I-3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid CAS 61260-15-9 I-Olaparib Intermediate Factory
Ukuhlanzeka Okuphezulu, Ukukhiqizwa Kwezohwebo
I-Olaparib kanye Nezixhumanisi Ezihlobene:
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I-3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid CAS 61260-15-9
| Igama Lekhemikhali | 3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid |
| Omqondofana | I-Dimethyl 3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonate |
| Inombolo ye-CAS | 61260-15-9 |
| Inombolo yeCAT | I-RF-PI453 |
| Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
| I-Molecular Formula | I-C10H11O5P |
| Isisindo samangqamuzana | 242.17 |
| Ibhrendi | I-Ruifu Chemical |
| Into | Imininingwane |
| Ukubukeka | Impushana Emhlophe noma Ecishe Emhlophe |
| Ubumsulwa | ≥98.0% |
| Umswakama (KF) | ≤0.50% |
| Ukungcola Okuphelele | ≤2.0% |
| Izinga Lokuhlola | I-Enterprise Standard |
| Ukusetshenziswa | Okumaphakathi kwe-Olaparib (CAS: 763113-22-0) PARP-Inhibitor |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama.
I-3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid (CAS: 61260-15-9), i-Olaparib ephakathi (i-CAS: 763113-22-0).I-Olaparib iwuhlobo lwenoveli ye-poly ADP-ribose polymerase (PARP) inhibitors, okuhlanganisa i-PARP1, PARP2, ne-PARP3.I-PARP ilamula indlela yokulungisa i-DNA edlala indima ebalulekile ekulungiseni umonakalo we-DNA kanye ne-apoptosis, ngakho-ke i-olaparib iqondise ngokuqondile endleleni yokulungisa i-DNA yokulungisa i-cell DNA futhi ibe nemiphumela ngokuhlasela ubungozi obubalulekile bamangqamuzana omdlavuza aphethe izinguquko ku-BRCA1 futhi I-BRCA2.Ngenxa yale nqubo, ingasetshenziswa ekwelapheni ukunakekelwa kweziguli ezinomdlavuza we-ovarian ovelayo ophindelelayo ezinofuzo lwe-breast susceptibility gene (BRCA) kanye nokuzwela kumuthi weplatinamu.
