I-3-Nitrophthalic Anhydride CAS 641-70-3 Pomalidomide Intermediate Purity >98.0% (HPLC)
I-Ruifu Chemical ingumkhiqizi ohamba phambili we-3-Nitrophthalic Anhydride (CAS: 641-70-3) enekhwalithi ephezulu, ephakathi kwe-Pomalidomide (CAS: 19171-19-8).I-Ruifu Chemical inganikeza ukulethwa komhlaba wonke, intengo encintisanayo, isevisi enhle kakhulu, amanani amancane kanye nenqwaba etholakalayo.Thenga i-3-Nitrophthalic Anhydride,Please contact: alvin@ruifuchem.com
| Igama Lekhemikhali | 3-Nitrophthalic Anhydride |
| Omqondofana | 3-Nitrophthalic Acid Anhydride;4-Nitro-2-Benzofuran-1,3-Dione;4-Nitroisobenzofuran-1,3-Dione;4-Nitro-1,3-isobenzofurandione;I-Pomalidomide Ukungcola A |
| Isimo Sesitoko | Ku-Stock, Commercial Production |
| Inombolo ye-CAS | 641-70-3 |
| I-Molecular Formula | C8H3NO5 |
| Isisindo samangqamuzana | 193.11 g/mol |
| I-Melting Point | 161.0 ukuze 165.0 ℃ |
| Kuyazwela | Kuyazwela Umswakama |
| Ukuncibilika kwamanzi | Ingabola Emanzini |
| I-COA ne-MSDS | Iyatholakala |
| Umsuka | Shanghai, China |
| Ibhrendi | I-Ruifu Chemical |
| Izinto | Amazinga Wokuhlola | Imiphumela |
| Ukubukeka | Okuphuzi Okukhanyayo kuya Kuphuzi Yenaliti Ikristalu noma i-Crystalline Powder | Iyahambisana |
| I-Melting Point | 161.0 ~ 165.0℃ | 163.0~165.0℃ |
| Ukulahlekelwa Ekumisweni | <0.50% | 0.10% |
| Ukuhlanzeka / Indlela Yokuhlaziya | >98.0% (HPLC) | 98.85% |
| I-Infrared Spectrum | Ihambisana Nesakhiwo | Iyahambisana |
| 1H NMR Spectrum | Ihambisana Nesakhiwo | Iyahambisana |
| Isiphetho | Umkhiqizo uhloliwe futhi uthobela imininingwane enikeziwe | |
| Isicelo | I-Intermediate ye-Pomalidomide (CAS: 19171-19-8) | |
Iphakheji:Ibhodlela eliFluorinated, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Ukuzwela emoyeni.Gcina isitsha sivalwe ngokuqinile futhi usigcine endaweni epholile, eyomile futhi enomoya omuhle kude nezinto ezingahambelani.Gcina kude nokukhanya kwelanga;gwema umlilo;gwema umswakama.Gwema ama-oxidizing agents.
Ukuthumela:Zilethe emhlabeni wonke ngendiza, yi-FedEx/DHL Express.Nikeza ukulethwa okusheshayo nokuthembekile.
Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Iminyaka engu-15 Yokuhlangenwe nakho?Sinesipiliyoni seminyaka engaphezu kwe-15 ekwakhiweni nasekuthumeleni kwamanye amazwe uhla olubanzi lwezinga eliphezulu lokuxhumanisa imithi noma amakhemikhali amahle.
Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eKorea, eJapane, e-Australia, njll.
Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.
IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.
Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.
Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.
I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.
Isikhathi sokuthumela? Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe.
Ezokuthutha?By Express (FedEx, DHL), by Air, by Sea.
Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.
Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.
Imigomo Yokukhokha?I-invoyisi ye-Proforma izothunyelwa kuqala ngemva kokuqinisekiswa kwe-oda, kufakwe nemininingwane yethu yasebhange.Inkokhelo nge-T/T (Telex Transfer), PayPal, Western Union, njll.
Izimpawu Zengozi Xi - Iyacasula
Amakhodi Engozi
36/37/38 - Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba.
Incazelo Yokuphepha
S26 - Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha.
I-S36 - Gqoka izingubo ezifanele zokuzivikela.
I-S37/39 - Gqoka amagilavu afanelekile kanye nokuvikela iso/ubuso
I-WGK Germany 3
I-FLUKA BRAND F AMAKHODI 10-21
TSCA Yebo
I-HS Code 2917399090
I-3-Nitrophthalic Anhydride (i-CAS: 641-70-3) isetshenziswa njengendawo ephakathi ye-Pomalidomide (CAS: 19171-19-8).NgoFebhuwari 2013, i-US FDA yagunyaza i-Pomalidomide yokwelashwa kwe-myeloma eminingi (MM) ezigulini ezinokuqhubekela phambili kwesifo ngemuva kokuthola ezinye izindlela zokwelapha umdlavuza.I-Pomalidomide iyi-analog ye-4-amino ye-thalidomide enamandla athuthukisiwe kanye nephrofayili yobuthi ethuthukisiwe.I-pomalidomide ne-thalidomide zenza imiphumela yazo ngokushintsha amasosha omzimba, ukuvimbela i-angiogenesis, ukuphazanyiswa kwemvelo yamathambo/isimila, kanye nokuvinjwa kwephrotheni ye-cereblon.I-Pomalidomide ivimbele ngokunamandla ukwanda kwe-in vitro emigqeni yeseli yabantu ye-MM ehlukahlukene, i-IC50~10 nM, kuyilapho i-thalidomide ikhombisa cishe ukuvimbela okufika ku-100 μM.Kumamodeli wesimila segundane le-MM, imithamo yansuku zonke engu-50 mg/kg ye-pomalidomide iphumele ekuvinjweni okuphawulekayo kokukhula kwesimila ngemva kwezinsuku eziyi-15 zokwelashwa kanye nokuhlehla okuphelele emavikini angu-3-6 uma kuqhathaniswa nezilawuli zokwelashwa kwe-thalidomide ngethamo elifanayo.I-pomalidomide ilungiswa ngokufingqa kwe-3-Nitrophthalic Anhydride ne-3-Aminopiperidine-2,6-Dione elandelwa yi-catalytic hydrogenation yeqembu le-nitro.
