I-3-HydroxyCephem (3-OH) CAS 54639-48-4 Purity ≥99.0% (HPLC) Cephalosporin Ceftaroline Fosamil Intermediate
Ukunikezwa Komkhiqizi, Ukuhlanzeka Okuphezulu, Ukukhiqizwa Kwezohwebo
Igama Lekhemikhali: 3-HydroxyCephem (3-OH)
I-CAS: 54639-48-4
Igama Lekhemikhali | (6R,7R)-3-Hydroxy-8-oxo-7-[(phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenyl methyl ester |
Omqondofana | 3-HydroxyCephem;3-OH;GHYH |
Inombolo ye-CAS | 54639-48-4 |
Inombolo yeCAT | I-RF-PI560 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C28H24N2O5S |
Isisindo samangqamuzana | 500.57 |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | Impushana Emhlophe noma Engamhlophe |
Ukuhlonza | IR, NMR Positive |
Ukuhlanzeka / Indlela Yokuhlaziya | ≥99.0% (HPLC) |
Umswakama (KF) | ≤0.50% |
Ukungcola Okukodwa | ≤0.50% |
Ukungcola Okuphelele | ≤1.0% |
Izincibilikisi Ezisele | ≤1.0% |
I-Penicillin Potassium Residual | ≤1ppm |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | Okumaphakathi kwe-Cephalosporins-derived inhibitors, i-Ceftaroline Fosamil |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama.
I-3-Hydroxycephem (3-OH) (i-CAS: 54639-48-4), i-chain chain ye-Cephalosporin, isetshenziselwa ukulungisa i-Cephalosporin-derived inhibitors.Ingasetshenziswa futhi ukwenza i-Ceftaroline Fosamil okuyi-antibiotic ye-Cephalosporin.I-Ceftaroline, i-metabolite esebenzayo ye-prodrug i-Ceftaroline Fosamil (i-Zinforo, i-Teflaro), iyisizukulwane esithuthukisiwe, i-Cephalosporin yabazali enomsebenzi obanzi we-antibacterial in vitro ngokumelene namagciwane e-Gram-positive, kuhlanganise ne-methicillin-resistant Staphylococcus aureus (MRSA) kanye nemithi eminingi. I-Streptococcus pneumoniae kanye ne-Gram-negative bacteria, okuhlanganisa i-Haemophilus influenzae ne-Moraxella catarrhalis, kodwa hhayi i-Pseudomonas aeruginosa.