3-Ethynylaniline CAS 54060-30-9 Purity >99.0% (GC) Erlotinib Hydrochloride Intermediate

Incazelo emfushane:

Igama Lekhemikhali: 3-Ethynylaniline

Amazwi afanayo: 3-Aminophenylacetylene

I-CAS: 54060-30-9

Ubumsulwa: >99.0% (GC)

Ukubukeka: Uketshezi Oluphuzi Olukhanyayo ukuya Kunsundu

I-Intermediate ye-Erlotinib Hydrochloride (CAS: 183319-69-9)

Thintana: UDkt. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Umkhiqizi ohamba phambili nomphakeli we-Erlotinib Hydrochloride Intermediates
I-Erlotinib Hydrochloride CAS 183319-69-9
3-Ethynylaniline CAS 54060-30-9
6,7-Bis(2-Methoxyethoxy)-3H-Quinazolin-4-one CAS 179688-29-0
Please contact: alvin@ruifuchem.com

Chemical Properties:

Igama Lekhemikhali 3-Ethynylaniline
Omqondofana 3-Aminophenylacetylene
Inombolo ye-CAS 54060-30-9
Inombolo yeCAT I-RF-PI2241
Isimo Sesitoko Esitokweni, Amandla Okukhiqiza 50MT/Ngenyanga
I-Molecular Formula C8H7N
Isisindo samangqamuzana 117.15
Kuyazwela Izwela Umoya, Izwela Ukukhanya
Iphuzu elibilayo 120℃/20 mmHg
Ukuncibilika kwamanzi Ayincibiliki Emanzini
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into Imininingwane
Ukubukeka Uketshezi Oluphuzi Olukhanyayo ukuya Kunsundu
Ukuhlanzeka / Indlela Yokuhlaziya >99.0% (GC)
Amanzi nguKarl Fischer <0.50%
Izinsalela ekushiseni <0.20%
Ukungcola Okuphelele <1.00%
I-Gravity ethize (20/20℃) 1.041~1.048
I-Refractive Index n20/D 1.614~1.6195
I-Infrared Spectrum Ivumelana Nesakhiwo
I-Proton NMR Spectrum Ivumelana Nesakhiwo
Izinga Lokuhlola I-Enterprise Standard
Ukusetshenziswa Pharmaceutical Intermediate;I-Erlotinib Hydrochloride Intermediate

Iphakheji nesitoreji:

Iphakheji: Ibhodlela Elifakwe Fluorinated, 25kg/Drum, noma ngokwezidingo zekhasimende

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama

Izinzuzo:

1

I-FAQ:

Isicelo:

I-3-Ethynylaniline, eyaziwa nangokuthi i-3-Aminophenylacetylene (CAS: 54060-30-9) isetshenziswa njengendawo ephakathi kwemithi.I-3-Ethynylaniline iyi-intermediate ye-Erlotinib Hydrochloride (CAS: 183319-69-9).I-Erlotinib Hydrochloride iyi-molecule encane i-tyrosine kinase inhibitor esebenza ngokuguqukayo kuma-epidermal growth receptors, i-hydrochloride ye-erlotinib, umuthi oqondiswe kumangqamuzana.I-US Food and Drug Administration (FDA) igunyaze i-erlotinib (i-Tarceva) ehlanganiswe ne-gemcitabine njengendlela yokwelapha yomugqa wokuqala yomdlavuza we-pancreatic othuthuke kakhulu kanye ne-metastatic.Isetshenziswa kakhulu njengokwelashwa komugqa wesibili noma wesithathu kumdlavuza wamaphaphu othuthukisiwe endaweni noma we-metstatic non-small cell lung (NSCLC) futhi njengokwelapha umdlavuza wamaphaphu.Isetshenziswa njenge-tyrosine inhibitor yokwelashwa kwe-NSCLC.I-Erlotinib Hydrochloride, i-quinazoline etholakala kwi-molecule encane inhibitor ye-epidermal growth receptor (EDGFR) tyrosine kinase, yavunywa ngoNovemba, i-2004, yokwelapha umdlavuza wamaphaphu osezingeni eliphezulu noma we-metastatic ongewona omncane.

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