I-3-Methyl-6-Nitroindazole CAS 6494-19-5 Purity >98.0% (HPLC) Isithombe Esifakiwe

I-3-Methyl-6-Nitroindazole CAS 6494-19-5 Ubumsulwa >98.0% (HPLC)

Incazelo emfushane:

Igama Lekhemikhali: 3-Methyl-6-Nitroindazole

CAS: 6494-19-5

Ubumsulwa: >98.0% (HPLC)

Okuphuzi Okukhanyayo ukuya Kokuphuzi Okumnyama kuya Kuphuphu Olunsundu ukuya kuCrystal

Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo

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Incazelo:

Shanghai Ruifu Chemical Co., Ltd. is the leading supplier of 3-Methyl-6-Nitroindazole (CAS: 6494-19-5) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. If you are interested in this product, please send detailed information includes CAS number, product name, quantity to us. Please contact: alvin@ruifuchem.com

Chemical Properties:

Igama Lekhemikhali	I-3-Methyl-6-Nitroindazole
Omqondofana	3-Methyl-6-Nitro-1H-Indozole;6-Nitro-3-Methylindazole
Inombolo ye-CAS	6494-19-5
Inombolo yeCAT	I-RF2682
Isimo Sesitoko	Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula	I-C8H7N3O2
Isisindo samangqamuzana	177.16
I-Melting Point	184.0 ukuze 188.0 ℃
Iphuzu elibilayo	384.9±22.0℃
Ukuminyana	1.437
Ukuncibilika	I-Chloroform (Kancane), i-Methanol (Kancane)
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Into	Imininingwane
Ukubukeka	Okuphuzi Okukhanyayo ukuya Kokuphuzi Okumnyama kuya Kuphuphu Olunsundu ukuya kuCrystal
Ukuhlanzeka / Indlela Yokuhlaziya	>98.0% (HPLC)
I-Melting Point	184.0 ukuze 188.0 ℃
Ukulahlekelwa Ekumisweni	<1.00%
Ukungcola Okuphelele	<2.00%
I-Infrared Spectrum	Ivumelana Nesakhiwo
I-Proton NMR Spectrum	Ivumelana Nesakhiwo
Izinga Lokuhlola	I-Enterprise Standard
Ukusetshenziswa	Pharmaceutical Intermediate;I-Pazopanib Hydrochloride Intermediate

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Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.

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Isicelo:

I-3-Methyl-6-Nitroindazole (i-CAS: 6494-19-5) isetshenziswa njenge-Pharmaceutical Intermediate.Ingasetshenziswa njengendawo ephakathi ye-Pazopanib Hydrochloride (CAS: 635702-64-6).I-Pazopanib Hydrochloride iyacwaningwa futhi yathuthukiswa yi-GlaxoSmithKline, iyinoveli ye-oral vascular generation inhibitor engaphazamisa ukuphila kwesimila esinenkani kanye nokukhula kwemithambo yegazi emisha edingekayo.Iqondise i-vascular endothelial growth factor receptor (VEGFR), isebenza ngokuvimbela i-angiogenesis ye-tumor blood supply.Ilungele i-advanced renal cell carcinoma (ukutholakala kwamangqamuzana omdlavuza kuma-renal tubules), i-soft tissue sarcoma (STS), umdlavuza we-ovarian we-epithelial kanye nokwelashwa komdlavuza wamaphaphu ongewona omncane (NSCLC).I-US Food and Drug Administration (FDA) yagunyaza ngo-Okthoba 19, 2009 ukuthi i-Pazopanib Hydrochloride (igama lokuhweba i-Votrient) ifakwe ohlwini, ukwelashwa kwezidakamizwa kwesithupha okuvunyelwe komdlavuza wezinso kusukela ngo-2005.